PPM1L (NM_139245) Human Tagged ORF Clone
CAT#: RC218909L3
- LentiORF®
Lenti ORF clone of Human protein phosphatase, Mg2+/Mn2+ dependent, 1L (PPM1L), Myc-DDK-tagged
"NM_139245" in other vectors (7)
Product Images
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Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | PPM1L |
Synonyms | PP2C-epsilon; PP2CE; PPM1-LIKE |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC218909).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_139245 |
ORF Size | 1080 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_139245.2, NP_640338.2 |
RefSeq Size | 3056 |
RefSeq ORF | 1083 |
Locus ID | 151742 |
Domains | PP2C |
Protein Families | Druggable Genome, Phosphatase |
MW | 40.9 kDa |
Gene Summary | The protein encoded by this gene is a magnesium or manganese-requiring phosphatase that is involved in several signaling pathways. The encoded protein downregulates apoptosis signal-regulating kinase 1, a protein that initiates a signaling cascade that leads to apoptosis when cells are subjected to cytotoxic stresses. This protein also is an endoplasmic reticulum transmembrane protein that helps regulate ceramide transport from the endoplasmic reticulum to the Golgi apparatus. Finally, this gene may be involved in adiposity since it is upregulated in adipose tissues. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC125344 | PPM1L (untagged)-Human protein phosphatase, Mg2+/Mn2+ dependent, 1L (PPM1L) |
USD 610.00 |
|
SC317574 | PPM1L (untagged)-Human protein phosphatase, Mg2+/Mn2+ dependent, 1L (PPM1L) |
USD 610.00 |
|
RC218909 | PPM1L (Myc-DDK-tagged)-Human protein phosphatase, Mg2+/Mn2+ dependent, 1L (PPM1L) |
USD 420.00 |
|
RG218909 | PPM1L (GFP-tagged) - Human protein phosphatase, Mg2+/Mn2+ dependent, 1L (PPM1L) |
USD 460.00 |
|
RC218909L1 | Lenti ORF clone of Human protein phosphatase, Mg2+/Mn2+ dependent, 1L (PPM1L), Myc-DDK-tagged |
USD 768.00 |
|
RC218909L2 | Lenti ORF clone of Human protein phosphatase, Mg2+/Mn2+ dependent, 1L (PPM1L), mGFP tagged |
USD 620.00 |
|
RC218909L4 | Lenti ORF clone of Human protein phosphatase, Mg2+/Mn2+ dependent, 1L (PPM1L), mGFP tagged |
USD 620.00 |
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