ACTR8 (NM_022899) Human Tagged ORF Clone

CAT#: RG222323

ACTR8 (GFP-tagged) - Human ARP8 actin-related protein 8 homolog (yeast) (ACTR8)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: ACTR8
• Synonyms: ARP8; hArp8; INO80N
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG222323 representing NM_022899
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGACCCAGGCTGAGAAGGGTGATACGGAGAACGGAAAGGAGAAGGGCGGCGAGAAGGAGAAGGAGCAGC
  GCGGCGTGAAGCGGCCCATCGTGCCCGCGCTGGTGCCGGAGTCGCTGCAAGAGCAAATCCAGAGCAACTT
  CATCATTGTCATACATCCAGGTTCAACAACTTTAAGGATTGGTCGAGCCACAGACACTCTTCCTGCCAGC
  ATTCCTCACGTCATTGCCCGAAGACACAAACAACAAGGGCAGCCCCTATACAAGGACAGTTGGCTCCTAA
  GGGAGGGACTAAATAAACCAGAAAGTAATGAACAAAGACAAAATGGCCTTAAAATGGTGGATCAAGCAAT
  ATGGTCTAAAAAGATGTCCAATGGTACAAGACGCATTCCTGTGTCCCCTGAACAGGCACGCTCCTACAAT
  AAGCAGATGCGACCTGCAATTTTAGATCACTGTTCGGGAAATAAGTGGACAAACACATCTCATCACCCTG
  AGTATTTAGTAGGAGAAGAGGCCTTGTATGTTAATCCACTGGACTGTTACAATATTCACTGGCCTATCAG
  AAGAGGTCAGTTAAATATTCACCCAGGCCCTGGGGGCTCTCTTACAGCTGTTCTGGCAGATATTGAAGTA
  ATATGGTCTCATGCGATACAAAAATACTTGGAAATCCCACTGAAAGATTTAAAGTATTATAGATGTATCT
  TGTTAATTCCTGATATCTATAATAAGCAGCATGTGAAAGAACTAGTGAATATGATACTAATGAAGATGGG
  TTTTTCAGGGATTGTGGTCCATCAGGAGTCTGTGTGTGCCACCTATGGAAGTGGCTTAAGCAGCACGTGT
  ATTGTAGACGTTGGGGACCAGAAGACAAGTGTATGCTGTGTGGAGGATGGGGTGTCTCATCGGAATACTC
  GGCTTTGTCTGGCATACGGAGGATCTGATGTGTCAAGATGTTTTTACTGGCTAATGCAGCGAGCTGGGTT
  CCCTTACAGAGAATGCCAGTTAACAAATAAAATGGATTGTCTTCTTCTGCAACACCTTAAAGAAACTTTT
  TGTCATTTAGATCAGGACATCTCTGGGCTTCAGGACCATGAGTTTCAGATTCGACATCCTGATTCTCCTG
  CCCTGCTTTACCAGTTTCGATTAGGAGATGAAAAACTGCAGGCTCCAATGGCTTTGTTTTACCCCGCAAC
  TTTTGGAATCGTTGGACAGAAAATGACGACTTTGCAGCACAGATCTCAGGGCGATCCTGAGGATCCTCAC
  GATGAACATTACCTGCTGGCCACACAGAGCAAACAAGAACAGTCTGCAAAAGCTACTGCTGACCGAAAGT
  CTGCATCCAAACCTATTGGATTTGAAGGGGATCTTCGTGGCCAGTCCTCTGATCTTCCAGAAAGACTCCA
  TTCCCAGGAGGTAGATTTGGGGTCTGCACAGGGAGATGGCCTGATGGCCGGCAACGATTCCGAGGAGGCC
  CTCACTGCACTGATGTCCAGGAAGACTGCCATCTCGCTGTTTGAAGGAAAAGCCCTGGGCCTGGATAAAG
  CCATCCTCCATAGCATAGACTGCTGTTCATCTGACGACACCAAAAAGAAGATGTACAGCTCCATCCTAGT
  GGTGGGAGGTGGTTTGATGTTTCATAAAGCTCAAGAATTTCTGCAGCACAGAATTCTCAACAAAATGCCA
  CCATCCTTCAGGCGAATTATTGAAAATGTGGATGTGATCACAAGGCCTAAGGACATGGACCCCCGGCTGA
  TTGCATGGAAAGGAGGGGCAGTGTTGGCTTGTTTGGATACAACACAGGAACTGTGGATTTATCAGCGAGA
  GTGGCAGCGCTTTGGTGTCCGCATGTTACGAGAGCGGGCTGCGTTTGTGTGG
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG222323 representing NM_022899
  Red=Cloning site Green=Tags(s)
  
  MTQAEKGDTENGKEKGGEKEKEQRGVKRPIVPALVPESLQEQIQSNFIIVIHPGSTTLRIGRATDTLPAS
  IPHVIARRHKQQGQPLYKDSWLLREGLNKPESNEQRQNGLKMVDQAIWSKKMSNGTRRIPVSPEQARSYN
  KQMRPAILDHCSGNKWTNTSHHPEYLVGEEALYVNPLDCYNIHWPIRRGQLNIHPGPGGSLTAVLADIEV
  IWSHAIQKYLEIPLKDLKYYRCILLIPDIYNKQHVKELVNMILMKMGFSGIVVHQESVCATYGSGLSSTC
  IVDVGDQKTSVCCVEDGVSHRNTRLCLAYGGSDVSRCFYWLMQRAGFPYRECQLTNKMDCLLLQHLKETF
  CHLDQDISGLQDHEFQIRHPDSPALLYQFRLGDEKLQAPMALFYPATFGIVGQKMTTLQHRSQGDPEDPH
  DEHYLLATQSKQEQSAKATADRKSASKPIGFEGDLRGQSSDLPERLHSQEVDLGSAQGDGLMAGNDSEEA
  LTALMSRKTAISLFEGKALGLDKAILHSIDCCSSDDTKKKMYSSILVVGGGLMFHKAQEFLQHRILNKMP
  PSFRRIIENVDVITRPKDMDPRLIAWKGGAVLACLDTTQELWIYQREWQRFGVRMLRERAAFVW
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_022899
• ORF Size: 1872 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_022899.4, NP_075050.3
• RefSeq Size: 3629
• RefSeq ORF: 1875
• Locus ID: 93973
• Gene Summary: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA reoplication and probably DNA repair. Required for the recruitment of INO80 (and probably the INO80 complex) to sites of DNA damage. Strongly prefer nucleosomes and H3-H4 tetramers over H2A-H2B dimers, suggesting it may act as a nucleosome recognition module within the complex. [UniProtKB/Swiss-Prot Function]