Desmoglein 4 (DSG4) (NM_177986) Human Tagged ORF Clone

CAT#: RC214121L3

Lenti ORF clone of Human desmoglein 4 (DSG4), transcript variant 2, Myc-DDK-tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: DSG4
• Synonyms: CDGF13; CDHF13; HYPT6; LAH
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC214121).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_177986
• ORF Size: 3120 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_177986.2, NP_817123.1
• RefSeq Size: 3580
• RefSeq ORF: 3123
• Locus ID: 147409
• Protein Families: Transmembrane
• MW: 113.8 kDa
• Gene Summary: This gene encodes a member of the desmoglein subgroup of desmosomal cadherins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a transmembrane component of desmosomes and may play a role in cell-cell adhesion in epithelial cells. Mutations in the gene are associated with localized autosomal recessive hypotrichosis and monilethrix, characterized by impaired hair growth. [provided by RefSeq, May 2016]