Leukotriene B4 Receptor 2 (LTB4R2) (NM_019839) Human Tagged ORF Clone

CAT#: RC214163L4

Lenti ORF clone of Human leukotriene B4 receptor 2 (LTB4R2), transcript variant 1, mGFP tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: LTB4R2
• Synonyms: BLT2; BLTR2; JULF2; KPG_004; LTB4-R 2; LTB4-R2; NOP9
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC214163).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_019839
• ORF Size: 1167 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_019839.1, NP_062813.1
• RefSeq Size: 2799
• RefSeq ORF: 1077
• Locus ID: 56413
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction
• MW: 37.8 kDa
• Gene Summary: Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3. [UniProtKB/Swiss-Prot Function]