RLTPR (CARMIL2) (NM_001013838) Human Tagged ORF Clone

CAT#: RC217662L3

Lenti ORF clone of Human RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing (RLTPR), Myc-DDK-tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: CARMIL2
• Synonyms: CARMIL2b; IMD58; LRRC16C; RLTPR
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC217662).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_001013838
• ORF Size: 4305 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001013838.1, NP_001013860.1
• RefSeq Size: 4512
• RefSeq ORF: 4308
• Locus ID: 146206
• MW: 154.5 kDa
• Gene Summary: This gene encodes a member of the CARMIL (capping protein, Arp2/3, myosin-I linker) family of proteins. The encoded protein interacts with and negatively regulates the heterodimeric capping protein and promotes cell migration. Reduced expression of this gene has been observed in human psoriasis patients. Mutations in this gene cause a human immunodeficiency syndrome characterized by smooth muscle tumors and impaired T-cell function. [provided by RefSeq, May 2017]