DCTN4 (NM_001135644) Human Tagged ORF Clone

CAT#: RC226539

DCTN4 (Myc-DDK-tagged)-Human dynactin 4 (p62) (DCTN4), transcript variant 3

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: DCTN4
• Synonyms: DYN4; P62
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC226539 representing NM_001135644
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCCATCGGCTGAAGCCAAACTAAAAAAGAATAGATGTGCCAATTGTTTTGACTGTCCTGGCTGCATGC
  ACACCCTCTCTACTCGGGCCACGAGCATCTCCACACAGCTTCCAGATGACCCAGCCAAGACCACCATGAA
  GAAAGCCTATTACCTGGCATGTGGATTTTGTCGCTGGACGTCTAGAGATGTGGGCATGGCAGACAAATCT
  GTAGCTAGTGGCGGTTGGCAGGAACCTGAAAATCCTCACACACAACGGATGAACAAATTGATTGAATATT
  ACCAGCAGCTTGCTCAGAAAGAGAAGGTTGAGCGAGATCGCAAGAAACTGGCACGACGTAGAAACTATAT
  GCCTCTGGCTTTTTCGGACAAATATGGTCTTGGAACCAGGCTTCAGCGACCACGAGCTGGTGCATCCATC
  AGTACCCTTGCCGGACTTTCCCTTAAAGAAGGAGAGGATCAGAAAGAGATAAAGATTGAGCCAGCTCAGG
  CTGTGGATGAAGTGGAACCTCTACCTGAAGACTATTATACAAGACCAGTAAATTTAACAGAGGTAACAAC
  CCTTCAGCAGCGTCTGTTACAGCCTGACTTCCAGCCAGTCTGTGCTTCACAGCTCTATCCTCGCCACAAA
  CATCTTCTGATCAAACGGTCCCTGCGCTGCCGTAAATGTGAACATAATTTGAGCAAGCCAGAATTTAACC
  CAACGTCAATCAAATTCAAAATCCAGCTGGTCGCTGTCAATTATATTCCAGAAGTGAGAATCATGTCAAT
  TCCCAACCTTCGCTACATGAAGGAGAGCCAGGTCCTCCTGACTCTTACAAATCCAGTTGAGAACCTCACC
  CATGTGACTCTCTTCGAGTGTGAGGAGGGGGACCCTGATGATATCAACAGCACTGCTAAGGTGGTGGTGC
  CTCCCAAAGAGCTCGTTTTAGCTGGCAAGGATGCAGCAGCAGAGTACGATGAGTTGGCAGAACCTCAAGA
  CTTTCAGGACGATCCTGACATTATAGCCTTCAGAAAGGCCAACAAAGTGGGTATTTTCATCAAAGTTACA
  CCACAGCGTGAGGAGGGTGAAGTGACCGTGTGCTTCAAGATGAAGCATGATTTTAAAAACCTGGCAGCCC
  CCATTCGCCCCATTGAAGAAAGTGACCAGGGAACAGAAGTCATCTGGCTCACCCAGCATGTGGAACTTAG
  CTTGGGCCCACTTCTTCCT
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC226539 representing NM_001135644
  Red=Cloning site Green=Tags(s)
  
  MPSAEAKLKKNRCANCFDCPGCMHTLSTRATSISTQLPDDPAKTTMKKAYYLACGFCRWTSRDVGMADKS
  VASGGWQEPENPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSDKYGLGTRLQRPRAGASI
  STLAGLSLKEGEDQKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPVCASQLYPRHK
  HLLIKRSLRCRKCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLT
  HVTLFECEEGDPDDINSTAKVVVPPKELVLAGKDAAAEYDELAEPQDFQDDPDIIAFRKANKVGIFIKVT
  PQREEGEVTVCFKMKHDFKNLAAPIRPIEESDQGTEVIWLTQHVELSLGPLLP
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001135644
• ORF Size: 1209 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001135644.1, NP_001129116.1
• RefSeq Size: 4105
• RefSeq ORF: 1212
• Locus ID: 51164
• Protein Pathways: Huntington's disease
• MW: 45.8 kDa
• Gene Summary: Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton. [UniProtKB/Swiss-Prot Function]