MDA5 (IFIH1) (NM_022168) Human Tagged ORF Clone
CAT#: RC215661L4
- LentiORF®
Lenti ORF clone of Human interferon induced with helicase C domain 1 (IFIH1), mGFP tagged
"NM_022168" in other vectors (6)
Product Images
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Symbol | IFIH1 |
Synonyms | AGS7; Hlcd; IDDM19; MDA-5; MDA5; RLR-2; SGMRT1 |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC215661).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_022168 |
ORF Size | 3075 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_022168.2, NP_071451.2 |
RefSeq Size | 3434 |
RefSeq ORF | 3078 |
Locus ID | 64135 |
Domains | DEAD, helicase_C |
Protein Pathways | RIG-I-like receptor signaling pathway |
MW | 116.5 kDa |
Gene Summary | DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19. [provided by RefSeq, Jul 2012] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC125308 | IFIH1 (untagged)-Human interferon induced with helicase C domain 1 (IFIH1) |
USD 1,100.00 |
|
RC215661 | IFIH1 (Myc-DDK-tagged)-Human interferon induced with helicase C domain 1 (IFIH1) |
USD 600.00 |
|
RG215661 | IFIH1 (GFP-tagged) - Human interferon induced with helicase C domain 1 (IFIH1) |
USD 660.00 |
|
RC215661L1 | Lenti ORF clone of Human interferon induced with helicase C domain 1 (IFIH1), Myc-DDK-tagged |
USD 984.00 |
|
RC215661L2 | Lenti ORF clone of Human interferon induced with helicase C domain 1 (IFIH1), mGFP tagged |
USD 800.00 |
|
RC215661L3 | Lenti ORF clone of Human interferon induced with helicase C domain 1 (IFIH1), Myc-DDK-tagged |
USD 800.00 |
{0} Product Review(s)
Be the first one to submit a review