GAB2 (NM_012296) Human Tagged ORF Clone
CAT#: RC215374L3
- LentiORF®
Lenti ORF clone of Human GRB2-associated binding protein 2 (GAB2), transcript variant 2, Myc-DDK-tagged
"NM_012296" in other vectors (6)
Product Images
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | GAB2 |
Synonyms | KIAA0571 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC215374).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_012296 |
ORF Size | 2031 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_012296.2 |
RefSeq Size | 6062 |
RefSeq ORF | 1917 |
Locus ID | 9846 |
Protein Families | Druggable Genome |
Protein Pathways | Chronic myeloid leukemia, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis |
MW | 74.5 kDa |
Gene Summary | This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC303953 | GAB2 (untagged)-Human GRB2-associated binding protein 2 (GAB2), transcript variant 2 |
USD 760.00 |
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RC215374 | GAB2 (Myc-DDK-tagged)-Human GRB2-associated binding protein 2 (GAB2), transcript variant 2 |
USD 480.00 |
|
RG215374 | GAB2 (GFP-tagged) - Human GRB2-associated binding protein 2 (GAB2), transcript variant 2 |
USD 530.00 |
|
RC215374L1 | Lenti ORF clone of Human GRB2-associated binding protein 2 (GAB2), transcript variant 2, Myc-DDK-tagged |
USD 680.00 |
|
RC215374L2 | Lenti ORF clone of Human GRB2-associated binding protein 2 (GAB2), transcript variant 2, mGFP tagged |
USD 680.00 |
|
RC215374L4 | Lenti ORF clone of Human GRB2-associated binding protein 2 (GAB2), transcript variant 2, mGFP tagged |
USD 680.00 |
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