AMMECR1 (NM_001171689) Human Tagged ORF Clone

CAT#: RC229689

AMMECR1 (Myc-DDK-tagged)-Human Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 (AMMECR1), transcript variant 3

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: AMMECR1
• Synonyms: AMMERC1; MFHIEN
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC229689 representing NM_001171689
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGTGGTGTCAGCAGAGATGTGCTGCTTTTGCTTCGATGTGCTCTACTGTCACCTGTATGGATACCAGC
  AGCCCCGGACCCCCCGATTCACCAACGAGCCCTACCCACTGTTTGTAACATGGAAGATTGGTCGAGACAA
  AAGATTACGTGGATGCATAGGTACTTTTTCTGCCATGAATTTGCATTCAGGACTCAGGGAGTACACACTT
  ACCAGTGCCCTTAAAGATAGCCGTTTTCCCCCAATGACAAGGGATGAGCTGCCACGGCTTTTCTGCTCAG
  TGTCTCTGCTCACTAACTTTGAAGATGTCTGTGATTATTTGGACTGGGAGGTGGGTGTACATGGCATTAG
  AATAGAATTCATCAATGAAAAAGGATCAAAACGCACCGCCACCTACCTACCGGAGGTTGCAAAGGAGCAA
  GGATGGGACCATATACAGACCATAGACTCCTTATTGAGGAAAGGAGGATACAAAGCTCCGATTACTAATG
  AATTCAGGAAAACCATAAAACTGACCAGGTATCGTAGTGAAAAGATGACCCTGAGCTATGCTGAATACCT
  TGCTCATCGCCAGCATCATCATTTCCAAAATGGCATTGGGCATCCCCTTCCGCCATACAACCATTATTCC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC229689 representing NM_001171689
  Red=Cloning site Green=Tags(s)
  
  MVVSAEMCCFCFDVLYCHLYGYQQPRTPRFTNEPYPLFVTWKIGRDKRLRGCIGTFSAMNLHSGLREYTL
  TSALKDSRFPPMTRDELPRLFCSVSLLTNFEDVCDYLDWEVGVHGIRIEFINEKGSKRTATYLPEVAKEQ
  GWDHIQTIDSLLRKGGYKAPITNEFRKTIKLTRYRSEKMTLSYAEYLAHRQHHHFQNGIGHPLPPYNHYS
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001171689
• ORF Size: 630 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001171689.1, NP_001165160.1
• RefSeq ORF: 633
• Locus ID: 9949
• Protein Families: Druggable Genome
• MW: 25 kDa
• Gene Summary: The exact function of this gene is not known, however, submicroscopic deletion of the X chromosome including this gene, COL4A5, and FACL4 genes, result in a contiguous gene deletion syndrome, the AMME complex (Alport syndrome, mental retardation, midface hypoplasia, and elliptocytosis). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]