PTPRN (NM_002846) Human Tagged ORF Clone
CAT#: RC220230
PTPRN (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, N (PTPRN), transcript variant 1
"NM_002846" in other vectors (4)
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | PTPRN |
Synonyms | IA-2; IA-2/PTP; IA2; ICA512; R-PTP-N |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RC220230 representing NM_002846
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCGGCGCCCGCGGCGGCCTGGGGGTCTCGGGGGATCCGGGGGTCTCCGGCTGCTCCTCTGCCTCCTGC TGCTGAGCAGCCGCCCGGGGGGCTGCAGCGCCGTTAGTGCCCACGGCTGTCTATTTGACCGCAGGCTCTG CTCTCACCTGGAAGTCTGTATTCAGGATGGCTTGTTTGGGCAGTGCCAGGTGGGAGTGGGGCAGGCCCGG CCCCTTTTGCAAGTCACCTCCCCAGTTCTCCAACGCTTACAAGGTGTGCTCCGACAACTCATGTCCCAAG GATTGTCCTGGCACGATGACCTCACCCAGTATGTGATCTCTCAGGAGATGGAGCGCATCCCCAGGCTTCG CCCCCCAGAGCCCCGTCCAAGGGACAGGTCTGGCTTGGCACCCAAGAGACCTGGTCCTGCTGGAGAGCTG CTTTTACAGGACATCCCCACTGGCTCCGCCCCTGCTGCCCAGCATCGGCTTCCACAACCACCAGTGGGCA AAGGTGGAGCTGGGGCCAGCTCCTCTCTGTCCCCTCTGCAGGCTGAGCTGCTCCCGCCTCTCTTGGAGCA CCTGCTGCTGCCCCCACAGCCTCCCCACCCTTCACTGAGTTACGAACCTGCCTTGCTGCAGCCCTACCTG TTCCACCAGTTTGGCTCCCGTGATGGCTCCAGGGTCTCAGAGGGCTCCCCAGGGATGGTCAGTGTCGGCC CCCTGCCCAAGGCTGAAGCCCCTGCCCTCTTCAGCAGAACTGCCTCCAAGGGCATATTTGGGGACCACCC TGGCCACTCCTACGGGGACCTTCCAGGGCCTTCACCTGCCCAGCTTTTTCAAGACTCTGGGCTGCTCTAT CTGGCCCAGGAGTTGCCAGCACCCAGCAGGGCCAGGGTGCCAAGGCTGCCAGAGCAAGGGAGCAGCAGCC GGGCAGAGGACTCCCCAGAGGGCTATGAGAAGGAAGGACTAGGGGATCGTGGAGAGAAGCCTGCTTCCCC AGCTGTGCAGCCAGATGCGGCTCTGCAGAGGCTGGCCGCTGTGCTGGCGGGCTATGGGGTAGAGCTGCGT CAGCTGACCCCTGAGCAGCTCTCCACACTCCTGACCCTGCTGCAGCTACTGCCCAAGGGTGCAGGAAGAA ATCCGGGAGGGGTTGTAAATGTTGGAGCTGATATCAAGAAAACAATGGAGGGGCCGGTGGAGGGCAGAGA CACAGCAGAGCTTCCAGCCCGCACATCCCCCATGCCTGGACACCCCACTGCCAGCCCTACCTCCAGTGAA GTCCAGCAGGTGCCAAGCCCTGTCTCCTCTGAGCCTCCCAAAGCTGCCAGACCCCCTGTGACACCTGTCC TGCTAGAGAAGAAAAGCCCACTGGGCCAGAGCCAGCCCACGGTGGCAGGACAGCCCTCAGCCCGCCCAGC AGCAGAGGAATATGGCTACATCGTCACTGATCAGAAGCCCCTGAGCCTGGCTGCAGGAGTGAAGCTGCTG GAGATCCTGGCTGAGCATGTGCACATGTCCTCAGGCAGCTTCATCAACATCAGTGTGGTGGGACCAGCCC TCACCTTCCGCATCCGGCACAATGAGCAGAACCTGTCTTTGGCTGATGTGACCCAACAAGCAGGGCTGGT GAAGTCTGAACTGGAAGCACAGACAGGGCTCCAAATCTTGCAGACAGGAGTGGGACAGAGGGAGGAGGCA GCTGCAGTCCTTCCCCAAACTGCGCACAGCACCTCACCCATGCGCTCAGTGCTGCTCACTCTGGTGGCCC TGGCAGGTGTGGCTGGGCTGCTGGTGGCTCTGGCTGTGGCTCTGTGTGTGCGGCAGCATGCGCGGCAGCA AGACAAGGAGCGCCTGGCAGCCCTGGGGCCTGAGGGGGCCCATGGTGACACTACCTTTGAGTACCAGGAC CTGTGCCGCCAGCACATGGCCACGAAGTCCTTGTTCAACCGGGCAGAGGGTCCACCGGAGCCTTCACGGG TGAGCAGTGTGTCCTCCCAGTTCAGCGACGCAGCCCAGGCCAGCCCCAGCTCCCACAGCAGCACCCCGTC CTGGTGCGAGGAGCCGGCCCAAGCCAACATGGACATCTCCACGGGACACATGATTCTGGCATACATGGAG GATCACCTGCGGAACCGGGACCGCCTTGCCAAGGAGTGGCAGGCCCTCTGTGCCTACCAAGCAGAGCCAA ACACCTGTGCCACCGCGCAGGGGGAGGGCAACATCAAAAAGAACCGGCATCCTGACTTCCTGCCCTATGA CCATGCCCGCATAAAACTGAAGGTGGAGAGCAGCCCTTCTCGGAGCGATTACATCAACGCCAGCCCCATT ATTGAGCATGACCCTCGGATGCCAGCCTACATAGCCACGCAGGGCCCGCTGTCCCATACCATCGCAGACT TCTGGCAGATGGTGTGGGAGAGCGGCTGCACCGTCATCGTCATGCTGACCCCGCTGGTGGAGGATGGTGT CAAGCAGTGTGACCGCTACTGGCCAGATGAGGGTGCCTCCCTCTACCACGTATATGAGGTGAACCTGGTG TCGGAGCACATCTGGTGCGAGGACTTTCTGGTGCGGAGCTTCTACCTGAAGAACGTGCAGACCCAGGAGA CGCGCACGCTCACGCAGTTCCACTTCCTCAGCTGGCCGGCAGAGGGCACACCGGCCTCCACGCGGCCCCT GCTGGACTTCCGCAGGAAGGTGAACAAGTGCTACCGGGGCCGCTCCTGCCCCATCATCGTGCACTGCAGT GATGGTGCGGGGAGGACCGGCACCTACATCCTCATCGACATGGTCCTGAACCGCATGGCAAAAGGAGTGA AGGAGATTGACATCGCTGCCACCCTGGAGCATGTCCGTGACCAGCGGCCTGGCCTTGTCCGCTCTAAGGA CCAGTTTGAATTTGCCCTGACAGCCGTGGCGGAGGAAGTGAATGCCATCCTCAAGGCCCTGCCCCAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC220230 representing NM_002846
Red=Cloning site Green=Tags(s) MRRPRRPGGLGGSGGLRLLLCLLLLSSRPGGCSAVSAHGCLFDRRLCSHLEVCIQDGLFGQCQVGVGQAR PLLQVTSPVLQRLQGVLRQLMSQGLSWHDDLTQYVISQEMERIPRLRPPEPRPRDRSGLAPKRPGPAGEL LLQDIPTGSAPAAQHRLPQPPVGKGGAGASSSLSPLQAELLPPLLEHLLLPPQPPHPSLSYEPALLQPYL FHQFGSRDGSRVSEGSPGMVSVGPLPKAEAPALFSRTASKGIFGDHPGHSYGDLPGPSPAQLFQDSGLLY LAQELPAPSRARVPRLPEQGSSSRAEDSPEGYEKEGLGDRGEKPASPAVQPDAALQRLAAVLAGYGVELR QLTPEQLSTLLTLLQLLPKGAGRNPGGVVNVGADIKKTMEGPVEGRDTAELPARTSPMPGHPTASPTSSE VQQVPSPVSSEPPKAARPPVTPVLLEKKSPLGQSQPTVAGQPSARPAAEEYGYIVTDQKPLSLAAGVKLL EILAEHVHMSSGSFINISVVGPALTFRIRHNEQNLSLADVTQQAGLVKSELEAQTGLQILQTGVGQREEA AAVLPQTAHSTSPMRSVLLTLVALAGVAGLLVALAVALCVRQHARQQDKERLAALGPEGAHGDTTFEYQD LCRQHMATKSLFNRAEGPPEPSRVSSVSSQFSDAAQASPSSHSSTPSWCEEPAQANMDISTGHMILAYME DHLRNRDRLAKEWQALCAYQAEPNTCATAQGEGNIKKNRHPDFLPYDHARIKLKVESSPSRSDYINASPI IEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYWPDEGASLYHVYEVNLV SEHIWCEDFLVRSFYLKNVQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYRGRSCPIIVHCS DGAGRTGTYILIDMVLNRMAKGVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAEEVNAILKALPQ TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Chromatograms |
CHROMATOGRAMS
![]() Sequencher program is needed, download here. |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_002846 |
ORF Size | 2937 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_002846.1, NM_002846.2, NM_002846.3, NP_002837.1 |
RefSeq Size | 3649 bp |
RefSeq ORF | 2940 bp |
Locus ID | 5798 |
Cytogenetics | 2q35 |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Type I diabetes mellitus |
MW | 105.85 kDa |
Gene Summary | 'The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC303245 | PTPRN (untagged)-Human protein tyrosine phosphatase, receptor type, N (PTPRN), transcript variant 1 |
USD 1,980.00 |
|
RG220230 | PTPRN (GFP-tagged) - Human protein tyrosine phosphatase, receptor type, N (PTPRN), transcript variant 1 |
USD 830.00 |
|
RC220230L3 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, N (PTPRN), transcript variant 1, Myc-DDK-tagged |
USD 950.00 |
|
RC220230L4 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, N (PTPRN), transcript variant 1, mGFP tagged |
USD 950.00 |
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