PARN (NM_001134477) Human Tagged ORF Clone
CAT#: RC225978L3
- LentiORF®
Lenti-ORF clone of PARN (Myc-DDK-tagged)-Human poly(A)-specific ribonuclease (deadenylation nuclease) (PARN), transcript variant 2
"NM_001134477" in other vectors (4)
Product Images
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Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | PARN |
Synonyms | DAN; DKCB6; PFBMFT4 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC225978).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_001134477 |
ORF Size | 1920 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001134477.2, NP_001127949.1 |
RefSeq Size | 3000 bp |
RefSeq ORF | 1737 bp |
Locus ID | 5073 |
Cytogenetics | 16p13.12 |
Protein Families | Transcription Factors |
Protein Pathways | RNA degradation |
MW | 73.5 kDa |
Gene Summary | 'The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC325208 | PARN (untagged)-Human poly(A)-specific ribonuclease (deadenylation nuclease) (PARN), transcript variant 2 |
USD 760.00 |
|
RC225978 | PARN (Myc-DDK-tagged)-Human poly(A)-specific ribonuclease (deadenylation nuclease) (PARN), transcript variant 2 |
USD 670.00 |
|
RG225978 | PARN (GFP-tagged) - Human poly(A)-specific ribonuclease (deadenylation nuclease) (PARN), transcript variant 2 |
USD 740.00 |
|
RC225978L4 | Lenti-ORF clone of PARN (mGFP-tagged)-Human poly(A)-specific ribonuclease (deadenylation nuclease) (PARN), transcript variant 2 |
USD 870.00 |
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