Activin A Receptor Type IB (ACVR1B) (NM_020328) Human Tagged ORF Clone
CAT#: RC214924L3
- LentiORF®
Lenti-ORF clone of ACVR1B (Myc-DDK-tagged)-Human activin A receptor, type IB (ACVR1B), transcript variant 3
"NM_020328" in other vectors (4)
Product Images
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | ACVR1B |
Synonyms | ACTRIB; ACVRLK4; ALK4; SKR2 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC214924).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_020328 |
ORF Size | 2537 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_020328.2, NP_064733.3 |
RefSeq Size | 1708 bp |
RefSeq ORF | 1641 bp |
Locus ID | 91 |
Cytogenetics | 12q13.13 |
Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
Protein Pathways | Adherens junction, Chronic myeloid leukemia, Colorectal cancer, Cytokine-cytokine receptor interaction, Endocytosis, MAPK signaling pathway, Pancreatic cancer, Pathways in cancer, TGF-beta signaling pathway |
MW | 52.1 kDa |
Gene Summary | 'This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC309438 | ACVR1B (untagged)-Human activin A receptor, type IB (ACVR1B), transcript variant 3 |
USD 820.00 |
|
RC214924 | ACVR1B (Myc-DDK-tagged)-Human activin A receptor, type IB (ACVR1B), transcript variant 3 |
USD 450.00 |
|
RG214924 | ACVR1B (GFP-tagged) - Human activin A receptor, type IB (ACVR1B), transcript variant 3 |
USD 500.00 |
|
RC214924L4 | Lenti-ORF clone of ACVR1B (mGFP-tagged)-Human activin A receptor, type IB (ACVR1B), transcript variant 3 |
USD 650.00 |
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