PTPN20A (NM_001042387) Human Tagged ORF Clone

CAT#: RC223995

PTPN20A (Myc-DDK-tagged)-Human protein tyrosine phosphatase, non-receptor type 20A (PTPN20A), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: PTPN20A
• Synonyms: bA142I17.1; CT126; hPTPN20; PTPN20B
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC223995 ORF sequence
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTCTTCACCTAGGGACTTTAGAGCAGAGCCTGTAAACGATTATGAGGGAAATGACTCTGAAGCAGAAG
  ACTTGAATTTCAGGGAGACTTTGCCTTCATCAAGTCAGGAAAACACACCTAGATCAAAGGTTTTTGAAAA
  TAAAGTTAATTCAGAGAAGGTAAAACTTTCTCTTCGGAATTTCCCACATAATGATTATGAGGATGTTTTT
  GAAGAGCCTTCAGAAAGTGGCAGTGATCCCAGCATGTGGACAGCCAGAGGCCCCTTCAGAAGAGACAGGT
  GGAGCAGTGAGGATGAGGAGGCTGCAGGGCCATCACAGGCTCTCTCCCCTCTACTTTCTGATACGCGCAA
  AATTGTTTCTGAAGGAGAACTAGATCAGTTGGCTCAGATTCGGCCATTAATATTCAATTTTCATGAGCAG
  ACAGCCATCAAGGATTGTTTGAAAATCCTTGAGGAAAAAACAGCAGCGTATGATATCATGCAGGAATTTA
  TGGCTTTAGAACTTAAGAATCTGCCTGGTGAGTTCAACTCTGGGAATCAACCAAGCAACAGAGAAAAAAA
  CAGATACCGAGATATTCTTCCATTTCAACATCATGGATATAGTGGCCCAAATGAGAGAACAACGTTCTGG
  CATGGTTCAAACGAAGGAGCAGTATCACTTTTGTTACGATATTGTGCT
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC223995 protein sequence
  Red=Cloning site Green=Tags(s)
  
  MSSPRDFRAEPVNDYEGNDSEAEDLNFRETLPSSSQENTPRSKVFENKVNSEKVKLSLRNFPHNDYEDVF
  EEPSESGSDPSMWTARGPFRRDRWSSEDEEAAGPSQALSPLLSDTRKIVSEGELDQLAQIRPLIFNFHEQ
  TAIKDCLKILEEKTAAYDIMQEFMALELKNLPGEFNSGNQPSNREKNRYRDILPFQHHGYSGPNERTTFW
  HGSNEGAVSLLLRYCA
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001042387
• ORF Size: 678 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001042387.1, NP_001035846.1
• RefSeq Size: 2478
• RefSeq ORF: 680
• Locus ID: 653129
• Protein Families: Druggable Genome
• MW: 25.9 kDa
• Gene Summary: The product of this gene belongs to the family of classical tyrosine-specific protein tyrosine phosphatases. Many protein tyrosine phosphatases have been shown to regulate fundamental cellular processes and several are mutated in human diseases. Chromosome 10q contains a segmental duplication resulting in multiple copies of the protein tyrosine phosphatase, non-receptor type 20 gene. The two nearly identical copies are designated as PTPN20A and PTPN20B. A third copy is only partially duplicated and contains a pseudogene, designated as PTPN20C. This gene encodes the more centromeric copy, PTPN20A. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]