Leukotriene B4 Receptor 2 (LTB4R2) (NM_019839) Human Tagged ORF Clone

CAT#: RG214163

LTB4R2 (GFP-tagged) - Human leukotriene B4 receptor 2 (LTB4R2), transcript variant 1

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: LTB4R2
• Synonyms: BLT2; BLTR2; JULF2; KPG_004; LTB4-R 2; LTB4-R2; NOP9
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG214163 representing NM_019839
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCACCTTCTCATCGGGCATCACAGGTGGGGTTTTGCCCCACCCCTGAACGCCCTCTGTGGCGCCTTC
  CACCCACCTGTAGGCCCAGAAGGATGTCGGTCTGCTACCGTCCCCCAGGGAACGAGACACTGCTGAGCTG
  GAAGACTTCGCGGGCCACAGGCACAGCCTTCCTGCTGCTGGCGGCGCTGCTGGGGCTGCCTGGCAACGGC
  TTCGTGGTGTGGAGCTTGGCGGGCTGGCGGCCTGCACGGGGGCGACCGCTGGCGGCCACGCTTGTGCTGC
  ACCTGGCGCTGGCCGACGGCGCGGTGCTGCTGCTCACGCCGCTCTTTGTGGCCTTCCTGACCCGGCAGGC
  CTGGCCGCTGGGCCAGGCGGGCTGCAAGGCGGTGTACTACGTGTGCGCGCTCAGCATGTACGCCAGCGTG
  CTGCTCACCGGCCTGCTCAGCCTGCAGCGCTGCCTCGCAGTCACCCGCCCCTTCCTGGCGCCTCGGCTGC
  GCAGCCCGGCCCTGGCCCGCCGCCTGCTGCTGGCGGTCTGGCTGGCCGCCCTGTTGCTCGCCGTCCCGGC
  CGCCGTCTACCGCCACCTGTGGAGGGACCGCGTATGCCAGCTGTGCCACCCGTCGCCGGTCCACGCCGCC
  GCCCACCTGAGCCTGGAGACTCTGACCGCTTTCGTGCTTCCTTTCGGGCTGATGCTCGGCTGCTACAGCG
  TGACGCTGGCACGGCTGCGGGGCGCCCGCTGGGGCTCCGGGCGGCACGGGGCGCGGGTGGGCCGGCTGGT
  GAGCGCCATCGTGCTTGCCTTCGGCTTGCTCTGGGCCCCCTACCACGCAGTCAACCTTCTGCAGGCGGTC
  GCAGCGCTGGCTCCACCGGAAGGGGCCTTGGCGAAGCTGGGCGGAGCCGGCCAGGCGGCGCGAGCGGGAA
  CTACGGCCTTGGCCTTCTTCAGTTCTAGCGTCAACCCGGTGCTCTACGTCTTCACCGCTGGAGATCTGCT
  GCCCCGGGCAGGTCCCCGTTTCCTCACGCGGCTCTTCGAAGGCTCTGGGGAGGCCCGAGGGGGCGGCCGC
  TCTAGGGAAGGGACCATGGAGCTCCGAACTACCCCTCAGCTGAAAGTGGTGGGGCAGGGCCGCGGCAATG
  GAGACCCGGGGGGTGGGATGGAGAAGGACGGTCCGGAATGGGACCTT
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG214163 representing NM_019839
  Red=Cloning site Green=Tags(s)
  
  MAPSHRASQVGFCPTPERPLWRLPPTCRPRRMSVCYRPPGNETLLSWKTSRATGTAFLLLAALLGLPGNG
  FVVWSLAGWRPARGRPLAATLVLHLALADGAVLLLTPLFVAFLTRQAWPLGQAGCKAVYYVCALSMYASV
  LLTGLLSLQRCLAVTRPFLAPRLRSPALARRLLLAVWLAALLLAVPAAVYRHLWRDRVCQLCHPSPVHAA
  AHLSLETLTAFVLPFGLMLGCYSVTLARLRGARWGSGRHGARVGRLVSAIVLAFGLLWAPYHAVNLLQAV
  AALAPPEGALAKLGGAGQAARAGTTALAFFSSSVNPVLYVFTAGDLLPRAGPRFLTRLFEGSGEARGGGR
  SREGTMELRTTPQLKVVGQGRGNGDPGGGMEKDGPEWDL
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_019839
• ORF Size: 1167 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_019839.1, NP_062813.1
• RefSeq Size: 2799
• RefSeq ORF: 1077
• Locus ID: 56413
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction
• Gene Summary: Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3. [UniProtKB/Swiss-Prot Function]