SSH3BP1 (ABI1) (NM_005470) Human Untagged Clone

CAT#: SC116759

ABI1 (untagged)-Human abl-interactor 1 (ABI1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ABI1
• Synonyms: ABI-1; ABLBP4; E3B1; NAP1BP; SSH3BP; SSH3BP1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_005470, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCAGAGCTGCAGATGTTACTAGAGGAGGAGATCCCGTCTGGCAAGAGGGCGCTGATCGAGAGTTACC
  AGAACCTGACTCGGGTGGCAGACTACTGTGAAAACAACTACATACAGGCTACAGACAAGAGAAAAGCTTT
  AGAGGAGACCAAAGCCTATACAACCCAATCTCTAGCTAGTGTTGCTTATCAAATAAATGCATTGGCCAAC
  AATGTACTCCAGTTGCTGGATATCCAAGCCTCTCAGCTTCGGAGAATGGAGTCTTCCATCAATCATATCT
  CACAGACTGTGGATATTCATAAGGAGAAAGTGGCACGAAGAGAGATTGGTATTTTGACAACAAATAAGAA
  TACATCAAGAACTCACAAAATAATAGCACCTGCGAATATGGAGCGCCCTGTAAGGTATATTCGGAAACCT
  ATCGATTACACAGTTCTGGATGATGTGGGCCATGGTGTCAAGTGGCTAAAAGCCAAGCATGGAAATAACC
  AGCCTGCAAGAACTGGCACACTGTCGAGAACAAATCCTCCTACTCAGAAACCGCCAAGTCCTCCCATGTC
  AGGCCGGGGAACACTGGGACGGAATACTCCTTATAAAACCCTGGAACCTGTTAAACCCCCAACAGTTCCT
  AATGACTATATGACCAGTCCTGCTAGGCTTGGAAGTCAGCATAGTCCAGGCAGGACAGCATCTTTAAATC
  AGAGACCAAGGACACACAGTGGAAGTAGTGGAGGAAGTGGAAGTCGAGAAAACAGTGGTAGCAGTAGTAT
  TGGCATTCCCATTGCTGTGCCTACACCTTCGCCACCCACTATTGGACCAGAAAACATTTCTGTCCCTCCT
  CCTTCTGGAGCTCCACCAGCACCACCTCTGGCACCACTTCTCCCAGTGAGCACTGTGATAGCAGCCCCGG
  GCTCAGCTCCTGGTTCCCAGTATGGCACAATGACCAGGCAGATATCTCGACACAACTCTACTACTTCTTC
  GACATCTTCTGGTGGATACAGACGAACTCCCTCTGTGACTGCTCAATTTTCTGCTCAGCCTCATGTTAAT
  GGAGGTCCACTTTATTCTCAAAATTCAATTTCTATTGCTCCACCCCCTCCCCCTATGCCTCAGTTGACTC
  CACAGATACCTCTCACAGGCTTCGTGGCCAGGGTGCAGGAAAACATTGCTGATAGTCCAACTCCACCGCC
  ACCACCTCCACCAGATGACATTCCCATGTTTGATGACTCTCCACCTCCCCCACCACCACCACCAGTGGAT
  TATGAAGATGAGGAGGCTGCAGTAGTTCAGTATAATGATCCATATGCAGATGGGGATCCTGCTTGGGCCC
  CCAAGAATTATATTGAGAAAGTTGTTGCAATATATGATTATACAAAAGACAAGGATGATGAGCTGTCATT
  TATGGAGGGTGCAATCATTTATGTTATAAAGAAGAATGATGATGGCTGGTATGAAGGAGTCTGCAATCGA
  GTGACTGGTCTGTTCCCTGGGAACTATGTTGAATCAATCATGCACTATACTGATTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005470 unedited
  TCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGTGAGGTG
  CTCGGAGCCTCGGCGGACCTTGCTGCCTCTGTCTCTTTAACGCGAGAGGAAGCGATGCAG
  AGGGGTGGAAAATGGCAGAGCTGCAGATGTTACTAGAGGAGGAGATCCCGTCTGGCAAGA
  GGGCGCTGATCGAGAGTTACCAGAACCTGACTCGGGTGGCAGACTACTGTGAAAACAACT
  ACATACAGGCTACAGACAAGAGAAAAGCTTTAGAGGAGACCAAAGCCTATACAACCCAAT
  CTCTAGCTAGTGTTGCTTATCAAATAAATGCATTGGCCAACAATGTACTCCAGTTGCTGG
  ATATCCAAGCCTCTCAGCTTCGGAGAATGGAGTCTTCCATCAATCATATCTCACAGACTG
  TGGATATTCATAAGGAGAAAGTGGCACGAAGAGAGATTGGTATTTTGACAACAAATAAGA
  ATACATCAAGAACTCACAAAATAATAGCACCTGCGAATATGGAGCGCCCTGTAAGGTATA
  TTCGGAAACCTATCGATTACACAGTTCTGGATGATGTGGGCCATGGTGTCAAGTGGCTAA
  AAGCCAAGCATGGAAATAACCAGCCTGCAAGAACTGGCACACTGTCGAGAACAAATCCTC
  CTACTCAGAAACCGCCAAGTCCTCCCATGTCAGGCCGGGGAACACTGGNGACGGATACTC
  CTTATAAAACCCTGGAACCTGTTAAACCCCCAACAGTTCCTAATGACTATATGACCAGTC
  CTGCTAGGCTTGGAAGTCAGCATAGTCCAGGCAGGACAGCATCTTTTAATCAGAGACCAA
  GGACACACAGTGGNAAGTAGTGGGAGAAGTTGGAAGTCGAGAAAACAGTGGTAGCAGTAG
  TATTGGCATTCCCATTGCTGTGCCTACACCTTCGNCACCCACTAT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005470 unedited
  CTCTGGACCGGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTCATATAGGA
  GAATGGTTTATTATAAAAGACTGTACATAAAATTTAGACAACAGGTTATATACAAATTAA
  GAGAACAATCCACTTGAAAAATGGAAAGTAAAAGGTAGCTAGCTGATCACTAATGATACT
  TTGTTTGTTTAAAATTAACAAAGGCAAAATGCATATGAAATAGTCACATTGATTTGGTAG
  CAATAATGGTCTTTAATTTTCAAAAATAACTGTTTTGCACTAGTCTTACCATTCACTATG
  CTGTTATAAGTCTGTAGCATCCAGTACATAACTGTAATTTGAATTCCAAACAAATCCTCA
  ATAACACAGAAACCCACACTTGAGTGCTCTACTTTAATATCCTAAGCAATAGAGAATTAT
  ACACAAGACAAGAAGAGAAAACATCCCTCAGCCCTCCCTTCAATTAAGAGGAGACACACA
  AAGTGCATGTGTTGCATTTTGATTATGTCAAAAGACAATCCAAGTCTGTTGGTTAGGTAA
  ATCTCTGTTCACTGATTAATACATGACCCACCTTCTTTCCCAATTATTTTATTTTAAAAT
  TCTAATGTTGCTAGTGCCCAGTAATGGATTAAAGAGTGCCTACTCACAAATCAACTGTAT
  CCACTTTTACAATATGTAAAAAGGTACTTTTTAACTTCCTTTCATTGAACCAGGGTACAA
  CAGGTCACTGTACAACTGAAGGACCGACATGGCAATCCCTTAAGAAATTTACCTACAAAA
  TGAATGCACCCAATTNTGACACATTTTCTTAATTTCAAAAGAATATTCAAAAAGGGAAAT
  CAGTACATGGACTTGTAAATAACCCTGGCCAAATTTGAAATCTGCAAAAACCCGCCCATT
  GTTGTGGGCACAAATAACAATAAGGCCTATAATTTTTTCCCCCTCACAATATTGGGGAAA
  AAAAACACAATTTGCGCCAACAATCTATCTTTTTTTTTTTCAAACCACACACCGAGAAGA
  GCCACACTCTCCCTCCA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_005470
• ORF Size: 1527 bp
• Insert Size: 3220
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_005470.2, NP_005461.2
• RefSeq Size: 3668
• RefSeq ORF: 1527
• Locus ID: 10006
• Domains: SH3
• Gene Summary: This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq, Sep 2011]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.