KCNQ4 (NM_172163) Human Tagged ORF Clone
CAT#: RC213421L4
- LentiORF®
Lenti ORF clone of Human potassium voltage-gated channel, KQT-like subfamily, member 4 (KCNQ4), transcript variant 2, mGFP tagged
"NM_172163" in other vectors (4)
Product Images
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Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Symbol | KCNQ4 |
Synonyms | DFNA2; DFNA2A; KV7.4 |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC213421).
|
Restriction Sites | SgfI-NotI Cloning Scheme for this gene |
ACCN | NM_172163 |
ORF Size | 1923 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_172163.1, NP_751895.1 |
RefSeq Size | 2173 |
RefSeq ORF | 1926 |
Locus ID | 9132 |
Protein Families | Druggable Genome, Ion Channels: Potassium, Transmembrane |
MW | 71 kDa |
Gene Summary | The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC306729 | KCNQ4 (untagged)-Human potassium voltage-gated channel, KQT-like subfamily, member 4 (KCNQ4), transcript variant 2 |
USD 1,080.00 |
|
RC213421 | KCNQ4 (Myc-DDK-tagged)-Human potassium voltage-gated channel, KQT-like subfamily, member 4 (KCNQ4), transcript variant 2 |
USD 98.00 |
|
RG213421 | KCNQ4 (GFP-tagged) - Human potassium voltage-gated channel, KQT-like subfamily, member 4 (KCNQ4), transcript variant 2 |
USD 460.00 |
|
RC213421L3 | Lenti ORF clone of Human potassium voltage-gated channel, KQT-like subfamily, member 4 (KCNQ4), transcript variant 2, Myc-DDK-tagged |
USD 620.00 |
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