SPRED1 (NM_152594) Human Tagged ORF Clone

CAT#: RC220714L2

Lenti ORF clone of Human sprouty-related, EVH1 domain containing 1 (SPRED1), mGFP tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: SPRED1
• Synonyms: hSpred1; LGSS; NFLS; PPP1R147; spred-1
• Vector: pLenti-C-mGFP
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC220714).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_152594
• ORF Size: 1332 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_152594.1, NP_689807.1
• RefSeq Size: 3816
• RefSeq ORF: 1335
• Locus ID: 161742
• Domains: WH1
• Protein Pathways: Jak-STAT signaling pathway
• MW: 50.3 kDa
• Gene Summary: The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS). [provided by RefSeq, Jul 2008]