ABCC9 (NM_005691) Human Untagged Clone

CAT#: SC316627

ABCC9 (untagged)-Human ATP-binding cassette, sub-family C (CFTR/MRP), member 9 (ABCC9), transcript variant SUR2A

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ABCC9
• Synonyms: ABC37; ATFB12; CANTU; CMD1O; SUR2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_005691, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGCCTTTCATTTTGTGGTAACAACATTTCTTCATATAATATCAACGATGGTGTACTACAAAATTCCT
  GCTTTGTGGATGCCCTCAACCTGGTCCCTCATGTCTTTCTGTTGTTTATCACTTTTCCAATATTGTTTAT
  TGGGTGGGGGAGCCAAAGCTCAAAAGTACAAATTCACCACAACACATGGCTTCATTTTCCGGGACATAAC
  CTGAGATGGATTCTTACATTCGCTCTCCTGTTTGTGCATGTCTGTGAAATAGCAGAAGGCATTGTTTCAG
  ACTCGCGGCGGGAATCAAGGCACCTCCACCTCTTTATGCCAGCCGTGATGGGATTCGTTGCCACTACAAC
  ATCGATAGTGTATTATCATAATATCGAAACATCAAATTTTCCTAAATTACTTTTAGCCCTGTTCCTGTAT
  TGGGTAATGGCCTTTATTACAAAAACAATAAAATTGGTTAAGTACTGTCAGTCTGGCTTGGACATATCAA
  ACCTGCGTTTCTGCATCACAGGCATGATGGTCATCTTGAATGGGCTCTTGATGGCTGTGGAGATCAATGT
  CATTCGAGTCAGGAGATATGTATTTTTCATGAATCCTCAGAAAGTAAAGCCTCCTGAAGACCTCCAGGAT
  CTGGGAGTGAGATTTCTTCAACCATTTGTGAATTTGCTGTCAAAAGCAACATACTGGTGGATGAACACAC
  TTATTATATCTGCTCACAAAAAGCCTATTGATCTGAAGGCAATTGGAAAATTGCCAATAGCAATGAGAGC
  AGTAACAAATTATGTTTGCCTGAAAGATGCATATGAAGAACAAAAGAAAAAAGTTGCAGATCATCCAAAT
  CGGACTCCATCTATATGGCTTGCAATGTACAGAGCTTTTGGGCGACCAATTCTACTTAGTAGCACATTCC
  GCTATCTGGCTGATTTACTGGGTTTTGCTGGACCTCTTTGTATTTCTGGAATAGTTCAGCGTGTGAATGA
  AACCCAGAATGGGACAAATAACACAACTGGAATTTCAGAAACCCTCTCATCAAAGGAATTTCTTGAAAAC
  GCTTACGTTCTAGCAGTTCTTCTCTTCTTGGCTCTTATTCTGCAAAGGACATTTTTGCAGGCTTCCTACT
  ATGTAACCATAGAGACTGGCATTAACCTCCGTGGAGCTCTGCTGGCCATGATTTATAATAAAATCCTTAG
  GCTCTCTACGTCTAACTTATCCATGGGGGAGATGACTCTGGGGCAGATCAACAACTTAGTCGCCATTGAA
  ACTAATCAACTCATGTGGTTTTTGTTCCTGTGTCCTAATCTATGGGCTATGCCTGTTCAGATCATAATGG
  GCGTGATTCTGCTCTATAATTTACTTGGATCAAGTGCATTGGTCGGTGCAGCTGTCATTGTGCTCCTTGC
  GCCAATTCAGTACTTTATTGCTACAAAGTTGGCAGAGGCTCAGAAAAGTACACTTGATTATTCCACTGAG
  AGACTCAAGAAAACAAATGAAATATTGAAAGGCATCAAACTTCTAAAATTGTATGCCTGGGAACACATTT
  TCTGCAAAAGTGTGGAGGAAACAAGAATGAAAGAACTATCTAGTCTCAAAACCTTTGCACTATATACATC
  ACTCTCCATCTTCATGAATGCAGCAATTCCCATAGCAGCTGTTCTTGCTACATTTGTGACCCATGCGTAT
  GCCAGTGGAAACAATCTGAAACCTGCAGAGGCCTTTGCTTCACTGTCTCTCTTCCATATCCTGGTCACAC
  CACTGTTCCTGCTCTCCACGGTGGTCAGATTTGCAGTCAAAGCCATCATAAGTGTTCAAAAGCTGAATGA
  GTTTCTCTTGAGTGATGAGATTGGTGACGACAGTTGGCGAACTGGTGAAAGTTCGCTTCCTTTTGAGTCC
  TGTAAGAAGCACACTGGAGTTCAGCCAAAAACTATAAACAGGAAACAGCCTGGAAGATATCACCTGGACA
  GCTATGAGCAATCAACACGGCGTCTACGTCCCGCAGAAACAGAGGACATTGCAATAAAGGTCACAAATGG
  ATACTTTTCATGGGGCAGTGGTTTAGCTACATTATCCAATATAGATATTCGAATTCCAACAGGTCAGTTA
  ACCATGATTGTGGGCCAAGTAGGATGTGGGAAGTCCTCTCTTCTCCTTGCCATCCTCGGTGAGATGCAGA
  CATTGGAAGGAAAAGTTCACTGGAGCAATGTAAATGAATCTGAGCCTTCTTTTGAAGCAACCAGAAGTAG
  GAACAGGTACTCTGTGGCATATGCAGCTCAAAAGCCTTGGCTATTAAATGCTACAGTAGAAGAAAATATT
  ACTTTTGGAAGTCCTTTTAACAAACAGAGGTACAAAGCTGTCACAGATGCCTGTTCTCTTCAGCCAGATA
  TTGACTTATTACCATTTGGAGATCAAACTGAAATTGGAGAGAGGGGCATCAACCTGAGTGGGGGACAGAG
  GCAGAGAATCTGTGTGGCACGAGCGCTGTATCAAAACACCAACATTGTCTTTTTGGATGATCCATTCTCA
  GCCCTGGACATTCACTTGAGTGATCATTTAATGCAGGAGGGGATTTTGAAATTCCTGCAAGATGACAAAA
  GGACACTCGTTCTTGTGACTCACAAATTACAGTATCTGACGCATGCTGACTGGATCATAGCCATGAAAGA
  TGGAAGTGTCCTAAGAGAAGGAACTTTGAAGGACATTCAAACCAAAGATGTTGAGCTTTATGAACACTGG
  AAAACACTTATGAATCGGCAAGATCAAGAATTAGAAAAGGATATGGAAGCTGACCAAACTACTTTAGAGA
  GGAAAACTCTCCGACGGGCCATGTATTCAAGAGAAGCCAAAGCCCAGATGGAGGACGAAGACGAAGAGGA
  AGAAGAGGAGGAAGATGAGGATGATAACATGTCCACTGTAATGAGGCTCAGGACTAAAATGCCATGGAAA
  ACCTGCTGGCGCTACCTGACATCTGGAGGATTCTTCCTGCTCATCCTGATGATTTTCTCTAAGCTTTTGA
  AGCATTCGGTCATTGTAGCTATAGACTATTGGCTGGCCACATGGACATCGGAGTACAGTATAAACAATAC
  TGGAAAAGCTGATCAGACCTACTATGTGGCTGGCTTTAGCATACTCTGTGGAGCAGGCATTTTCCTTTGC
  CTTGTTACATCCCTCACTGTAGAATGGATGGGTCTCACAGCTGCCAAAAATCTTCACCACAACCTTCTCA
  ATAAGATAATCCTTGGACCAATAAGGTTTTTTGATACCACACCCCTGGGACTGATTCTCAATCGCTTTTC
  AGCTGATACTAATATCATTGATCAGCACATCCCTCCAACCTTGGAATCTCTAACTCGCTCAACACTGCTC
  TGCCTGTCTGCCATTGGGATGATTTCTTATGCTACTCCTGTGTTCCTGGTTGCTCTCCTGCCCCTTGGTG
  TTGCCTTTTATTTTATCCAGAAATACTTTCGGGTTGCCTCTAAGGACCTCCAGGAACTTGACGATAGTAC
  CCAGCTCCCTCTGCTCTGTCACTTCTCAGAAACAGCAGAAGGACTCACCACCATTCGGGCCTTTAGGCAT
  GAAACCAGATTTAAACAACGTATGCTGGAACTGACGGATACAAACAACATTGCCTACTTATTTCTCTCAG
  CTGCCAACAGATGGCTGGAGGTCAGGACGGATTATCTGGGAGCTTGCATTGTCCTCACTGCATCTATAGC
  ATCCATTAGTGGGTCTTCGAATTCTGGATTGGTAGGCTTGGGTCTTCTGTATGCACTTACGATAACCAAT
  TATTTGAATTGGGTTGTGAGGAACTTGGCTGACCTGGAGGTCCAGATGGGTGCAGTGAAGAAGGTGAACA
  GTTTCCTGACTATGGAGTCAGAGAACTATGAAGGCACAATGGATCCTTCTCAAGTTCCAGAACATTGGCC
  ACAAGAAGGGGAGATCAAGATACATGATCTGTGTGTCAGATATGAAAATAATCTGAAACCTGTTCTTAAG
  CACGTCAAGGCTTACATCAAACCTGGACAAAAGGTGGGCATATGTGGTCGCACTGGCAGTGGGAAATCAT
  CGTTATCTCTGGCTTTCTTCAGAATGGTTGATATATTTGATGGAAAAATTGTCATTGATGGGATAGACAT
  TTCCAAATTACCACTGCACACACTACGTTCTAGACTTTCAATCATTCTGCAGGATCCAATACTATTCAGT
  GGTTCCATTAGATTTAATTTAGATCCAGAGTGCAAATGCACAGATGACAGACTCTGGGAAGCCTTAGAAA
  TTGCTCAGCTGAAGAATATGGTCAAATCTCTACCTGGAGGTCTAGATGCGGTTGTCACTGAAGGTGGGGA
  GAATTTTAGCGTTGGACAGAGACAGCTATTTTGCCTTGCCAGGGCCTTTGTCCGCAAAAGCAGCATTCTT
  ATTATGGATGAGGCAACAGCTTCCATTGACATGGCCACAGAGAATATTTTGCAAAAAGTAGTAATGACAG
  CCTTTGCAGACCGGACCGTGGTGACAATAGCTCACCGTGTCTCTTCTATTATGGATGCAGGCCTTGTTTT
  AGTCTTTTCTGAGGGTATTTTAGTGGAGTGTGATACTGTCCCAAATTTGCTCGCCCACAAGAATGGCCTC
  TTTTCCACTTTGGTGATGACCAACAAGTAG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005691 unedited
  TCCTTCAGTGCTATCTTGTATACGACTCCTATAGGGCGGCCGCGAATCGGCACGAGCTCA
  AGTGCACCGGCAGGGGTTTGAAGCAGCGTGAAGCTATTGCCCAAGATGTGTGGAATTTCA
  TGTAATGCATTTCGAGGAATAAAAACACTGAGGGTGCGATTCTTGCCATGAAATCGAAAA
  GTATTGTTTGTGACCATTGCTAAATCAATTATCAATGAAAGGAAAGAAAGAAAAGAGTAA
  ACCATATAAGAAGAAATGAGCCTTTCATTTTGTGGTAACAACATTTCTTCATATAATATC
  AACGATGGTGTACTACAAAATTCCTGCTTTGTGGATGCCCTCAACCTGGTCCCTCATGTC
  TTTCTGTTGTTTATCACTTTTCCAATATTGTTTATTGGGTGGGGGAGCCAAAGCTCAAAA
  GTACAAATTCACCACAACACATGGCTTCATTTTCCGGGACATAACCTGAGATGGATTCTT
  ACATTCGCTCTCCTGTTTGTGCATGTCTGTGAAATAGCAGAAGGCATTGTTTCAGACTCG
  CGGCGGGAATCAAGGCACCTCCACCTCTTTATGCCAGCCGTGATGGGATTCGTTGCCACT
  ACAACATCGATAGTGTATTATCATAATATCGAAACATCAAATTTTCCTAAATTACTTTTA
  GCCCTGTTCCTGTATTGGGTAATGGCCTTTATTACAAAAACAATAAAATTGGTTAAGTAC
  TGTCAGTCTGGCTTGGACATATCAAACCTGCGTTTCTGCATCACAGGCATGATGGTCATC
  TTGAATGGGCTCTTGATGGCTGTGGAGATCAATGTCATTCGAGTCAGAGATATTGTATTT
  TTTCATGAATCCTCAGAAAGTAAAGCCTCTGAAGAACCTCAGGATTCTGGGAGGTGGAGA
  TTTCTTCACCCAATTTTGGTGAAATTTTGCTTGTCCAAAGGCAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005691 unedited
  CCACGGATGGCCACCTTACACGGCCTCTAACAGCACTGGGGAGGGGTCACAGGGTATGCC
  ACCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGACTACTTGTTGGT
  CATCACCAAAGTGGAAAAGAGGCCATTCTTGTGGGCGAGCAAATTTGGGACAGTATCACA
  CTCCACTAAAATACCCTCAGAAAAGACTAAAACAAGGCCTGCATCCATAATAGAAGAGAC
  ACGGTGAGCTATTGTCACCACGGTCCGGTCTGCAAAGGCTGTCATTACTACTTTTTGCAA
  AATATTCTCTGTGGCCATGTCAATGGAAGCTGTTGCCTCATCCATAATAAGAATGCTGCT
  TTTGCGGACAAAGGCCCTGGCAAGGCAAAATAGCTGTCTCTGTCCAACGCTAAAATTCTC
  CCCACCTTCAGTGACAACCGCATCTAGACCTCCAGGTAGAGATTTGACCATATTCTTCAG
  CTGAGCAATTTCTAAGGCTTCCCAGAGTCTGTCATCTGTGCATTTGCACTCTGGATCTAA
  ATTAAATCTAATGGAACCACTGAATAGTATTGGATCCTGCAGAATGATTGAAAGTCTAGA
  ACGTAGTGTGTGCAGTGGTAATTTGGAAATGTCTATCCCATCAATGACAATTTTTCCATC
  AAATATATCAACCATTCTGAAGAAAGCCAGAGATAACGATGATTTCCCACTGCCAGTGCG
  ACCACATATGCCCACCTTTTGTCCAGGTTTGATGTAAGCCTTGACGTGCTTAAGAACAGG
  TTTCAGATTATTTTCATATCTGACACACAGATCATGTATCTTGATCTCCCTTCTTGTGGC
  CAATGTTCTGGAACTTGAGAAGGATCCATTTGTGCCTTTCATAGTTCTTCTGACTCCATA
  GTTCAGGGAAACTGTTCACCTTCTTTCCCATGCACCCAA
  
• Restriction Sites: Please inquire
• ACCN: NM_005691
• ORF Size: 4650 bp
• Insert Size: 4900
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_005691.2, NP_005682.2
• RefSeq Size: 4670
• RefSeq ORF: 4650
• Locus ID: 10060
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: ABC transporters
• Gene Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extra-pancreatic ATP-sensitive potassium channels. Mutations in this gene are associated with cardiomyopathy dilated type 1O. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2011]
  Transcript Variant: This variant (SUR2A) uses an alternate 3' coding exon (exon 38A), compared to variant SUR2B, which uses exon 38B. The encoded isoform (SUR2A) has an alternate 38-amino acid C-terminus, but is the same length as isoform SUR2B. There are no full-length transcripts representing this variant in human; it is supported by partial transcript alignments, by full-length transcript alignments from the homologous mouse and rat genes, and by RT-PCR analysis in PMID:11054556. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.