SMOX (NM_175839) Human Tagged ORF Clone
CAT#: RC218947L2
- LentiORF®
Lenti ORF clone of Human spermine oxidase (SMOX), transcript variant 1, mGFP tagged
"NM_175839" in other vectors (6)
Product Images
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Symbol | SMOX |
Synonyms | C20orf16; PAO; PAO-1; PAO1; PAOH; PAOH1; SMO |
Vector | pLenti-C-mGFP |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC218947).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_175839 |
ORF Size | 1665 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_175839.1, NP_787033.1 |
RefSeq Size | 2203 |
RefSeq ORF | 1668 |
Locus ID | 54498 |
Protein Families | Druggable Genome |
MW | 61.6 kDa |
Gene Summary | Polyamines are ubiquitous polycationic alkylamines which include spermine, spermidine, putrescine, and agmatine. These molecules participate in a broad range of cellular functions which include cell cycle modulation, scavenging reactive oxygen species, and the control of gene expression. These molecules also play important roles in neurotransmission through their regulation of cell-surface receptor activity, involvement in intracellular signalling pathways, and their putative roles as neurotransmitters. This gene encodes an FAD-containing enzyme that catalyzes the oxidation of spermine to spermadine and secondarily produces hydrogen peroxide. Multiple transcript variants encoding different isoenzymes have been identified for this gene, some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates. The characterized isoenzymes have distinctive biochemical characteristics and substrate specificities, suggesting the existence of additional levels of complexity in polyamine catabolism. [provided by RefSeq, Jul 2012] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC313989 | SMOX (untagged)-Human spermine oxidase (SMOX), transcript variant 1 |
USD 930.00 |
|
RC218947 | SMOX (Myc-DDK-tagged)-Human spermine oxidase (SMOX), transcript variant 1 |
USD 480.00 |
|
RG218947 | SMOX (GFP-tagged) - Human spermine oxidase (SMOX), transcript variant 1 |
USD 530.00 |
|
RC218947L1 | Lenti ORF clone of Human spermine oxidase (SMOX), transcript variant 1, Myc-DDK-tagged |
USD 840.00 |
|
RC218947L3 | Lenti ORF clone of Human spermine oxidase (SMOX), transcript variant 1, Myc-DDK-tagged |
USD 680.00 |
|
RC218947L4 | Lenti ORF clone of Human spermine oxidase (SMOX), transcript variant 1, mGFP tagged |
USD 680.00 |
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