PPP1R3A (NM_002711) Human Tagged ORF Clone

CAT#: RC215004L4

Lenti ORF clone of Human protein phosphatase 1, regulatory (inhibitor) subunit 3A (PPP1R3A), mGFP tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: PPP1R3A
• Synonyms: GM; PP1G; PPP1R3
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC215004).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_002711
• ORF Size: 3366 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_002711.2, NP_002702.1
• RefSeq Size: 4296
• RefSeq ORF: 3369
• Locus ID: 5506
• Protein Families: Druggable Genome, Phosphatase, Transmembrane
• Protein Pathways: Insulin signaling pathway
• MW: 125.8 kDa
• Gene Summary: The glycogen-associated form of protein phosphatase-1 (PP1) derived from skeletal muscle is a heterodimer composed of a 37-kD catalytic subunit and a 124-kD targeting and regulatory subunit. This gene encodes the regulatory subunit which binds to muscle glycogen with high affinity, thereby enhancing dephosphorylation of glycogen-bound substrates for PP1 such as glycogen synthase and glycogen phosphorylase kinase. [provided by RefSeq, Jul 2008]