SYTL2 (NM_206928) Human Tagged ORF Clone

CAT#: RC217642

SYTL2 (Myc-DDK-tagged)-Human synaptotagmin-like 2 (SYTL2), transcript variant d

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: SYTL2
• Synonyms: CHR11SYT; EXO4; PPP1R151; SGA72M; SLP2; SLP2A
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC217642 representing NM_206928
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGATGAACCCAATGCAGAACAGGTCTATAATCCCTCTCAGTTTGAGAATTTGAGAAAGTTTTGGGACT
  TAGAAGCTAATTCAAACAGTAAGGATAATGACAAGAATATTACCACCACAAGCCAAAAAAATTCTGCACC
  TTTTAATAGGCAGAAACACAAGGAATTCAGCGACATTAAATTATCAGGTAAAAATACCCATGAAGCAGAG
  GTGCTTCTAAGCCCAAAAAAAGTTATGGCAAGAGAGGAAATGGAGAAATTAAATTCAAAGGGCATACTCC
  AGGTGCTACCAGATGAAATCACATTTCCTTTGAGTCCACTTAGAAAGTATACTTATCAGTTGCCAGGAAA
  TGAGTCATCAAAGGAAAATGTGGAAAAGAATACGGAAGGGATTGTTACTCCAGTGTTTAAGGAAGAAAAG
  GATTACTCAGAACAAGAGATTCAAGAATCCATAATAAAAACCAATGTTTTGTCTAAAGACTGCAAAGACA
  CTTTTAATGACAGCTTGCAGAAACTGCTTTCAGAAACCTCAACACCAGCAATTCAACCCTCTGGTGGAAA
  AGTTCATGGAAAACAAGTGCTTGAACCAAGTGTTTCTGAAAATAGGACATGGCCTCAAAAAACAGATTTT
  GCTGATACTGAGGAAGAAGTCAAAGGACCTGAGAAGATCATTAATGAGCATGTTGACAAAACAGTAGTTC
  ATCCAAAGGTTAAACGGAACTCTTTGACTGCTAGTCTAGACAAACTCCTGAAGGAAGCAACTGGAACTTC
  ACCCTCTCCCTTGCAAGCCAAGTTGGCGCCTGTTATCACTGGAACCAACTCTAAGCTGGAAGAGGGGAGA
  TTTTTTGGAAAAGGGATAGAACAGAGTCACAATACTTCAGCTGATAAGAGAGAAATACTAGCTCCTTTTC
  CAGTGAGAGATGAAACTTTTGGAAATACAGCTCTCCTCAAGAAAGCTGAAAGTGGTGAGTGCCAGCTAAG
  CACACAGAATTTGATTCAGATGGCTGCAGAAGATTCTCATCCATTGGATCCAACTTCCCAGCTTTCCAGA
  AAGGGTTCTTTTGGGGATGTGGCCAGCCCTCCCCAAGATATGCTTTTTCCCCAGGATGCTCATCTTGTTC
  CCCAGGCTAGGGTACACCCTTCTCAAACGGAAATTTCGGAGACTGTAGAGAAAGTCATTCTTCCACCCAG
  ACCTGTATTGAATGATGTAAGTGCTGCATTACAGAAGCTGTGTGGAGAAGTATGGTTAAGTTATCCAGCT
  GGAAGGGAAGTAGGTCCTGGAGAAGTGAACCCAGAATTTCCTGAAGCAGTACAGCCAGTATGTAGCCCCC
  TAAATCCTCCAGGAGTGATATCACCATGGGCTACGATGGACACCATAGTTCCAGACAGGAAGGATTTTTA
  TTCCTCCAATGTAGTTCCTGATAAAACTCATGAAGTTGGATCTTATTTAGCTGCCCAAATGTCTCCATCA
  GACCAGACGCTTAGCTCATTTGCTTCCATTGTTGCTCAATATGGCAAAGGCCTCCCTCAGGAAGTGGAAG
  AAATTGTGAGGGAAACAATTGTTCAACCCAAATCAGAGTTCCTCGAATTCAGTGCTGGCTTAGAAAAACT
  ACTGAAGGAAGAAACTGAAACCTTCCCCTCAAAATATGAAAGTGATACAGGGAATCTTTCTCCATCAAAG
  TTAATAGGTAGTACAGAGGAGCCCAGGCGAGCCACTTCTGAATGCCATCCTGAGGAATTAAAAGAAACAG
  TAGAAAAGGCCGAGGCTCCGTTAATAACTGAGAGTGCTTTTGATGCTGGTTTTGAGAAACTTCTTAAAGA
  AATAACTGAAGCTCCTCCTTATCAGCCCCAGGTGTCAGTGAGAGAAGAAACTCACGAGAAGGAGTCCTCA
  CAGTCAGAGCAGACCAGGTTCTTGGGGACAGTGCCCCATTTTTACAGGGCAGCCTCACAGACCTCTGAAA
  TGAAGGATAAAAGTAATGGTTTGGAATCTCAAGTCAACCAATGTGATAAAATGTTGGGAGGAGACGCACT
  TGTGACTGATTTATTGGTAGATTTTTGTGGTTCCAGAAGTGGAGTTGAGATCCCTAGAACCCCACAACTT
  TATGTGGCTCATGAAATAGGGACCATTAAAACTGTAACCCCCCCAGAGGACAGGGACAGTGAAAGTGGGG
  TTGCAGGGGGACAAGGGACTCTTCAGGAACCTGGCTTTGGAGAGGCTTCTGAAGCAATTAGTGTGTCCAG
  AAATAGGCAACCCATTCCTCTCCTGATGAACAAAGAAAACTCTACAAAAACAAGTAAAGTTGAATTGACT
  CTAGCATCGCCATATATGAAACAAGAGAAAGAGGAAGAAAAAGAAGGTTTCTCTGAGTCTGATTTTTCAG
  ATGGAAACACCAGTTCTAATGCAGAGAGCTGGAGAAATCCTTCCAGTTCAGAAGAAGAACCCAGTCCTGT
  TTTGAAAACTTTGGAAAGGAGTGCCGCTAGGAAAATGCCTTCCAAAAGTCTAGAAGACATTTCATCAGAT
  TCATCAAATCAAGCAAAAGTAGATAATCAGCCAGAAGAATTAGTGCGTAGTGCTGAAGATGTTTCCACAG
  TGCCTACACAACCTGATAATCCATTTTCTCACCCTGACAAACTCAAAAGGATGAGCAAGTCTGTTCCAGC
  ATTTCTCCAAGATGAGAGTGATGACAGAGAAACAGATACAGCATCAGAAAGCAGTTACCAGCTCAGCAGA
  CACAAGAAGAGCCCGAGCTCTTTAACCAATCTTAGCAGCTCCTCTGGCATGACGTCCTTGTCTTCTGTGA
  GTGGCAGTGTGATGAGTGTTTATAGTGGAGACTTTGGCAATCTGGAAGTTAAAGGAAATATTCAGTTTGC
  AATTGAATATGTGGAGTCACTGAAGGAGTTGCATGTTTTTGTGGCCCAGTGTAAGGACTTAGCAGCAGCG
  GATGTAAAAAAACAGCGTTCAGACCCATATGTAAAGGCCTATTTGCTACCAGACAAAGGCAAAATGGGCA
  AGAAGAAAACACTCGTAGTGAAGAAAACCTTGAATCCTGTGTATAACGAAATACTGCGGTATAAAATTGA
  AAAACAAATCTTAAAGACACAGAAATTGAACCTGTCCATTTGGCATCGGGATACATTTAAGCGCAATAGT
  TTCCTAGGGGAGGTGGAACTTGATTTGGAAACATGGGACTGGGATAACAAACAGAATAAACAATTGAGAT
  GGTACCCTCTGAAGCGGAAGACAGCACCAGTTGCCCTTGAAGCAGAAAACAGAGGTGAAATGAAACTAGC
  TCTCCAGTATGTCCCAGAGCCAGTCCCTGGTAAAAAGCTTCCTACAACTGGAGAAGTGCACATCTGGGTG
  AAGGAATGCCTTGATCTACCACTGCTAAGGGGAAGTCATCTAAATTCTTTTGTTAAATGTACCATCCTTC
  CAGATACAAGTAGGAAAAGTCGCCAGAAGACAAGAGCTGTAGGGAAAACCACCAACCCTATCTTCAACCA
  CACTATGGTGTATGATGGGTTCAGGCCTGAAGATCTGATGGAAGCCTGTGTAGAGCTTACTGTCTGGGAC
  CATTACAAATTAACCAACCAATTTTTGGGAGGTCTTCGTATTGGCTTTGGAACAGGTAAAAGTTATGGGA
  CTGAAGTGGACTGGATGGACTCTACTTCAGAGGAAGTTGCTCTCTGGGAGAAGATGGTAAACTCCCCCAA
  TACTTGGATTGAAGCAACACTGCCTCTCAGAATGCTTTTGATTGCCAAGATTTCCAAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC217642 representing NM_206928
  Red=Cloning site Green=Tags(s)
  
  MDEPNAEQVYNPSQFENLRKFWDLEANSNSKDNDKNITTTSQKNSAPFNRQKHKEFSDIKLSGKNTHEAE
  VLLSPKKVMAREEMEKLNSKGILQVLPDEITFPLSPLRKYTYQLPGNESSKENVEKNTEGIVTPVFKEEK
  DYSEQEIQESIIKTNVLSKDCKDTFNDSLQKLLSETSTPAIQPSGGKVHGKQVLEPSVSENRTWPQKTDF
  ADTEEEVKGPEKIINEHVDKTVVHPKVKRNSLTASLDKLLKEATGTSPSPLQAKLAPVITGTNSKLEEGR
  FFGKGIEQSHNTSADKREILAPFPVRDETFGNTALLKKAESGECQLSTQNLIQMAAEDSHPLDPTSQLSR
  KGSFGDVASPPQDMLFPQDAHLVPQARVHPSQTEISETVEKVILPPRPVLNDVSAALQKLCGEVWLSYPA
  GREVGPGEVNPEFPEAVQPVCSPLNPPGVISPWATMDTIVPDRKDFYSSNVVPDKTHEVGSYLAAQMSPS
  DQTLSSFASIVAQYGKGLPQEVEEIVRETIVQPKSEFLEFSAGLEKLLKEETETFPSKYESDTGNLSPSK
  LIGSTEEPRRATSECHPEELKETVEKAEAPLITESAFDAGFEKLLKEITEAPPYQPQVSVREETHEKESS
  QSEQTRFLGTVPHFYRAASQTSEMKDKSNGLESQVNQCDKMLGGDALVTDLLVDFCGSRSGVEIPRTPQL
  YVAHEIGTIKTVTPPEDRDSESGVAGGQGTLQEPGFGEASEAISVSRNRQPIPLLMNKENSTKTSKVELT
  LASPYMKQEKEEEKEGFSESDFSDGNTSSNAESWRNPSSSEEEPSPVLKTLERSAARKMPSKSLEDISSD
  SSNQAKVDNQPEELVRSAEDVSTVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLSR
  HKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAA
  DVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNS
  FLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV
  KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWD
  HYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_206928
• ORF Size: 3768 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_206928.1, NM_206928.2, NP_996811.1
• RefSeq Size: 4759
• RefSeq ORF: 6669
• Locus ID: 54843
• MW: 139.9 kDa
• Gene Summary: The protein encoded by this gene is a synaptotagmin-like protein (SLP) that belongs to a C2 domain-containing protein family. The SLP homology domain (SHD) of this protein has been shown to specifically bind the GTP-bound form of Ras-related protein Rab-27A (RAB27A). This protein plays a role in RAB27A-dependent vesicle trafficking and controls melanosome distribution in the cell periphery. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jun 2009]