alpha 1d Adrenergic Receptor (ADRA1D) (NM_000678) Human Tagged ORF Clone

CAT#: RC211895

ADRA1D (Myc-DDK-tagged)-Human adrenergic, alpha-1D-, receptor (ADRA1D)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: ADRA1D
• Synonyms: ADRA1; ADRA1A; ADRA1R; ALPHA1; DAR; dJ779E11.2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC211895 representing NM_000678
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGACTTTCCGCGATCTCCTGAGCGTCAGTTTCGAGGGACCCCGCCCGGACAGCAGCGCAGGGGGCTCCA
  GCGCGGGCGGCGGCGGGGGCAGCGCGGGCGGCGCGGCCCCCTCGGAGGGCCCGGCGGTGGGCGGCGTGCC
  GGGGGGCGCGGGCGGCGGCGGCGGCGTGGTGGGCGCAGGCAGCGGCGAGGACAACCGGAGCTCCGCGGGG
  GAGCCGGGGAGCGCGGGCGCGGGCGGCGACGTGAATGGCACGGCGGCCGTCGGGGGACTGGTGGTGAGCG
  CGCAGGGCGTGGGCGTGGGCGTCTTCCTGGCAGCCTTCATCCTTATGGCCGTGGCAGGTAACCTGCTTGT
  CATCCTCTCAGTGGCCTGCAACCGCCACCTGCAGACCGTCACCAACTATTTCATCGTGAACCTGGCCGTG
  GCCGACCTGCTGCTGAGCGCCACCGTACTGCCCTTCTCGGCCACCATGGAGGTTCTGGGCTTCTGGGCCT
  TTGGCCGCGCCTTCTGCGACGTATGGGCCGCCGTGGACGTGCTGTGCTGCACGGCCTCCATCCTCAGCCT
  CTGCACCATCTCCGTGGACCGGTACGTGGGCGTGCGCCACTCACTCAAGTACCCAGCCATCATGACCGAG
  CGCAAGGCGGCCGCCATCCTGGCCCTGCTCTGGGTCGTAGCCCTGGTGGTGTCCGTAGGGCCCCTGCTGG
  GCTGGAAGGAGCCCGTGCCCCCTGACGAGCGCTTCTGCGGTATCACCGAGGAGGCGGGCTACGCTGTCTT
  CTCCTCCGTGTGCTCCTTCTACCTGCCCATGGCGGTCATCGTGGTCATGTACTGCCGCGTGTACGTGGTC
  GCGCGCAGCACCACGCGCAGCCTCGAGGCGGGCGTCAAGCGCGAGCGAGGCAAGGCCTCCGAGGTGGTGC
  TGCGCATCCACTGTCGCGGCGCGGCCACGGGCGCCGACGGGGCGCACGGCATGCGCAGCGCCAAGGGCCA
  CACCTTCCGCAGCTCGCTCTCCGTGCGCCTGCTCAAGTTCTCCCGTGAGAAGAAAGCGGCCAAGACTCTG
  GCCATCGTCGTGGGTGTCTTCGTGCTCTGCTGGTTCCCTTTCTTCTTTGTCCTGCCGCTCGGCTCCTTGT
  TCCCGCAGCTGAAGCCATCGGAGGGCGTCTTCAAGGTCATCTTCTGGCTCGGCTACTTCAACAGCTGCGT
  GAACCCGCTCATCTACCCCTGTTCCAGCCGCGAGTTCAAGCGCGCCTTCCTCCGTCTCCTGCGCTGCCAG
  TGCCGTCGTCGCCGGCGCCGCCGCCCTCTCTGGCGTGTCTACGGCCACCACTGGCGGGCCTCCACCAGCG
  GCCTGCGCCAGGACTGCGCCCCGAGTTCGGGCGACGCGCCCCCCGGAGCGCCGCTGGCCCTCACCGCGCT
  CCCCGACCCCGACCCCGAACCCCCAGGCACGCCCGAGATGCAGGCTCCGGTCGCCAGCCGTCGAAAGCCA
  CCCAGCGCCTTCCGCGAGTGGAGGCTGCTGGGGCCGTTCCGGAGACCCACGACCCAGCTGCGCGCCAAAG
  TCTCCAGCCTGTCGCACAAGATCCGCGCCGGGGGCGCGCAGCGCGCAGAGGCAGCGTGCGCCCAGCGCTC
  AGAGGTGGAGGCTGTGTCCCTAGGCGTCCCACACGAGGTGGCCGAGGGCGCCACCTGCCAGGCCTACGAA
  TTGGCCGACTACAGCAACCTACGGGAGACCGATATT
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC211895 representing NM_000678
  Red=Cloning site Green=Tags(s)
  
  MTFRDLLSVSFEGPRPDSSAGGSSAGGGGGSAGGAAPSEGPAVGGVPGGAGGGGGVVGAGSGEDNRSSAG
  EPGSAGAGGDVNGTAAVGGLVVSAQGVGVGVFLAAFILMAVAGNLLVILSVACNRHLQTVTNYFIVNLAV
  ADLLLSATVLPFSATMEVLGFWAFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTE
  RKAAAILALLWVVALVVSVGPLLGWKEPVPPDERFCGITEEAGYAVFSSVCSFYLPMAVIVVMYCRVYVV
  ARSTTRSLEAGVKRERGKASEVVLRIHCRGAATGADGAHGMRSAKGHTFRSSLSVRLLKFSREKKAAKTL
  AIVVGVFVLCWFPFFFVLPLGSLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQ
  CRRRRRRRPLWRVYGHHWRASTSGLRQDCAPSSGDAPPGAPLALTALPDPDPEPPGTPEMQAPVASRRKP
  PSAFREWRLLGPFRRPTTQLRAKVSSLSHKIRAGGAQRAEAACAQRSEVEAVSLGVPHEVAEGATCQAYE
  LADYSNLRETDI
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_000678
• ORF Size: 1716 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000678.1, NM_000678.2, NM_000678.3, NP_000669.1
• RefSeq Size: 2666
• RefSeq ORF: 1719
• Locus ID: 146
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction
• MW: 60.5 kDa
• Gene Summary: Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1D-adrenergic receptor. Similar to alpha-1B-adrenergic receptor gene, this gene comprises 2 exons and a single intron that interrupts the coding region. [provided by RefSeq, Jul 2008]