Adracalin (AAAS) (NM_001173466) Human Tagged ORF Clone

CAT#: RC230210L2

Lenti-ORF clone of AAAS (mGFP-tagged)-Human achalasia, adrenocortical insufficiency, alacrimia (AAAS), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: AAAS
• Synonyms: AAA; AAASb; ADRACALA; ADRACALIN; ALADIN; GL003
• Vector: pLenti-C-mGFP
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC230210).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_001173466
• ORF Size: 1539 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001173466.1, NP_001166937.1
• RefSeq ORF: 1542
• Locus ID: 8086
• MW: 56.3 kDa
• Gene Summary: The protein encoded by this gene is a member of the WD-repeat family of regulatory proteins and may be involved in normal development of the peripheral and central nervous system. The encoded protein is part of the nuclear pore complex and is anchored there by NDC1. Defects in this gene are a cause of achalasia-addisonianism-alacrima syndrome (AAAS), also called triple-A syndrome or Allgrove syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]