MAP4K5 (NM_006575) Human Tagged ORF Clone

CAT#: RC217191L3

Lenti ORF clone of Human mitogen-activated protein kinase kinase kinase kinase 5 (MAP4K5), transcript variant 1, Myc-DDK-tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: MAP4K5
• Synonyms: GCKR; KHS; KHS1; MAPKKKK5
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC217191).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_006575
• ORF Size: 2538 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_006575.3, NP_006566.2
• RefSeq Size: 4373
• RefSeq ORF: 2541
• Locus ID: 11183
• Domains: pkinase, CNH
• Protein Families: Druggable Genome, Protein Kinase
• MW: 94.9 kDa
• Gene Summary: This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008]