SPRED1 (NM_152594) Human Untagged Clone

CAT#: SC101247

SPRED1 (untagged)-Human sprouty-related, EVH1 domain containing 1 (SPRED1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SPRED1
• Synonyms: hSpred1; LGSS; NFLS; PPP1R147; spred-1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC101247 sequence for NM_152594 edited (data generated by NextGen Sequencing)
  ATGAGCGAGGAGACGGCGACTTCTNNNNNNGATAATAGTTATGCACGAGTGCGAGCTGTG
  GTGATGACCCGAGATGACTCAAGTGGTGGATGGTTACCACTTGGAGGGAGTGGACTAAGC
  AGCGTCACTGTCTTCAAAGTCCCTCATCAGGAAGAGAATGGCTGTGCTGACTTTTTTATC
  CGTGGAGAGCGACTCAGGGACAAAATGGTGGTTTTGGAATGTATGCTTAAAAAAGACCTC
  ATTTATAATAAGGTCACTCCAACATTTCACCACTGGAAGATTGATGACAAAAAGTTTGGT
  CTTACGTTTCAAAGTCCTGCTGATGCTAGGGCTTTTGATAGAGGTATCCGAAGAGCTATA
  GAGGATATTTCTCAAGGATGCCCCGAATCAAAAAATGAAGCTGAAGGGGCAGATGACTTA
  CAAGCAAATGAAGAGGATTCTTCCAGTTCTCTAGTGAAGGATCACCTTTTTCAGCAAGAG
  ACAGTTGTTACCAGTGAGCCTTATAGAAGCTCAAATATAAGACCTTCTCCCTTTGAAGAT
  CTGAATGCCAGAAGAGTCTACATGCAAAGCCAAGCCAATCAGATAACATTTGGTCAGCCA
  GGCTTGGACATTCAGAGCAGAAGTATGGAATACGTACAGCGGCAAATATCCAAGGAATGT
  GGAAGCCTAAAGTCCCAAAATAGGGTCCCTTTGAAATCAATCAGACATGTCAGCTTTCAA
  GATGAGGATGAGATTGTCAGAATAAACCCTCGAGATATCTTAATACGTCGCTATGCAGAC
  TACAGACATCCTGACATGTGGAAAAATGACTTGGAAAGAGATGATGCTGATTCCAGTATT
  CAGTTTTCTAAACCAGACAGTAAAAAATCAGACTATCTGTACTCTTGTGGGGATGAGACT
  AAGTTAAGTTCACCCAAAGACTCTGTGGTATTTAAGACGCAGCCTTCCTCATTAAAAATT
  AAGAAGTCAAAACGAAGAAAAGAGGATGGTGAACGTTCTCGCTGCGTATACTGCCAGGAA
  AGGTTTAATCATGAAGAAAATGTCAGGGGAAAATGTCAGGATGCTCCAGACCCTATTAAA
  AGATGCATATATCAAGTTAGTTGCATGCTCTGTGCAGAGAGCATGTTGTATCATTGTATG
  TCAGACTCAGAGGGAGATTTTTCTGATCCCTGTTCGTGTGACACTAGCGACGACAAGTTC
  TGCTTGCGATGGTTAGCCCTGGTAGCTTTGTCTTTCATTGTACCATGTATGTGCTGCTAC
  GTCCCTTTGAGAATGTGCCATCGCTGTGGTGAGGCATGTGGTTGCTGTGGTGGGAAACAT
  AAAGCTGCTGGATGA
  
  Clone variation with respect to NM_152594.2
  25 g=>n;26 a=>n;27 c=>n;28 a=>n;29 a=>n;30 c=>n;291 g=>a;1044 t=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_152594 unedited
  TTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGCGGTGCTGCTGTTGCTCC
  CCCGCCTGCTGTTGCTCCTCCATCTCCAGATCGGATCACGGTGAGGGAAAGATGAGCGAG
  GAGACGGCGACTTCTGACAACGATAATAGTTATGCACGAGTGCGAGCTGTGGTGATGACC
  CGAGATGACTCAAGTGGTGGATGGTTACCACTTGGAGGGAGTGGACTAAGCAGCGTCACT
  GTCTTCAAAGTCCCTCATCAGGAAGAGAATGGCTGTGCTGACTTTTTTATCCGTGGAGAG
  CGACTCAGGGACAAAATGGTGGTTTTGGAATGTATGCTTAAAAAAGACCTCATTTATAAT
  AAGGTCACTCCAACATTTCACCACTGGAAGATTGATGACAAAAAGTTTGGTCTTACGTTT
  CAAAGTCCTGCTGATGCTAGGGCTTTTGATAGAGGTATCCGAAGAGCTATAGAGGATATT
  TCTCAAGGATGCCCCGAATCAAAAAATGAAGCTGAAGGGGCAGATGACTTACAAGCAAAT
  GAAGAGGATTCTTCCAGTTCTCTAGTGAAGGATCACCTTTTTCAGCAAGAGACAGTTGTT
  ACCAGTGAGCCTTATAGAAGCTCAAATATAAGACCTTCTCCCTTTGAAGATCTGAATGCC
  AGAAGAGTCTACATGCAAAGCCAAGCCAATCAGATAACATTTGGTCAGCCAGGCTTGGAC
  ATTCAGAGCAGAAGTATGGAATACGTACAGCGGCAAATATCCAAGGGATGGTGGAAAGCC
  TAAGTCCCAAATAAGGTCCCTTTGAAATCATNAGACATGTCAGCTTTCAGATGAGGATGA
  GATTGTCAGAATAACCTCGAGATATCTAATACGTCGCTATGCAGACTCAGACATTCTGAC
  ATGTGAAAAAGACT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_152594 unedited
  ATCTGTGNNACCGCGGCCGCTATCTAGNATCGAGTTTTTTTTTTTTTTTTTTCATCACCA
  TAGTTTTTAATGAAGAAACTTGTTTAAAATTGTAAAGGAAAAAATGGGAATGGGACGGCA
  AAATCTTAGCAGCAAAGTGGTTAAACAAATTGAAAATATTAATGCACAAACATTAAAATA
  TTAAAGCATATATGTTGCATATAAAATACAGTACAGAACCAGGAGTTGCACTATACTGAT
  TAGTGCTTAACAGAAGAAATGATTAAATTTGTTCCTCCCAGAAGTATATACACAGTTCAT
  TTCCACAGCATTTTCCTATATAGCCAGCAAGTTATTTTCTTCAGTTATTCACACCTTGAT
  CAAACCTGAATTATAAACTTAGCACTTACAAATATGAAAATTCATTCACAAGGAAAAACA
  GTATTTCCATTTCACCAATAAAAATTTTGAAAGTTAACAGTCTATTCTAGGAAACCAAGT
  TTAGCTGANAACTTCAGGGATGAAGATCATCTGTTGTAGCAGCATTCAAATATATAAACA
  GTAAAAATAAGACTTAAAACTGCTGCCTACAGTGTCATGTTTTGGATTTAGTTCATCCAA
  TTGATTTTTAGTACAAAACTAGAAATACCCTCTTCTTCATAACATCTATAGTTATCAATA
  TATTTTTCTCTTTTCAATGTGAAATAATACTNTCAGATGATCTATATACACAATGTTGTC
  AGTTCAAGCTGTCATATAATATAAATGCTTTTCTAAAAAAAGTATTTACAGACAGTGGTA
  TATACATTGGTCAGTTTGATCTGGGGGCAAAGAAAAAAGCTAACACAGCTTAAGTGTGAT
  ATATAAAAAGAATGATNCNTAAATGACGTTTAANAACCTGCAATAGAAATGAAGCTNCAA
  AAGTATTGTGATTTAAATTTTTATACACTCTGAAACTTCAAGCATTAAAAN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_152594
• ORF Size: 1335 bp
• Insert Size: 4600
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_152594.1, NP_689807.1
• RefSeq Size: 3816
• RefSeq ORF: 1335
• Locus ID: 161742
• Domains: WH1
• Protein Pathways: Jak-STAT signaling pathway
• Gene Summary: The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS). [provided by RefSeq, Jul 2008]