LRRK1 (NM_024652) Human Tagged ORF Clone

CAT#: RC218814L1

Lenti ORF clone of Human leucine-rich repeat kinase 1 (LRRK1), Myc-DDK-tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: LRRK1
• Synonyms: RIPK6; Roco1
• Vector: pLenti-C-Myc-DDK
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC218814).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_024652
• ORF Size: 6045 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_024652.3, NP_078928.3
• RefSeq Size: 7647
• RefSeq ORF: 6048
• Locus ID: 79705
• Protein Families: Druggable Genome, Protein Kinase
• MW: 225.2 kDa
• Gene Summary: This gene encodes a multi-domain protein that is a leucine-rich repeat kinase and a GDP/GTP binding protein. The encoded protein is thought to play a role in the regulation of bone mass. Mice lacking a similar gene showed severe osteopetrosis, increased bone mineralization and decreased bone resorption. [provided by RefSeq, Jan 2017]