LARP2 (LARP1B) (NM_018078) Human Tagged ORF Clone

CAT#: RC213675

LARP1B (Myc-DDK-tagged)-Human La ribonucleoprotein domain family, member 1B (LARP1B), transcript variant 1

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: LARP1B
• Synonyms: LARP2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC213675 representing NM_018078
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAGAATTGGCCAACACCAAGTGAATTAGTGAACACTGGATTTCAGAGCGTCCTCAGCCAAGGAAATA
  AAAAGCCACAAAATAGAAAAGAAAAAGAAGAGAAGGTTGAAAAGAGAAGTAACAGTGACAGCAAAGAAAA
  CCGGGAAACAAAATTAAATGGTCCTGGTGAAAACGTCAGTGAGGATGAGGCTCAGTCAAGTAATCAACGT
  AAGAGAGCTAATAAGCACAAGTGGGTACCACTCCACTTAGATGTTGTAAGATCAGAGAGTCAAGAAAGAC
  CTGGATCCCGGAACAGCTCAAGATGTCAACCTGAAGCAAATAAACCAACACATAACAATAGGAGAAATGA
  TACACGAAGTTGGAAGCGAGATAGAGAAAAAAGGGATGATCAAGATGACGTTTCCAGTGTGAGAAGTGAG
  GGTGGTAATATCCGAGGTTCCTTTAGAGGTCGAGGAAGAGGCCGAGGACGGGGAAGAGGACGAGGCAGAG
  GAAATCCTCGATTGAACTTTGATTATTCATATGGTTATCAAGAACATGGTGAAAGGACTGATCAACCATT
  TCAAACAGAACTTAATACCAGTATGATGTATTACTATGATGATGGTACAGGTGTACAGGTGTATCCTGTG
  GAAGAAGCATTGCTTAAAGAGTATATTAAGCGTCAAATTGAATATTACTTCAGTGTAGAAAATTTGGAAC
  GAGACTTCTTTCTTCGGGGAAAGATGGATGAACAAGGTTTCTTGCCTATTTCCCTGATTGCTGGTTTTCA
  GCGTGTTCAGGCTCTCACTACAAACCTTAATCTCATCTTAGAGGCACTGAAGGATAGCACAGAAGTAGAA
  ATTGTGGATGAGAAAATGAGAAAAAAGATAGAACCAGAAAAATGGCCAATTCCAGGCCCTCCTCCACGCA
  GTGTGCCACCAACAGACTTCTCTCAACTGATTGATTGTCCAGAGTTTGTACCAGGCCAAGCCTTTTGCTC
  ACATACAGAGTCTGCCCCAAATTCTCCAAGAATTGGAAGCCCATTGAGCCCAAAGAAAAACAGTGAAACA
  AGTATTCTTCAAGCAATGTCTAGAGGTTTGTCTACCAGTTTGCCTGACTTGGACTCAGAACCTTGGATAG
  AAGTTAAAAAAAGACATCAGCCAGCCCCAGTGAAATTGAGGGAATCAGTGTCTGTCCCTGAAGGGTCATT
  AAATCAGCTATGTTCTTCAGAAGAACCAGAACAAGAAGAACTTGATTTTTTGTTTGATGAAGAGATTGAA
  CAAATAGGACGAAAAAACACATTTACTGATTGGTCTGATAATGATTCAGATTATGAAATTGATGACCAAG
  ACTTAAACAAGATTTTGATTGTAACTCAGACACCACCTTATGTGAAAAAACATCCTGGAGGAGATCGAAC
  AGGCACCCACATGTCTCGGGCAAAAATCACATCTGAACTTGCTAAAGTTATCAATGATGGCTTATACTAT
  TATGAACAGGATCTATGGATGGAAGAAGATGAAAACAAACACACAGCCATAAAGCAAGAAGTTGAGAACT
  TTAAGAAGCTAAATCTCATTAGTAAAGAGCAGTTTGAAAACCTAACACCTGAACTTCCTTTTGAGCCAAA
  CCAAGAAGTTCCTGTAGCACCTTCACAGTCCAGGCAAGGAGGTGTTCAAGGAGTGCTTCACATTCCCAAG
  AAAGATTTGACTGATGAATTAGCTCAGAAGTTATTTGATGTTTCAGAAATAACTTCAGCAGCAATGGTTC
  ATTCGTTGCCTACAGCAGTTCCAGAATCTCCTAGAATTCATCCTACAAGAACACCCAAAACACCTCGAAC
  ACCTAGGTTACAAGATCCTAACAAAACACCAAGATTTTATCCTGTTGTTAAAGAACCAAAAGCCATTGAT
  GTAAAGAGTCCAAGAAAGAGAAAAACAAGGCATAGCACAAATCCCCCTCTAGAGTGTCATGTTGGTTGGG
  TAATGGATTCCAGAGACCGTGGGCCAGGAACATCCTCTGTCAGCACTTCAAATGCTTCACCTTCAGAAGG
  CGCACCACTAGCAGGAAGTTATGGATGTACTCCTCATTCATTCCCAAAGTTCCAGCATCCTTCTCATGAA
  CTTTTGAAGGAAAATGGCTTTACCCAACAAGTGTACCACAAGTATCGTCGAAGATGCCTAAGTGAGAGAA
  AACGCTTGGGAATTGGTCAGTCCCAAGAAATGAATACCCTCTTTCGTTTCTGGTCCTTTTTCCTCAGAGA
  TCACTTCAATAAAAAAATGTATGAGGAATTTAGACAACTTGCTTGGGAAGATGCAAAAGAAAATTACAGG
  TATGGGTTAGAATGTCTGTTCAGGTTTTATAGTTATGGACTGGAAAAAAAATTCAGGCGAGAAATTTTTC
  AGGATTTCCAAGAAGAAACCAAAAAAGACTACGAATCTGGTCAGCTGTATGGACTAGAAAAGTTTTGGGC
  TTATTTGAAATATTCTCAATCTAAGACACAGTCTATTGACCCAAAACTTCAGGAATACCTCTGTAGTTTT
  AAGAGGTTAGAAGACTTCCGTGTTGATCCCCCTATTAGTGATGAATTTGGAAGAAAAAGACATTCCTCTA
  CTTCTGGTGAGGAGAGTAATCGTCATAGACTTCCACCTAATTCCTCTACAAAGCCACCAAATGCTGCTAA
  ACCTACATCTACCAGTGAGCTTCAGGTACCAATAAACTCTCCCAGAAGGAATATTTCACCGGAGTCCAGT
  GACAATTCACAT
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC213675 representing NM_018078
  Red=Cloning site Green=Tags(s)
  
  MENWPTPSELVNTGFQSVLSQGNKKPQNRKEKEEKVEKRSNSDSKENRETKLNGPGENVSEDEAQSSNQR
  KRANKHKWVPLHLDVVRSESQERPGSRNSSRCQPEANKPTHNNRRNDTRSWKRDREKRDDQDDVSSVRSE
  GGNIRGSFRGRGRGRGRGRGRGRGNPRLNFDYSYGYQEHGERTDQPFQTELNTSMMYYYDDGTGVQVYPV
  EEALLKEYIKRQIEYYFSVENLERDFFLRGKMDEQGFLPISLIAGFQRVQALTTNLNLILEALKDSTEVE
  IVDEKMRKKIEPEKWPIPGPPPRSVPPTDFSQLIDCPEFVPGQAFCSHTESAPNSPRIGSPLSPKKNSET
  SILQAMSRGLSTSLPDLDSEPWIEVKKRHQPAPVKLRESVSVPEGSLNQLCSSEEPEQEELDFLFDEEIE
  QIGRKNTFTDWSDNDSDYEIDDQDLNKILIVTQTPPYVKKHPGGDRTGTHMSRAKITSELAKVINDGLYY
  YEQDLWMEEDENKHTAIKQEVENFKKLNLISKEQFENLTPELPFEPNQEVPVAPSQSRQGGVQGVLHIPK
  KDLTDELAQKLFDVSEITSAAMVHSLPTAVPESPRIHPTRTPKTPRTPRLQDPNKTPRFYPVVKEPKAID
  VKSPRKRKTRHSTNPPLECHVGWVMDSRDRGPGTSSVSTSNASPSEGAPLAGSYGCTPHSFPKFQHPSHE
  LLKENGFTQQVYHKYRRRCLSERKRLGIGQSQEMNTLFRFWSFFLRDHFNKKMYEEFRQLAWEDAKENYR
  YGLECLFRFYSYGLEKKFRREIFQDFQEETKKDYESGQLYGLEKFWAYLKYSQSKTQSIDPKLQEYLCSF
  KRLEDFRVDPPISDEFGRKRHSSTSGEESNRHRLPPNSSTKPPNAAKPTSTSELQVPINSPRRNISPESS
  DNSH
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_018078
• ORF Size: 2742 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_018078.2, NM_018078.3, NP_060548.2
• RefSeq Size: 3979
• RefSeq ORF: 2745
• Locus ID: 55132
• Domains: LA
• MW: 105.1 kDa
• Gene Summary: This gene encodes a protein containing domains found in the La related protein of Drosophila melanogaster. La motif-containing proteins are thought to be RNA-binding proteins, where the La motif and adjacent amino acids fold into an RNA recognition motif. The La motif is also found in proteins unrelated to the La protein. Alternative splicing has been observed at this locus and multiple variants, encoding distinct isoforms, are described. Additional splice variation has been identified but the full-length nature of these transcripts has not been determined. [provided by RefSeq, Jun 2013]