KREMEN1 (NM_032045) Human Tagged ORF Clone

CAT#: RC227108L3

Lenti-ORF clone of KREMEN1 (Myc-DDK-tagged)-Human kringle containing transmembrane protein 1 (KREMEN1), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: KREMEN1
• Synonyms: ECTD13; KREMEN; KRM1
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC227108).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_032045
• ORF Size: 1476 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_032045.3, NP_114434.3
• RefSeq ORF: 1479
• Locus ID: 83999
• Domains: KR, CUB, WSC
• Protein Families: Druggable Genome, Transmembrane
• MW: 51.9 kDa
• Gene Summary: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008]