ARHGAP8 (NM_001017526) Human Tagged ORF Clone
CAT#: RC220168L3
- LentiORF®
Lenti ORF clone of Human Rho GTPase activating protein 8 (ARHGAP8), transcript variant 1, Myc-DDK-tagged
"NM_001017526" in other vectors (4)
Product Images
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | ARHGAP8 |
Synonyms | BPGAP1; PP610 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC220168).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_001017526 |
ORF Size | 1392 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001017526.1, NP_001017526.1 |
RefSeq Size | 1725 bp |
RefSeq ORF | 1395 bp |
Locus ID | 23779 |
Cytogenetics | 22q13.31 |
MW | 53.3 kDa |
Gene Summary | This gene encodes a member of the RHOGAP family. GAP (GTPase-activating) family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. GAP proteins alternate between an active (GTP-bound) and inactive (GDP-bound) state based on the GTP:GDP ratio in the cell. This family member is a multidomain protein that functions to promote Erk activation and cell motility. Alternative splicing results in multiple transcript variants. Read-through transcripts from the upstream proline rich 5, renal (PRR5) gene into this gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene. [provided by RefSeq, Nov 2010] |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC302062 | ARHGAP8 (untagged)-Human Rho GTPase activating protein 8 (ARHGAP8), transcript variant 1 |
USD 780.00 |
|
RC220168 | ARHGAP8 (Myc-DDK-tagged)-Human Rho GTPase activating protein 8 (ARHGAP8), transcript variant 1 |
USD 420.00 |
|
RG220168 | ARHGAP8 (GFP-tagged) - Human Rho GTPase activating protein 8 (ARHGAP8), transcript variant 1 |
USD 460.00 |
|
RC220168L4 | Lenti ORF clone of Human Rho GTPase activating protein 8 (ARHGAP8), transcript variant 1, mGFP tagged |
USD 620.00 |
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