DAB2IP (NM_138709) Human Tagged ORF Clone

CAT#: RC222536

DAB2IP (Myc-DDK-tagged)-Human DAB2 interacting protein (DAB2IP), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: DAB2IP
• Synonyms: AF9Q34; AIP-1; AIP1; DIP1/2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC222536 representing NM_138709
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCCGAGGCTGAAGGAGTCTCGCTCCCACGAGTCCCTGCTCAGCCCCAGCAGTGCGGTGGAGGCGCTGG
  ACCTCAGCATGGAGGAAGAGGTGGTCATCAAGCCCGTGCACAGCAGCATCCTTGGCCAGGACTACTGCTT
  CGAGGTGACGACGTCATCAGGAAGCAAGTGCTTTTCCTGCCGGTCTGCAGCTGAGCGGGATAAGTGGATG
  GAGAACCTCCGGCGAGCGGTGCATCCCAACAAGGACAACAGCCGGCGTGTGGAGCACATCCTGAAGCTGT
  GGGTGATCGAGGCCAAGGACCTGCCAGCCAAGAAGAAGTACCTGTGCGAGCTGTGCCTGGACGATGTGCT
  CTATGCCCGCACCACGGGCAAGCTCAAGACGGACAATGTTTTCTGGGGCGAGCACTTCGAGTTCCACAAC
  TTGCCGCCTCTGCGCACGGTCACTGTCCACCTGTACCGGGAGACCGACAAGAAGAAGAAGAAGGAGCGCA
  ACAGTTACCTGGGCCTGGTGAGCCTACCTGCTGCCTCGGTGGCCGGGCGGCAGTTCGTGGAGAAGTGGTA
  CCCGGTGGTGACGCCCAACCCCAAGGGCGGCAAGGGCCCTGGACCCATGATCCGCATCAAGGCGCGCTAC
  CAAACCATCACCATCCTGCCCATGGAGATGTACAAAGAGTTCGCTGAGCACATCACCAACCACTACCTGG
  GGCTGTGTGCAGCCCTCGAGCCCATCCTCAGTGCCAAGACCAAGGAGGAGATGGCATCTGCCCTGGTGCA
  CATCCTGCAGAGCACGGGCAAGGTGAAGGACTTCCTGACAGACCTGATGATGTCAGAGGTGGACCGCTGC
  GGGGACAACGAGCACCTCATCTTCCGGGAGAACACACTGGCCACCAAGGCCATTGAGGAGTACCTCAAGC
  TAGTGGGCCAGAAGTACCTGCAGGACGCCCTAGGTGAGTTCATCAAAGCGCTGTATGAGTCAGATGAGAA
  CTGCGAAGTGGATCCCAGCAAGTGCTCGGCCGCTGACCTCCCAGAGCACCAGGGCAACCTCAAGATGTGC
  TGCGAGCTGGCCTTCTGCAAGATCATCAACTCCTACTGTGTCTTCCCACGGGAGTTGAAAGAGGTGTTTG
  CCTCGTGGAGGCAGGAGTGCAGCAGTCGCGGCCGCCCGGACATCAGTGAGCGGCTCATCAGCGCCTCCCT
  CTTCCTGCGCTTCCTCTGCCCAGCCATCATGTCGCCCTCACTCTTCAACCTGCTGCAGGAGTACCCTGAT
  GACCGCACTGCCCGCACCCTCACCCTCATCGCCAAGGTCACCCAGAACCTGGCCAACTTTGCCAAATTTG
  GCAGCAAGGAGGAATACATGTCCTTCATGAACCAGTTCCTAGAGCATGAGTGGACCAACATGCAGCGCTT
  CCTGCTGGAGATCTCCAACCCCGAGACCCTCTCCAATACAGCCGGCTTCGAGGGCTACATCGACCTGGGC
  CGCGAGCTCTCCAGCCTGCACTCACTGCTCTGGGAGGCCGTCAGCCAGCTGGAGCAGAGCATAGTATCCA
  AACTGGGACCCCTGCCTCGGATCCTGAGGGACGTCCACACAGCACTGAGCACCCCAGGTAGCGGGCAGCT
  CCCAGGGACCAATGACCTGGCCTCCACACCGGGCTCTGGCAGCAGCAGCATCTCAGCTGGGCTGCAGAAG
  ATGGTGATTGAGAACGATCTTTCCGGTCTGATAGATTTCACCCGGTTACCGTCTCCAACCCCCGAAAACA
  AGGACTTGTTTTTTGTCACAAGGTCCTCCGGGGTCCAGCCCTCACCTGCCCGCAGCTCGAGTTACTCGGA
  AGCCAACGAGCCTGATCTTCAGATGGCCAACGGTGGCAAGAGCCTCTCCATGGTGGACCTCCAGGACGCC
  CGCACGCTGGATGGGGAGGCAGGCTCCCCGGCGGGCCCCGACGTCCTCCCCACAGATGGGCAGGCCGCTG
  CAGCTCAGCTGGTGGCCGGGTGGCCGGCCCGGGCAACCCCAGTGAACCTGGCAGGGCTGGCCACGGTGCG
  GCGGGCAGGCCAGACACCAACCACACCAGGCACCTCCGAGGGCGCGCCAGGCCGGCCCCAGCTGTTGGCA
  CCGCTCTCCTTCCAGAACCCTGTGTACCAGATGGCGGCTGGCCTGCCGCTGTCACCCCGTGGCCTTGGCG
  ACTCAGGCTCTGAGGGCCACAGCTCCCTGAGCTCACACAGCAACAGCGAGGAGTTGGCGGCTGCTGCCAA
  GCTGGGAAGTTTCAGCACTGCCGCGGAGGAGCTGGCTCGGCGGCCCGGTGAGCTGGCACGGCGACAGATG
  TCACTGACTGAAAAAGGCGGGCAGCCCACGGTGCCACGGCAGAACAGTGCTGGCCCCCAGAGGAGGATCG
  ACCAGCCTCCGCCCCCACCCCCGCCGCCACCTCCTGCCCCCCGCGGCCGGACGCCCCCCAACCTGCTGAG
  CACCCTGCAGTACCCAAGACCCTCAAGCGGAACCCTGGCGTCGGCCTCACCTGATTGGGTGGGCCCCAGT
  ACCCGCCTGAGGCAGCAGTCCTCTTCCTCCAAGGGGGACAGCCCAGAACTGAAGCCACGGGCAGTGCACA
  AGCAGGGCCCTTCACCTGTGAGCCCCAATGCCCTGGACCGCACAGCCGCTTGGCTCTTGACCATGAACGC
  GCAGTTGTTAGAAGACGAGGGCCTGGGCCCAGACCCCCCCCACAGGGATAGGCTAAGGAGTAAGGACGAG
  CTCAGCCAAGCAGAAAAGGACCTGGCGGTGCTGCAGGACAAGCTGCGAATCTCCACCAAGAAGCTGGAGG
  AGTATGAGACCCTGTTCAAGTGCCAGGAGGAGACGACGCAGAAGCTGGTGCTGGAGTACCAGGCACGGCT
  GGAGGAGGGCGAGGAGCGGCTGCGGCGGCAGCAGGAGGACAAGGACATCCAGATGAAGGGCATCATCAGC
  AGGTTGATGTCCGTGGAGGAAGAACTGAAGAAGGACCACGCAGAGATGCAAGCGGCTGTGGACTCCAAAC
  AGAAGATCATTGATGCCCAGGAGAAGCGCATTGCCTCGTTGGATGCCGCCAATGCCCGCCTCATGAGTGC
  CCTGACCCAGCTGAAAGAGAGGTACAGCATGCAAGCCCGTAACGGCATCTCCCCCACCAACCCCACCAAA
  TTGCAGATTACTGAGAACGGCGAGTTCAGAAACAGCAGCAATTGT
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC222536 representing NM_138709
  Red=Cloning site Green=Tags(s)
  
  MPRLKESRSHESLLSPSSAVEALDLSMEEEVVIKPVHSSILGQDYCFEVTTSSGSKCFSCRSAAERDKWM
  ENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTGKLKTDNVFWGEHFEFHN
  LPPLRTVTVHLYRETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWYPVVTPNPKGGKGPGPMIRIKARY
  QTITILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRC
  GDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCSAADLPEHQGNLKMC
  CELAFCKIINSYCVFPRELKEVFASWRQECSSRGRPDISERLISASLFLRFLCPAIMSPSLFNLLQEYPD
  DRTARTLTLIAKVTQNLANFAKFGSKEEYMSFMNQFLEHEWTNMQRFLLEISNPETLSNTAGFEGYIDLG
  RELSSLHSLLWEAVSQLEQSIVSKLGPLPRILRDVHTALSTPGSGQLPGTNDLASTPGSGSSSISAGLQK
  MVIENDLSGLIDFTRLPSPTPENKDLFFVTRSSGVQPSPARSSSYSEANEPDLQMANGGKSLSMVDLQDA
  RTLDGEAGSPAGPDVLPTDGQAAAAQLVAGWPARATPVNLAGLATVRRAGQTPTTPGTSEGAPGRPQLLA
  PLSFQNPVYQMAAGLPLSPRGLGDSGSEGHSSLSSHSNSEELAAAAKLGSFSTAAEELARRPGELARRQM
  SLTEKGGQPTVPRQNSAGPQRRIDQPPPPPPPPPPAPRGRTPPNLLSTLQYPRPSSGTLASASPDWVGPS
  TRLRQQSSSSKGDSPELKPRAVHKQGPSPVSPNALDRTAAWLLTMNAQLLEDEGLGPDPPHRDRLRSKDE
  LSQAEKDLAVLQDKLRISTKKLEEYETLFKCQEETTQKLVLEYQARLEEGEERLRRQQEDKDIQMKGIIS
  RLMSVEEELKKDHAEMQAAVDSKQKIIDAQEKRIASLDAANARLMSALTQLKERYSMQARNGISPTNPTK
  LQITENGEFRNSSNC
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_138709
• ORF Size: 3195 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_138709.1, NM_138709.2, NP_619723.1
• RefSeq Size: 3500
• RefSeq ORF: 3198
• Locus ID: 153090
• MW: 117.5 kDa
• Gene Summary: DAB2IP is a Ras (MIM 190020) GTPase-activating protein (GAP) that acts as a tumor suppressor. The DAB2IP gene is inactivated by methylation in prostate and breast cancers (Yano et al., 2005 [PubMed 15386433]). [supplied by OMIM, May 2010]