ABCC9 (NM_005691) Human Tagged ORF Clone

CAT#: RC224378

ABCC9 (Myc-DDK-tagged)-Human ATP-binding cassette, sub-family C (CFTR/MRP), member 9 (ABCC9), transcript variant SUR2A

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: ABCC9
• Synonyms: ABC37; ATFB12; CANTU; CMD1O; SUR2
• Vector: pCMV6-AC-Myc-DDK
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC224378 representing NM_005691
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAGCCTTTCATTTTGTGGTAACAACATTTCTTCATATAATATCAACGATGGTGTACTACAAAATTCCT
  GCTTTGTGGATGCCCTCAACCTGGTCCCTCATGTCTTTCTGTTGTTTATCACTTTTCCAATATTGTTTAT
  TGGGTGGGGGAGCCAAAGCTCAAAAGTACAAATTCACCACAACACATGGCTTCATTTTCCGGGACATAAC
  CTGAGATGGATTCTTACATTCGCTCTCCTGTTTGTGCATGTCTGTGAAATAGCAGAAGGCATTGTTTCAG
  ACTCGCGGCGGGAATCAAGGCACCTCCACCTCTTTATGCCAGCCGTGATGGGATTCGTTGCCACTACAAC
  ATCGATAGTGTATTATCATAATATCGAAACATCAAATTTTCCTAAATTACTTTTAGCCCTGTTCCTGTAT
  TGGGTAATGGCCTTTATTACAAAAACAATAAAATTGGTTAAGTACTGTCAGTCTGGCTTGGACATATCAA
  ACCTGCGTTTCTGCATCACAGGCATGATGGTCATCTTGAATGGGCTCTTGATGGCTGTGGAGATCAATGT
  CATTCGAGTCAGGAGATATGTATTTTTCATGAATCCTCAGAAAGTAAAGCCTCCTGAAGACCTCCAGGAT
  CTGGGAGTGAGATTTCTTCAACCATTTGTGAATTTGCTGTCAAAAGCAACATACTGGTGGATGAACACAC
  TTATTATATCTGCTCACAAAAAGCCTATTGATCTGAAGGCAATTGGAAAATTGCCAATAGCAATGAGAGC
  AGTAACAAATTATGTTTGCCTGAAAGATGCATATGAAGAACAAAAGAAAAAAGTTGCAGATCATCCAAAT
  CGGACTCCATCTATATGGCTTGCAATGTACAGAGCTTTTGGGCGACCAATTCTACTTAGTAGCACATTCC
  GCTATCTGGCTGATTTACTGGGTTTTGCTGGACCTCTTTGTATTTCTGGAATAGTTCAGCGTGTGAATGA
  AACCCAGAATGGGACAAATAACACAACTGGAATTTCAGAAACCCTCTCATCAAAGGAATTTCTTGAAAAC
  GCTTACGTTCTAGCAGTTCTTCTCTTCTTGGCTCTTATTCTGCAAAGGACATTTTTGCAGGCTTCCTACT
  ATGTAACCATAGAGACTGGCATTAACCTCCGTGGAGCTCTGCTGGCCATGATTTATAATAAAATCCTTAG
  GCTCTCTACGTCTAACTTATCCATGGGGGAGATGACTCTGGGGCAGATCAACAACTTAGTCGCCATTGAA
  ACTAATCAACTCATGTGGTTTTTGTTCCTGTGTCCTAATCTATGGGCTATGCCTGTTCAGATCATAATGG
  GCGTGATTCTGCTCTATAATTTACTTGGATCAAGTGCATTGGTCGGTGCAGCTGTCATTGTGCTCCTTGC
  GCCAATTCAGTACTTTATTGCTACAAAGTTGGCAGAGGCTCAGAAAAGTACACTTGATTATTCCACTGAG
  AGACTCAAGAAAACAAATGAAATATTGAAAGGCATCAAACTTCTAAAATTGTATGCCTGGGAACACATTT
  TCTGCAAAAGTGTGGAGGAAACAAGAATGAAAGAACTATCTAGTCTCAAAACCTTTGCACTATATACATC
  ACTCTCCATCTTCATGAATGCAGCAATTCCCATAGCAGCTGTTCTTGCTACATTTGTGACCCATGCGTAT
  GCCAGTGGAAACAATCTGAAACCTGCAGAGGCCTTTGCTTCACTGTCTCTCTTCCATATCCTGGTCACAC
  CACTGTTCCTGCTCTCCACGGTGGTCAGATTTGCAGTCAAAGCCATCATAAGTGTTCAAAAGCTGAATGA
  GTTTCTCTTGAGTGATGAGATTGGTGACGACAGTTGGCGAACTGGTGAAAGTTCGCTTCCTTTTGAGTCC
  TGTAAGAAGCACACTGGAGTTCAGCCAAAAACTATAAACAGGAAACAGCCTGGAAGATATCACCTGGACA
  GCTATGAGCAATCAACACGGCGTCTACGTCCCGCAGAAACAGAGGACATTGCAATAAAGGTCACAAATGG
  ATACTTTTCATGGGGCAGTGGTTTAGCTACATTATCCAATATAGATATTCGAATTCCAACAGGTCAGTTA
  ACCATGATTGTGGGCCAAGTAGGATGTGGGAAGTCCTCTCTTCTCCTTGCCATCCTCGGTGAGATGCAGA
  CATTGGAAGGAAAAGTTCACTGGAGCAATGTAAATGAATCTGAGCCTTCTTTTGAAGCAACCAGAAGTAG
  GAACAGGTACTCTGTGGCATATGCAGCTCAAAAGCCTTGGCTATTAAATGCTACAGTAGAAGAAAATATT
  ACTTTTGGAAGTCCTTTTAACAAACAGAGGTACAAAGCTGTCACAGATGCCTGTTCTCTTCAGCCAGATA
  TTGACTTATTACCATTTGGAGATCAAACTGAAATTGGAGAGAGGGGCATCAACCTGAGTGGGGGACAGAG
  GCAGAGAATCTGTGTGGCACGAGCGCTGTATCAAAACACCAACATTGTCTTTTTGGATGATCCATTCTCA
  GCCCTGGACATTCACTTGAGTGATCATTTAATGCAGGAGGGGATTTTGAAATTCCTGCAAGATGACAAAA
  GGACACTCGTTCTTGTGACTCACAAATTACAGTATCTGACGCATGCTGACTGGATCATAGCCATGAAAGA
  TGGAAGTGTCCTAAGAGAAGGAACTTTGAAGGACATTCAAACCAAAGATGTTGAGCTTTATGAACACTGG
  AAAACACTTATGAATCGGCAAGATCAAGAATTAGAAAAGGATATGGAAGCTGACCAAACTACTTTAGAGA
  GGAAAACTCTCCGACGGGCCATGTATTCAAGAGAAGCCAAAGCCCAGATGGAGGACGAAGACGAAGAGGA
  AGAAGAGGAGGAAGATGAGGATGATAACATGTCCACTGTAATGAGGCTCAGGACTAAAATGCCATGGAAA
  ACCTGCTGGCGCTACCTGACATCTGGAGGATTCTTCCTGCTCATCCTGATGATTTTCTCTAAGCTTTTGA
  AGCATTCGGTCATTGTAGCTATAGACTATTGGCTGGCCACATGGACATCGGAGTACAGTATAAACAATAC
  TGGAAAAGCTGATCAGACCTACTATGTGGCTGGCTTTAGCATACTCTGTGGAGCAGGCATTTTCCTTTGC
  CTTGTTACATCCCTCACTGTAGAATGGATGGGTCTCACAGCTGCCAAAAATCTTCACCACAACCTTCTCA
  ATAAGATAATCCTTGGACCAATAAGGTTTTTTGATACCACACCCCTGGGACTGATTCTCAATCGCTTTTC
  AGCTGATACTAATATCATTGATCAGCACATCCCTCCAACCTTGGAATCTCTAACTCGCTCAACACTGCTC
  TGCCTGTCTGCCATTGGGATGATTTCTTATGCTACTCCTGTGTTCCTGGTTGCTCTCCTGCCCCTTGGTG
  TTGCCTTTTATTTTATCCAGAAATACTTTCGGGTTGCCTCTAAGGACCTCCAGGAACTTGACGATAGTAC
  CCAGCTCCCTCTGCTCTGTCACTTCTCAGAAACAGCAGAAGGACTCACCACCATTCGGGCCTTTAGGCAT
  GAAACCAGATTTAAACAACGTATGCTGGAACTGACGGATACAAACAACATTGCCTACTTATTTCTCTCAG
  CTGCCAACAGATGGCTGGAGGTCAGGACGGATTATCTGGGAGCTTGCATTGTCCTCACTGCATCTATAGC
  ATCCATTAGTGGGTCTTCGAATTCTGGATTGGTAGGCTTGGGTCTTCTGTATGCACTTACGATAACCAAT
  TATTTGAATTGGGTTGTGAGGAACTTGGCTGACCTGGAGGTCCAGATGGGTGCAGTGAAGAAGGTGAACA
  GTTTCCTGACTATGGAGTCAGAGAACTATGAAGGCACAATGGATCCTTCTCAAGTTCCAGAACATTGGCC
  ACAAGAAGGGGAGATCAAGATACATGATCTGTGTGTCAGATATGAAAATAATCTGAAACCTGTTCTTAAG
  CACGTCAAGGCTTACATCAAACCTGGACAAAAGGTGGGCATATGTGGTCGCACTGGCAGTGGGAAATCAT
  CGTTATCTCTGGCTTTCTTCAGAATGGTTGATATATTTGATGGAAAAATTGTCATTGATGGGATAGACAT
  TTCCAAATTACCACTGCACACACTACGTTCTAGACTTTCAATCATTCTGCAGGATCCAATACTATTCAGT
  GGTTCCATTAGATTTAATTTAGATCCAGAGTGCAAATGCACAGATGACAGACTCTGGGAAGCCTTAGAAA
  TTGCTCAGCTGAAGAATATGGTCAAATCTCTACCTGGAGGTCTAGATGCGGTTGTCACTGAAGGTGGGGA
  GAATTTTAGCGTTGGACAGAGACAGCTATTTTGCCTTGCCAGGGCCTTTGTCCGCAAAAGCAGCATTCTT
  ATTATGGATGAGGCAACAGCTTCCATTGACATGGCCACAGAGAATATTTTGCAAAAAGTAGTAATGACAG
  CCTTTGCAGACCGGACCGTGGTGACAATAGCTCACCGTGTCTCTTCTATTATGGATGCAGGCCTTGTTTT
  AGTCTTTTCTGAGGGTATTTTAGTGGAGTGTGATACTGTCCCAAATTTGCTCGCCCACAAGAATGGCCTC
  TTTTCCACTTTGGTGATGACCAACAAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC224378 representing NM_005691
  Red=Cloning site Green=Tags(s)
  
  MSLSFCGNNISSYNINDGVLQNSCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHN
  LRWILTFALLFVHVCEIAEGIVSDSRRESRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLALFLY
  WVMAFITKTIKLVKYCQSGLDISNLRFCITGMMVILNGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQD
  LGVRFLQPFVNLLSKATYWWMNTLIISAHKKPIDLKAIGKLPIAMRAVTNYVCLKDAYEEQKKKVADHPN
  RTPSIWLAMYRAFGRPILLSSTFRYLADLLGFAGPLCISGIVQRVNETQNGTNNTTGISETLSSKEFLEN
  AYVLAVLLFLALILQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNLSMGEMTLGQINNLVAIE
  TNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGSSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTE
  RLKKTNEILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPIAAVLATFVTHAY
  ASGNNLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIISVQKLNEFLLSDEIGDDSWRTGESSLPFES
  CKKHTGVQPKTINRKQPGRYHLDSYEQSTRRLRPAETEDIAIKVTNGYFSWGSGLATLSNIDIRIPTGQL
  TMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNVNESEPSFEATRSRNRYSVAYAAQKPWLLNATVEENI
  TFGSPFNKQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFS
  ALDIHLSDHLMQEGILKFLQDDKRTLVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELYEHW
  KTLMNRQDQELEKDMEADQTTLERKTLRRAMYSREAKAQMEDEDEEEEEEEDEDDNMSTVMRLRTKMPWK
  TCWRYLTSGGFFLLILMIFSKLLKHSVIVAIDYWLATWTSEYSINNTGKADQTYYVAGFSILCGAGIFLC
  LVTSLTVEWMGLTAAKNLHHNLLNKIILGPIRFFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLL
  CLSAIGMISYATPVFLVALLPLGVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLTTIRAFRH
  ETRFKQRMLELTDTNNIAYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLGLLYALTITN
  YLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQEGEIKIHDLCVRYENNLKPVLK
  HVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPILFS
  GSIRFNLDPECKCTDDRLWEALEIAQLKNMVKSLPGGLDAVVTEGGENFSVGQRQLFCLARAFVRKSSIL
  IMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVSSIMDAGLVLVFSEGILVECDTVPNLLAHKNGL
  FSTLVMTNK
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_005691
• ORF Size: 4647 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_005691.1, NM_005691.2, NM_005691.3, NP_005682.2
• RefSeq Size: 4670
• RefSeq ORF: 4650
• Locus ID: 10060
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: ABC transporters
• MW: 174 kDa
• Gene Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extra-pancreatic ATP-sensitive potassium channels. Mutations in this gene are associated with cardiomyopathy dilated type 1O. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2011]