RLTPR (CARMIL2) (NM_001013838) Human Untagged Clone

CAT#: SC301911

RLTPR (untagged)-Human RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing (RLTPR)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CARMIL2
• Synonyms: CARMIL2b; IMD58; LRRC16C; RLTPR
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001013838, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCCAGACCCCCGACGGCATCTCCTGTGAGCTCCGAGGCGAGATCACCAGGTTCCTGTGGCCCAAAG
  AGGTGGAGCTGCTGCTGAAAACCTGGCTACCCGGGGAGGGTGCTGTGCAAAACCATGTCCTGGCACTGCT
  ACGATGGAGAGCCTACCTGCTGCACACCACCTGCCTCCCGCTGAGGGTGGACTGCACGTTCAGCTACCTG
  GAGGTCCAGGCCATGGCGCTGCAGGAGACACCCCCTCAGGTCACCTTTGAGCTGGAGTCCCTGCGTGAGC
  TGGTCCTGGAGTTTCCTGGTGTGGCCGCCCTGGAACAGCTGGCCCAGCACGTGGCTGCAGCCATCAAGAA
  GGTCTTCCCTCGCTCGACCCTTGGGAAGCTATTCCGGAGGCCCACACCAGCCTCCATGCTGGCTCGGCTG
  GAGAGAAGCAGCCCCTCGGAGTCCACTGACCCCTGCAGCCCCTGTGGTGGCTTCTTGGAGACATACGAGG
  CTCTGTGTGACTACAATGGCTTCCCTTTCCGAGAGGAGATTCAGTGGGACGTGGACACCATTTACCATCG
  CCAGGGCTGCCGCCATTTCAGCCTGGGAGACTTCAGCCACCTCGGCAGTCGGGACCTGGCCTTGAGTGTG
  GCTGCCCTGTCCTACAACCTGTGGTTCCGGTGCCTCTCCTGTGTGGACATGAAGCTGAGCCTTGAGGTCT
  CAGAACAGATTCTGCACATGATGAGTCAGTCATCACACCTGGAGGAGCTGGTGCTGGAGACCTGCAGCCT
  GAGGGGAGACTTTGTCCGACGACTGGCCCAGGCGCTGGCGGGACACTCAAGCTCTGGGCTGCGGGAGCTC
  AGCCTCGCGGGGAACCTGCTGGATGACCGAGGCATGACTGCACTCAGCAGACACCTCGAGCGTTGTCCAG
  GAGCCCTGAGGAGACTCAGCCTGGCCCAGACAGGGTTGACACCGCGAGGAATGAGGGCTCTGGGCCGGGC
  ACTGGCCACCAATGCCGCCTTCGACTCCACCCTGACCCACCTGGACCTTTCTGGGAATCCTGGGGCGCTG
  GGGGCCTCCGAGGACAGTGGGGGCCTCTATAGCTTCCTGAGCCGTCCTAACGTACTGTCGTTCCTGAATC
  TCGCAGGCACCGACACTGCCCTGGACACTGTGAGGGGGTGCTCCGTGGGGGGATGGATGACCGGCAGGGC
  GGACTGGAGGGCGGGACGGGGAGGGCTCGGTCCCCCCGCGGGTGTAGCCAACAGCCTCCCCCCGCAGCTC
  TTCGCAGCGGTATCCCGAGGCTGCTGCACCAGCCTTACCCACCTCGACGCTTCGAGGAACGTCTTCTCCC
  GCACGAAGTCCCGCGCCGCGCCGGCCGCGCTGCAGCTCTTCCTCAGCCGCGCGCGGACGCTGCGGCACCT
  GGGCCTGGCGGGCTGCAAGCTGCCGCCCGACGCGCTCAGAGCCCTTTTGGATGGCCTCGCGCTCAACACG
  CACCTCCGCGACCTGCACCTGGACCTCAGCGCTTGCGAGCTGCGCTCGGCCGGCGCCCAGGTGATACAAG
  ACTTAGTGTGCGACGCAGGCGCTGTGAGCTCCCTGGATCTGGCGGATAACGGCTTCGGCTCAGACATGGT
  GACTCTGGTGCTGGCCATCGGGAGAAGCCGGTCCCTGAGACATGTGGCGCTTGGAAGGAACTTCAACGTC
  CGGTGCAAGGAGACCCTGGACGACGTCCTGCACCGGATTGTCCAGCTCATGCAGGACGACGATTGTCCTC
  TTCAGTCTCTGTCGGTGGCTGAGTCTCGGCTGAAGCTGGGTGCCAGCGTCCTACTCCGGGCCCTAGCCAC
  CAATCCTAACCTGACCGCGCTGGATATCAGCGGCAACGCCATGGGGGACGCGGGCGCCAAGTTGCTGGCC
  AAGGCGCTGCGGGTCAACTCGAGGCTCCGGTCTGTGGTCTGGGACCGGAACCACACATCTGCTTTGGGTC
  TGCTGGACGTGGCGCAGGCGCTGGAGCAGAACCACAGCCTGAAGGCCATGCCTCTGCCACTGAACGACGT
  GGCCCAGGCGCAGCGCAGCCGCCCGGAACTGACAGCACGTGCAGTCCATCAGATCCAAGCCTGTCTCTTG
  AGGAACAACCGCGCAGACCCTGCCTCTTCTGACCACACGACCCGCCTTCAGCCACTTGGTCTGGTCTCAG
  ACCCCTCAGAGCAGGAAGTGAATGAATTGTGTCAGTCGGTGCAGGAGCATGTGGAGCTGCTGGGCTGTGG
  GGCTGGGCCCCAGGGTGAAGCCGCTGTGCGCCAGGCCGAGGATGCCATCCAAAATGCCAACTTCTCTCTC
  AGCATTCTCCCCATTCTATATGAAGCTGGAAGCTCCCCAAGCCATCACTGGCAGCTTGGGCAGAAGCTGG
  AGGGCCTTCTGAGACAGGTGGGCGAGGTCTGCCGCCAGGACATCCAGGACTTCACTCAGGCCACACTGGA
  CACAGCAAGGAGCCTCTGCCCACAGATGCTGCAGGGATCCAGCTGGAGGGAGCAGCTAGAGGGGGTCCTG
  GCAGGCTCGAGGGGCCTCCCGGAGCTGCTCCCAGAGCAGCTGCTGCAAGATGCCTTCACTAGGCTCAGGG
  ACATGCGGCTATCAATCACGGGGACCTTGGCAGAGAGCATTGTGGCTCAGGCTTTGGCAGGCCTGAGTGC
  AGCCCGGGATCAGCTGGTGGAGAGTCTGGCTCAGCAGGCAACAGTGACAATGCCCCCTGCCCTACCAGCA
  CCGGATGGAGGTGAGCCCAGCCTCCTTGAGCCTGGGGAATTGGAAGGTCTTTTCTTCCCCGAGGAGAAGG
  AAGAGGAGAAGGAGAAGGATGACAGTCCTCCACAGAAATGGCCTGAGCTCAGCCACGGTCTTCACCTGGT
  CCCCTTCATTCACAGTGCTGCTGAGGAAGCGGAGCCGGAGCCCGAGCTGGCGGCTCCGGGAGAAGATGCA
  GAGCCGCAGGCGGGGCCGTCCGCGCGCGGCTCTCCGAGCCCTGCCGCCCCTGGGCCCCCGGCCGGCCCGC
  TGCCCCGCATGGACCTGCCACTGGCGGGGCAGCCCCTGCGCCATCCGACCCGGGCCCGGCCGCGGCCGCG
  CCGCCAGCACCACCACCGCCCGCCGCCGGGGGGCCCCCAGGTACCCCCAGCCTTGCCGCAGGAAGGGAAT
  GGGCTCAGTGCCCGCGTGGACGAGGGCGTGGAGGAATTCTTCTCCAAAAGGCTGATCCAGCAGGATCGCC
  TCTGGGCCCCCGAGGAGGACCCGGCCACTGAGGGGGGCGCCACTCCTGTCCCCCGTACACTGCGAAAGAA
  GCTGGGCACCCTCTTTGCCTTCAAGAAGCCTCGTTCAACGCGGGGTCCACGGACTGATCTAGAGACCAGC
  CCTGGGGCAGCTCCCCGAACCCGAAAAACTACATTTGGCGACCTACTGCGGCCGCCAACCCGTCCCAGCC
  GTGGTGAGGAGCTTGGTGGGGCTGAGGGGGACACCAGCAGCCCTGACCCTGCCGGCAGGAGCCGACCTCG
  CTACACAAGAGATAGCAAGGCCTACTCGATGATACTGCTGCCTGCCGAGGAGGAGGCAACGCTGGGTGCC
  AGACCCGACAAGCGGCGGCCCCTGGAGCGGGGAGAAACAGAACTGGCTCCATCCTTTGAACAGCGGGTAC
  AAGTAATGCTGCAGAGGATAGGCGTCAGCCGAGGCAGCGGGGGTGCCGAAGGCAAGAGGAAGCAAAGCAA
  AGATGGCGAGATCAAGAAAGCTGGCTCAGATGGTGACATTATGGACAGTTCCACGGAGGCCCCTCCCATC
  TCGATCAAGTCCCGCACCCACTCTGTGTCTGCTGACCCTTCCTGCAGACCTGGCCCAGGGAGCCAGGGGC
  CTGAGTCTGCCACCTGGAAGACACTGGGGCAGCAGTTGAATGCGGAGCTCAGGAGCCGTGGTTGGGGCCA
  ACAGGATGGTCCAGGCCCTCCCTCCCCTGGTCAAAGCCCAAGTCCCTGCAGAACCAGCCCCTCCCCAGAC
  AGCCTGGGCCTCCCAGAGGACCCTTGCTTGGGCCCCAGAAATGAAGATGGCCAGCTGAGGCCGAGGCCTC
  TCTCGGCAGGGCGGCGAGCAGTGTCTGTGCATGAGGACCAGCTCCAGGCCCCTGCTGAACGGCCCCTGAG
  GCTGCAGCGCTCCCCCGTCCTCAAACGCAGGCCAAAACTCGAGGCACCTCCATCCCCAAGCCTAGGATCT
  GGCCTTGGAACCGAGCCTCTGCCCCCACAGCCCACAGAGCCCTCCAGCCCTGAGCGGAGCCCACCCTCCC
  CAGCCACAGACCAAAGAGGCGGCGGCCCCAATCCCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001013838
• ORF Size: 4308 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001013838.1, NP_001013860.1
• RefSeq Size: 4512
• RefSeq ORF: 4308
• Locus ID: 146206
• Gene Summary: This gene encodes a member of the CARMIL (capping protein, Arp2/3, myosin-I linker) family of proteins. The encoded protein interacts with and negatively regulates the heterodimeric capping protein and promotes cell migration. Reduced expression of this gene has been observed in human psoriasis patients. Mutations in this gene cause a human immunodeficiency syndrome characterized by smooth muscle tumors and impaired T-cell function. [provided by RefSeq, May 2017]
  Transcript Variant: This variant (1) retains an intron in the 5' coding region and contains an alternate in-frame exon in the 3' coding region compared to variant 2. The encoded isoform (1, also known as CARMIL2a) has the same N- and C-termini but is longer compared to isoform 2.