KREMEN1 (NM_032045) Human Untagged Clone

CAT#: SC325992

KREMEN1 (untagged)-Human kringle containing transmembrane protein 1 (KREMEN1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KREMEN1
• Synonyms: ECTD13; KREMEN; KRM1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_032045 edited
  ATGGCGCCGCCAGCCGCCCGCCTCGCCCTGCTCTCCGCCGCGGCGCTCACGCTGGCGGCC
  CGGCCCGCGCCTAGCCCCGGCCTCGGCCCCGGACCCGAGTGTTTCACAGCCAATGGTGCG
  GATTATAGGGGAACACAGAACTGGACAGCACTACAAGGCGGGAAGCCATGTCTGTTTTGG
  AACGAGACTTTCCAGCATCCATACAACACTCTGAAATACCCCAACGGGGAGGGGGGCCTG
  GGTGAGCACAACTATTGCAGAAATCCAGATGGAGACGTGAGCCCCTGGTGCTATGTGGCA
  GAGCACGAGGATGGTGTCTACTGGAAGTACTGTGAGATACCTGCTTGCCAGATGCCTGGA
  AACCTTGGCTGCTACAAGGATCATGGAAACCCACCTCCTCTAACTGGCACCAGTAAAACG
  TCCAACAAACTCACCATACAAACTTGCATCAGTTTTTGTCGGAGTCAGAGGTTCAAGTTT
  GCTGGGATGGAGTCAGGCTATGCTTGCTTCTGTGGAAACAATCCTGATTACTGGAAGTAC
  GGGGAGGCAGCCAGTACCGAATGCAACAGCGTCTGCTTCGGGGATCACACCCAACCCTGT
  GGTGGCGATGGCAGGATCATCCTCTTTGATACTCTCGTGGGCGCCTGCGGTGGGAACTAC
  TCAGCCATGTCTTCTGTGGTCTATTCCCCTGACTTCCCCGACACCTATGCCACGGGGAGG
  GTCTGCTACTGGACCATCCGGGTTCCGGGGGCCTCCCACATCCACTTCAGCTTCCCCCTA
  TTTGACATCAGGGACTCGGCGGACATGGTGGAGCTTCTGGATGGCTACACCCACCGTGTC
  CTAGCCCGCTTCCACGGGAGGAGCCGCCCACCTCTGTCCTTCAACGTCTCTCTGGACTTC
  GTCATCTTGTATTTCTTCTCTGATCGCATCAATCAGGCCCAGGGATTTGCTGTTTTATAC
  CAAGCCGTCAAGGAAGAACTGCCACAGGAGAGGCCCGCTGTCAACCAGACGGTGGCCGAG
  GTGATCACGGAGCAGGCCAACCTCAGTGTCAGCGCTGCCCGGTCCTCCAAAGTCCTCTAT
  GTCATCACCACCAGCCCCAGCCACCCACCTCAGACTGTCCCAGGTAGCAATTCCTGGGCG
  CCACCCATGGGGGCTGGAAGCCACAGAGTTGAAGGATGGACAGTCTATGGTCTGGCAACT
  CTCCTCATCCTCACAGTCACAGCCATTGTAGCAAAGATACTTCTGCACGTCACATTCAAA
  TCCCATCGTGTTCCTGCTTCAGGGGACCTTAGGGATTGTCATCAACCAGGGACTTCGGGG
  GAAATCTGGAGCATTTTTTACAAGCCTTCCACTTCAATTTCCATCTTTAAGAAGAAACTC
  AAGGGTCAGAGTCAACAAGATGACCGCAATCCCCTTGCAATTCAGGACTCGGAAGTGACA
  TCACTCATCTGGTCTCAGGGGCAGCCCAGAAGTATCTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_032045
• ORF Size: 1479 bp
• Insert Size: 1500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_032045.3, NP_114434.3
• RefSeq Size: 2719
• RefSeq ORF: 1479
• Locus ID: 83999
• Domains: KR, CUB, WSC
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) represents the shorter transcript but encodes the longer isoform (2). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.