ACTR8 (NM_022899) Human Tagged ORF Clone

CAT#: RC222323L4

Lenti-ORF clone of ACTR8 (mGFP-tagged)-Human ARP8 actin-related protein 8 homolog (yeast) (ACTR8)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: ACTR8
• Synonyms: ARP8; hArp8; INO80N
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC222323).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_022899
• ORF Size: 1872 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_022899.4, NP_075050.3
• RefSeq Size: 3629
• RefSeq ORF: 1875
• Locus ID: 93973
• MW: 70.5 kDa
• Gene Summary: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA reoplication and probably DNA repair. Required for the recruitment of INO80 (and probably the INO80 complex) to sites of DNA damage. Strongly prefer nucleosomes and H3-H4 tetramers over H2A-H2B dimers, suggesting it may act as a nucleosome recognition module within the complex. [UniProtKB/Swiss-Prot Function]