SSH3BP1 (ABI1) (NM_005470) Human Tagged ORF Clone
CAT#: RC217707L4
- LentiORF®
Lenti ORF clone of Human abl-interactor 1 (ABI1), transcript variant 1, mGFP tagged
"NM_005470" in other vectors (6)
Product Images
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Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Symbol | ABI1 |
Synonyms | ABI-1; ABLBP4; E3B1; NAP1BP; SSH3BP; SSH3BP1 |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC217707).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_005470 |
ORF Size | 1527 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_005470.2 |
RefSeq Size | 3725 |
RefSeq ORF | 1527 |
Locus ID | 10006 |
Domains | SH3 |
MW | 55.1 kDa |
Gene Summary | This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq, Sep 2011] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC116759 | ABI1 (untagged)-Human abl-interactor 1 (ABI1), transcript variant 1 |
USD 850.00 |
|
RC217707 | ABI1 (Myc-DDK-tagged)-Human abl-interactor 1 (ABI1), transcript variant 1 |
USD 470.00 |
|
RG217707 | ABI1 (GFP-tagged) - Human abl-interactor 1 (ABI1), transcript variant 1 |
USD 520.00 |
|
RC217707L1 | Lenti ORF clone of Human abl-interactor 1 (ABI1), transcript variant 1, Myc-DDK-tagged |
USD 828.00 |
|
RC217707L2 | Lenti ORF clone of Human abl-interactor 1 (ABI1), transcript variant 1, mGFP tagged |
USD 670.00 |
|
RC217707L3 | Lenti ORF clone of Human abl-interactor 1 (ABI1), transcript variant 1, Myc-DDK-tagged |
USD 670.00 |
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