EPX (NM_000502) Human Tagged ORF Clone

CAT#: RC218959L3

Lenti-ORF clone of EPX (Myc-DDK-tagged)-Human eosinophil peroxidase (EPX)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: EPX
• Synonyms: EPO; EPP; EPX-PEN; EPXD
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC218959).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_000502
• ORF Size: 2145 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000502.4, NP_000493.1
• RefSeq Size: 2731
• RefSeq ORF: 2148
• Locus ID: 8288
• Domains: An_peroxidase
• Protein Families: Druggable Genome
• Protein Pathways: Asthma
• MW: 81.5 kDa
• Gene Summary: This gene is a member of the peroxidase gene family and is expressed in eosinophils. The encoded preproprotein is proteolytically processed into covalently attached heavy and light chains to form the mature enzyme, which functions as an oxidant. The enzyme is released at sites of parasitic infection or allergen stimulation to mediate lysis of protozoa or parasitic worms. The gene is found in a gene cluster with other peroxidase genes on chromosome 17. Mutations in this gene result in eosinophil peroxidase deficiency. [provided by RefSeq, Feb 2016]