PRAK (MAPKAPK5) (NM_003668) Human Tagged ORF Clone
CAT#: RC216715L4
- LentiORF®
Lenti ORF clone of Human mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), transcript variant 1, mGFP tagged
"NM_003668" in other vectors (7)
Product Images
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Symbol | MAPKAPK5 |
Synonyms | MAPKAP-K5; MK-5; MK5; PRAK |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC216715).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_003668 |
ORF Size | 1413 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_003668.2, NP_003659.2 |
RefSeq Size | 2060 |
RefSeq ORF | 1416 |
Locus ID | 8550 |
Domains | pkinase, TyrKc, S_TKc |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | MAPK signaling pathway |
MW | 53.9 kDa |
Gene Summary | The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2012] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC109943 | MAPKAPK5 (untagged)-Human mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), transcript variant 1 |
USD 310.00 |
|
SC323359 | MAPKAPK5 (untagged)-Kinase deficient mutant (K45M) of Human mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), transcript variant 1 |
USD 760.00 |
|
RC216715 | MAPKAPK5 (Myc-DDK-tagged)-Human mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), transcript variant 1 |
USD 420.00 |
|
RG216715 | MAPKAPK5 (GFP-tagged) - Human mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), transcript variant 1 |
USD 460.00 |
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RC216715L1 | Lenti ORF clone of Human mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), transcript variant 1, Myc-DDK-tagged |
USD 768.00 |
|
RC216715L2 | Lenti ORF clone of Human mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), transcript variant 1, mGFP tagged |
USD 620.00 |
|
RC216715L3 | Lenti ORF clone of Human mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), transcript variant 1, Myc-DDK-tagged |
USD 620.00 |
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