DCTN4 (NM_001135644) Human Untagged Clone

CAT#: SC325054

DCTN4 (untagged)-Human dynactin 4 (p62) (DCTN4), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DCTN4
• Synonyms: DYN4; P62
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001135644, the custom clone sequence may differ by one or more nucleotides
  ATGCCATCGGCTGAAGCCAAACTAAAAAAGAATAGATGTGCCAATTGTTTTGACTGTCCT
  GGCTGCATGCACACCCTCTCTACTCGGGCCACGAGCATCTCCACACAGCTTCCAGATGAC
  CCAGCCAAGACCACCATGAAGAAAGCCTATTACCTGGCATGTGGATTTTGTCGCTGGACG
  TCTAGAGATGTGGGCATGGCAGACAAATCTGTAGCTAGTGGCGGTTGGCAGGAACCTGAA
  AATCCTCACACACAACGGATGAACAAATTGATTGAATATTACCAGCAGCTTGCTCAGAAA
  GAGAAGGTTGAGCGAGATCGCAAGAAACTGGCACGACGTAGAAACTATATGCCTCTGGCT
  TTTTCGGACAAATATGGTCTTGGAACCAGGCTTCAGCGACCACGAGCTGGTGCATCCATC
  AGTACCCTTGCCGGACTTTCCCTTAAAGAAGGAGAGGATCAGAAAGAGATAAAGATTGAG
  CCAGCTCAGGCTGTGGATGAAGTGGAACCTCTACCTGAAGACTATTATACAAGACCAGTA
  AATTTAACAGAGGTAACAACCCTTCAGCAGCGTCTGTTACAGCCTGACTTCCAGCCAGTC
  TGTGCTTCACAGCTCTATCCTCGCCACAAACATCTTCTGATCAAACGGTCCCTGCGCTGC
  CGTAAATGTGAACATAATTTGAGCAAGCCAGAATTTAACCCAACGTCAATCAAATTCAAA
  ATCCAGCTGGTCGCTGTCAATTATATTCCAGAAGTGAGAATCATGTCAATTCCCAACCTT
  CGCTACATGAAGGAGAGCCAGGTCCTCCTGACTCTTACAAATCCAGTTGAGAACCTCACC
  CATGTGACTCTCTTCGAGTGTGAGGAGGGGGACCCTGATGATATCAACAGCACTGCTAAG
  GTGGTGGTGCCTCCCAAAGAGCTCGTTTTAGCTGGCAAGGATGCAGCAGCAGAGTACGAT
  GAGTTGGCAGAACCTCAAGACTTTCAGGACGATCCTGACATTATAGCCTTCAGAAAGGCC
  AACAAAGTGGGTATTTTCATCAAAGTTACACCACAGCGTGAGGAGGGTGAAGTGACCGTG
  TGCTTCAAGATGAAGCATGATTTTAAAAACCTGGCAGCCCCCATTCGCCCCATTGAAGAA
  AGTGACCAGGGAACAGAAGTCATCTGGCTCACCCAGCATGTGGAACTTAGCTTGGGCCCA
  CTTCTTCCT
  
• Restriction Sites: Please inquire
• ACCN: NM_001135644
• ORF Size: 1212 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001135644.1, NP_001129116.1
• RefSeq Size: 4105
• RefSeq ORF: 1212
• Locus ID: 51164
• Protein Pathways: Huntington's disease
• Gene Summary: Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton. [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence and lacks an alternate in-frame exon compared to variant 1. The resulting isoform (c) is shorter at the N-terminus and lacks a 7 aa internal segment compared to isoform a.