ARID1A (NM_006015) Human Tagged ORF Clone
CAT#: RC218151L1
- LentiORF®
Lenti ORF clone of Human AT rich interactive domain 1A (SWI-like) (ARID1A), transcript variant 1, Myc-DDK-tagged
"NM_006015" in other vectors (3)
Product Images
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | ARID1A |
Synonyms | B120; BAF250; BAF250a; BM029; C1orf4; CSS2; ELD; hELD; hOSA1; MRD14; OSA1; P270; SMARCF1 |
Vector | pLenti-C-Myc-DDK |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC218151).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_006015 |
ORF Size | 6855 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_006015.3, NP_006006.3 |
RefSeq Size | 8595 |
RefSeq ORF | 6858 |
Locus ID | 8289 |
Protein Families | Druggable Genome |
MW | 241.9 kDa |
Gene Summary | This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC303719 | ARID1A (untagged)-Human AT rich interactive domain 1A (SWI-like) (ARID1A), transcript variant 1 |
USD 4,620.00 |
|
RC218151 | ARID1A (Myc-DDK-tagged)-Human AT rich interactive domain 1A (SWI-like) (ARID1A), transcript variant 1 |
USD 1,999.00 |
|
RG218151 | ARID1A (GFP-tagged) - Human AT rich interactive domain 1A (SWI-like) (ARID1A), transcript variant 1 |
USD 2,200.00 |
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