CLTCL1 (NM_001835) Human Tagged ORF Clone

CAT#: RC228687

CLTCL1 (Myc-DDK-tagged)-Human clathrin, heavy chain-like 1 (CLTCL1), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: CLTCL1
• Synonyms: CHC22; CLH22; CLTCL; CLTD
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC228687 representing NM_001835
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCGCAGATCCTCCCTGTTCGCTTTCAGGAGCACTTCCAGCTCCAAAACCTTGGAATTAATCCAGCTA
  ACATTGGATTCAGCACACTGACCATGGAATCTGACAAGTTCATATGTATCCGAGAGAAAGTTGGTGAGCA
  GGCACAGGTCACGATCATTGACATGAGTGACCCAATGGCTCCGATCCGACGGCCTATCTCTGCAGAGAGT
  GCCATCATGAATCCAGCCTCTAAGGTGATAGCTCTGAAAGCTGGGAAGACACTTCAGATCTTTAATATTG
  AGATGAAGAGTAAAATGAAGGCTCATACTATGGCAGAAGAAGTGATTTTCTGGAAATGGGTTTCTGTGAA
  CACTGTTGCCTTGGTGACCGAGACCGCGGTCTACCACTGGAGCATGGAAGGTGACTCCCAGCCCATGAAG
  ATGTTTGATAGACATACCAGTCTGGTGGGCTGCCAGGTGATTCACTACCGGACTGATGAGTACCAGAAGT
  GGCTGCTGCTCGTAGGCATCTCGGCTCAGCAAAACCGTGTGGTTGGAGCAATGCAGCTCTACTCTGTGGA
  TAGGAAGGTTTCACAACCCATAGAAGGCCATGCTGCGGCTTTTGCAGAGTTCAAGATGGAGGGGAATGCC
  AAGCCTGCCACCCTTTTCTGCTTTGCTGTACGTAATCCCACAGGAGGCAAGTTGCACATCATTGAAGTTG
  GACAGCCTGCAGCGGGAAACCAACCTTTTGTAAAGAAAGCAGTAGATGTGTTTTTTCCTCCAGAGGCACA
  GAATGATTTTCCAGTGGCTATGCAGATTGGAGCTAAACATGGTGTTATTTACTTGATCACAAAGTATGGC
  TATCTTCATCTGTACGACCTAGAGTCTGGCGTGTGCATCTGCATGAACCGTATTAGTGCTGACACAATAT
  TTGTCACTGCTCCACACAAACCAACCTCTGGAATTATTGGTGTCAACAAAAAGGGACAGGTACTGTCAGT
  TTGTGTTGAGGAAGATAACATTGTGAATTATGCAACCAACGTGCTTCAGAATCCAGACCTTGGTCTGCGT
  TTGGCCGTTCGTAGTAACCTGGCTGGGGCAGAGAAGTTGTTTGTGAGAAAATTCAATACCCTCTTTGCAC
  AGGGCAGCTATGCTGAAGCCGCCAAAGTTGCAGCGTCTGCACCAAAGGGAATCCTGCGTACCAGAGAGAC
  GGTCCAGAAATTCCAGAGTATACCCGCTCAGTCTGGCCAGGCTTCTCCATTGCTGCAGTACTTCGGAATC
  CTGCTCGACCAGGGTCAGCTCAATAAACTTGAATCCTTAGAACTTTGCCATCTGGTTCTTCAGCAGGGGC
  GTAAGCAACTCCTAGAGAAGTGGCTGAAAGAAGATAAGCTGGAGTGCTCAGAGGAGCTCGGAGACTTGGT
  CAAAACCACTGACCCCATGCTCGCTCTGAGTGTGTACCTTCGGGCAAATGTGCCAAGCAAAGTGATCCAG
  TGTTTTGCAGAAACAGGCCAATTCCAGAAAATTGTGCTCTATGCCAAAAAGGTTGGGTACACCCCAGACT
  GGATCTTTCTGCTGAGGGGTGTAATGAAGATCAGTCCGGAACAGGGCCTGCAGTTTTCTCGAATGCTAGT
  GCAGGACGAGGAGCCGCTGGCCAACATTAGCCAGATTGTGGACATTTTCATGGAAAACAGTTTAATTCAG
  CAGTGTACTTCCTTCTTATTGGATGCCTTGAAGAATAATCGCCCAGCTGAGGGACTCCTGCAGACATGGC
  TGTTGGAGATGAACCTTGTTCATGCACCCCAGGTTGCAGATGCCATCCTTGGAAATAAAATGTTTACTCA
  TTACGACCGGGCCCACATTGCCCAGCTCTGTGAGAAGGCAGGCCTCCTGCAGCAAGCACTGGAGCACTAC
  ACCGACCTCTATGACATCAAGAGGGCTGTGGTCCACACTCACCTCCTCAATCCCGAGTGGCTTGTCAATT
  TCTTTGGCTCCTTATCGGTGGAGGATTCTGTGGAGTGTCTGCATGCCATGCTGTCTGCTAACATCAGACA
  GAACCTTCAGCTGTGTGTGCAGGTGGCCTCTAAGTACCACGAGCAGCTGGGCACGCAGGCCCTGGTGGAG
  CTCTTTGAATCCTTCAAGAGTTACAAAGGCCTCTTCTACTTCCTGGGCTCAATCGTGAACTTCAGCCAAG
  ACCCAGATGTGCATCTGAAATACATTCAGGCTGCCTGTAAGACAGGGCAGATCAAGGAGGTGGAGAGGAT
  ATGCCGAGAGAGCAGCTGCTACAACCCAGAGCGTGTGAAGAACTTCCTGAAGGAGGCCAAGCTCACAGAC
  CAGCTTCCCCTCATCATCGTGTGTGATCGTTTTGGCTTTGTCCATGACCTTGTCCTATATTTATACCGCA
  ACAACCTGCAGAGGTACATTGAGATCTACGTGCAGAAGGTCAACCCTAGCCGGACCCCAGCTGTGATTGG
  AGGGCTGCTTGATGTGGATTGTTCTGAGGAAGTGATTAAACACTTAATCATGGCAGTGAGAGGACAGTTC
  TCTACTGATGAGTTGGTGGCTGAAGTAGAAAAAAGAAATAGGCTCAAGCTGCTGCTTCCCTGGCTGGAGT
  CCCAGATTCAGGAAGGCTGTGAGGAGCCTGCCACTCACAATGCACTGGCTAAAATCTACATCGACAGCAA
  CAACAGCCCCGAGTGCTTCCTGAGAGAGAATGCCTACTATGACAGCAGCGTGGTGGGCCGCTACTGTGAG
  AAGCGAGACCCCCATCTGGCCTGTGTTGCCTATGAGCGGGGGCAGTGTGACCTTGAGCTCATCAAGGTGT
  GCAATGAGAATTCTCTGTTCAAAAGCGAGGCCCGCTACCTGGTATGCAGAAAGGATCCGGAGCTCTGGGC
  TCACGTCCTTGAGGAGACCAACCCATCCAGGAGACAGCTAATTGACCAGGTGGTACAGACAGCATTGTCA
  GAAACACGGGATCCTGAAGAGATTTCGGTCACTGTCAAAGCCTTTATGACAGCCGACCTGCCTAATGAAC
  TGATTGAACTGCTGGAGAAGATAGTTCTGGATAACTCTGTCTTCAGCGAGCACAGGAATCTACAGAATCT
  GTTGATCCTGACTGCCATCAAGGCAGACCGCACACGGGTCATGGAGTACATCAGCCGCCTGGACAACTAT
  GACGCACTGGACATCGCGAGCATCGCTGTCAGCAGCGCACTGTATGAGGAGGCCTTCACCGTTTTCCACA
  AGTTTGATATGAATGCCTCAGCAATCCAGGTCCTGATCGAGCACATTGGAAACCTGGACCGGGCATATGA
  GTTTGCGGAGAGATGCAATGAGCCTGCTGTGTGGAGTCAGCTGGCCCAAGCCCAGCTCCAGAAAGATTTG
  GTGAAGGAAGCCATCAACTCCTATATCAGAGGGGACGACCCTTCCTCTTACCTGGAAGTTGTTCAGTCAG
  CCAGCAGGAGCAACAACTGGGAGGATCTAGTTAAATTTCTGCAGATGGCCAGGAAAAAGGGCCGTGAGTC
  CTATATAGAGACTGAACTTATTTTTGCCTTGGCTAAAACCAGCCGTGTTTCTGAGCTAGAAGATTTTATT
  AATGGACCCAACAATGCCCACATCCAGCAGGTTGGAGACCGCTGTTACGAGGAGGGAATGTACGAGGCTG
  CCAAGCTGCTCTATAGCAATGTTTCTAACTTTGCCCGCCTGGCTTCCACCTTGGTTCACCTCGGTGAGTA
  TCAGGCAGCAGTGGACAACAGCCGCAAGGCCAGCAGCACCCGGACGTGGAAGGAGGTGTGCTTTGCCTGC
  ATGGATGGACAAGAGTTCCGCTTCGCACAGCTGTGTGGTCTTCACATCGTCATTCATGCAGATGAGCTGG
  AGGAGCTGATGTGCTATTACCAGGATCGTGGCTACTTTGAGGAGCTGATCTTGCTGTTGGAAGCGGCCCT
  GGGCCTGGAGCGGGCCCACATGGGCATGTTCACTGAGCTGGCCATCCTCTACTCCAAATTCAAGCCACAG
  AAGATGCTGGAGCATCTGGAGCTTTTCTGGTCCCGTGTCAACATCCCAAAGGTGCTGAGGGCTGCAGAGC
  AGGCACACCTGTGGGCTGAGCTGGTGTTCCTCTATGACAAGTACGAGGAGTATGACAATGCTGTGCTCAC
  CATGATGAGCCACCCCACTGAGGCCTGGAAGGAGGGTCAGTTCAAGGACATCATTACCAAGGTTGCCAAC
  GTCGAGCTCTGTTACAGAGCCCTGCAGTTCTATTTGGATTACAAACCACTGCTCATCAATGACCTGCTGC
  TGGTGCTTTCACCCCGGCTGGACCACACCTGGACAGTCAGTTTCTTTTCAAAGGCAGGTCAGCTGCCCCT
  GGTGAAGCCTTACCTGCGGTCAGTCCAGAGCCACAACAACAAGAGTGTGAATGAGGCACTCAACCACCTG
  CTGACAGAGGAGGAGGACTATCAGGATGCCATGCAGCATGCTGCAGAGTCGCGGGATGCTGAGCTGGCCC
  AGAAGTTGCTGCAGTGGTTCCTGGAGGAAGGCAAGAGGGAGTGCTTCGCAGCTTGTCTCTTCACCTGCTA
  TGACCTGCTTCGCCCAGACATGGTGCTTGAGCTGGCCTGGAGGCACAACCTCGTGGACTTGGCCATGCCC
  TACTTCATCCAGGTGATGAGGGAGTACCTGAGCAAGGTGGACAAACTGGATGCCTTGGAGAGTCTGCGCA
  AGCAAGAGGAGCATGTGACAGAGCCTGCCCCTCTCGTGTTTGATTTTGATGGGCATGAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC228687 representing NM_001835
  Red=Cloning site Green=Tags(s)
  
  MAQILPVRFQEHFQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVTIIDMSDPMAPIRRPISAES
  AIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMAEEVIFWKWVSVNTVALVTETAVYHWSMEGDSQPMK
  MFDRHTSLVGCQVIHYRTDEYQKWLLLVGISAQQNRVVGAMQLYSVDRKVSQPIEGHAAAFAEFKMEGNA
  KPATLFCFAVRNPTGGKLHIIEVGQPAAGNQPFVKKAVDVFFPPEAQNDFPVAMQIGAKHGVIYLITKYG
  YLHLYDLESGVCICMNRISADTIFVTAPHKPTSGIIGVNKKGQVLSVCVEEDNIVNYATNVLQNPDLGLR
  LAVRSNLAGAEKLFVRKFNTLFAQGSYAEAAKVAASAPKGILRTRETVQKFQSIPAQSGQASPLLQYFGI
  LLDQGQLNKLESLELCHLVLQQGRKQLLEKWLKEDKLECSEELGDLVKTTDPMLALSVYLRANVPSKVIQ
  CFAETGQFQKIVLYAKKVGYTPDWIFLLRGVMKISPEQGLQFSRMLVQDEEPLANISQIVDIFMENSLIQ
  QCTSFLLDALKNNRPAEGLLQTWLLEMNLVHAPQVADAILGNKMFTHYDRAHIAQLCEKAGLLQQALEHY
  TDLYDIKRAVVHTHLLNPEWLVNFFGSLSVEDSVECLHAMLSANIRQNLQLCVQVASKYHEQLGTQALVE
  LFESFKSYKGLFYFLGSIVNFSQDPDVHLKYIQAACKTGQIKEVERICRESSCYNPERVKNFLKEAKLTD
  QLPLIIVCDRFGFVHDLVLYLYRNNLQRYIEIYVQKVNPSRTPAVIGGLLDVDCSEEVIKHLIMAVRGQF
  STDELVAEVEKRNRLKLLLPWLESQIQEGCEEPATHNALAKIYIDSNNSPECFLRENAYYDSSVVGRYCE
  KRDPHLACVAYERGQCDLELIKVCNENSLFKSEARYLVCRKDPELWAHVLEETNPSRRQLIDQVVQTALS
  ETRDPEEISVTVKAFMTADLPNELIELLEKIVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYISRLDNY
  DALDIASIAVSSALYEEAFTVFHKFDMNASAIQVLIEHIGNLDRAYEFAERCNEPAVWSQLAQAQLQKDL
  VKEAINSYIRGDDPSSYLEVVQSASRSNNWEDLVKFLQMARKKGRESYIETELIFALAKTSRVSELEDFI
  NGPNNAHIQQVGDRCYEEGMYEAAKLLYSNVSNFARLASTLVHLGEYQAAVDNSRKASSTRTWKEVCFAC
  MDGQEFRFAQLCGLHIVIHADELEELMCYYQDRGYFEELILLLEAALGLERAHMGMFTELAILYSKFKPQ
  KMLEHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAVLTMMSHPTEAWKEGQFKDIITKVAN
  VELCYRALQFYLDYKPLLINDLLLVLSPRLDHTWTVSFFSKAGQLPLVKPYLRSVQSHNNKSVNEALNHL
  LTEEEDYQDAMQHAAESRDAELAQKLLQWFLEEGKRECFAACLFTCYDLLRPDMVLELAWRHNLVDLAMP
  YFIQVMREYLSKVDKLDALESLRKQEEHVTEPAPLVFDFDGHE
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001835
• ORF Size: 4749 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001835.2, NM_001835.3, NP_001826.3
• RefSeq ORF: 4752
• Locus ID: 8218
• Protein Families: Druggable Genome
• Protein Pathways: Endocytosis, Huntington's disease, Lysosome
• MW: 180.1 kDa
• Gene Summary: This gene is a member of the clathrin heavy chain family and encodes a major protein of the polyhedral coat of coated pits and vesicles. Chromosomal aberrations involving this gene are associated with meningioma, DiGeorge syndrome, and velo-cardio-facial syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]