PANK2 (NM_024960) Human Tagged ORF Clone
CAT#: RC217228L3
- LentiORF®
Lenti ORF clone of Human pantothenate kinase 2 (PANK2), transcript variant 3, Myc-DDK-tagged
"NM_024960" in other vectors (4)
Product Images
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Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | PANK2 |
Synonyms | C20orf48; HARP; HSS; NBIA1; PKAN |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC217228).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_024960 |
ORF Size | 837 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_024960.3, NP_079236.3 |
RefSeq Size | 1711 |
RefSeq ORF | 840 |
Locus ID | 80025 |
Domains | Fumble |
Protein Families | Druggable Genome |
Protein Pathways | Metabolic pathways, Pantothenate and CoA biosynthesis |
MW | 30.6 kDa |
Gene Summary | This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC111841 | PANK2 (untagged)-Human pantothenate kinase 2 (PANK2), transcript variant 3 |
USD 660.00 |
|
RC217228 | PANK2 (Myc-DDK-tagged)-Human pantothenate kinase 2 (PANK2), transcript variant 3 |
USD 420.00 |
|
RG217228 | PANK2 (GFP-tagged) - Human pantothenate kinase 2 (PANK2), transcript variant 3 |
USD 460.00 |
|
RC217228L4 | Lenti ORF clone of Human pantothenate kinase 2 (PANK2), transcript variant 3, mGFP tagged |
USD 620.00 |
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