ALIX (PDCD6IP) (NM_001162429) Human Tagged ORF Clone
CAT#: RC229034L4
- LentiORF®
Lenti-ORF clone of PDCD6IP (mGFP-tagged)-Human programmed cell death 6 interacting protein (PDCD6IP), transcript variant 2
"NM_001162429" in other vectors (4)
Product Images
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Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Symbol | PDCD6IP |
Synonyms | AIP1; ALIX; DRIP4; HP95 |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC229034).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_001162429 |
ORF Size | 2619 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001162429.2, NP_001155901.1 |
RefSeq Size | 5987 |
RefSeq ORF | 2622 |
Locus ID | 10015 |
Protein Families | Druggable Genome |
Protein Pathways | Endocytosis |
MW | 96.8 kDa |
Gene Summary | This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. [provided by RefSeq, Jan 2012] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC327669 | PDCD6IP (untagged)-Human programmed cell death 6 interacting protein (PDCD6IP) transcript variant 2 |
USD 760.00 |
|
RC229034 | PDCD6IP (Myc-DDK-tagged)-Human programmed cell death 6 interacting protein (PDCD6IP), transcript variant 2 |
USD 420.00 |
|
RG229034 | PDCD6IP (GFP-tagged) - Human programmed cell death 6 interacting protein (PDCD6IP), transcript variant 2 |
USD 460.00 |
|
RC229034L3 | Lenti-ORF clone of PDCD6IP (Myc-DDK-tagged)-Human programmed cell death 6 interacting protein (PDCD6IP), transcript variant 2 |
USD 620.00 |
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