TCTN1 (NM_001173975) Human Tagged ORF Clone

CAT#: RC230238

TCTN1 (Myc-DDK-tagged)-Human tectonic family member 1 (TCTN1), transcript variant 4

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: TCTN1
• Synonyms: JBTS13; TECT1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC230238 representing NM_001173975
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTGCCAGCTCCTGGAGTCCACAGTGATCCAACCTCAAGGGGACAGCCCCGTTGCTGTTCTCTGTGTCT
  GTGACTTATCCCCAGCACAGTGTGACATCAACTGCTGCTGTGATCCCGACTGCAGCTCCGTGGATTTCAG
  TGTCTTTTCTGCCTGCTCAGTTCCAGTTGTCACGGGCGACAGCCAGTTTTGTAGTCAAAAAGCAGTCATC
  TATTCATTGAATTTTACAGCAAACCCACCTCAAAGAGTATTTGAACTTGTTGACCAGATTAATCCATCTA
  TTTTCTGCATTCATATTACAAACTATAAACCTGCATTATCCTTTATTAATCCAGAAGTACCTGATGAAAA
  CAATTTTGATACATTGATGAAAACATCTGATGGTTTTACATTGAATGCTGAATCATATGTTTCCTTCACA
  ACCAAACTGGATATTCCTACTGCTGCTAAATATGAGTATGGGGTTCCTCTGCAGACTTCAGATTCGTTTC
  TGAGATTTCCTTCGTCCCTGACATCATCTCTGTGCACTGATAATAACCCTGCAGCGTTTCTGGTGAACCA
  GGCTGTTAAGTGCACCAGAAAAATAAATTTAGAACAGTGTGAAGAAATTGAAGCCCTCAGCATGGCTTTT
  TACAGCAGCCCGGAAATTCTGAGGGTACCTGATTCAAGAAAAAAGGTCCCTATCACTGTTCAGTCCATCG
  TCATTCAGTCTCTAAATAAAACGCTCACCCGACGGGAGGACACTGATGTGCTGCAGCCGACTCTCGTCAA
  CGCTGGACACTTTAGCCTTTGCGTGAATGTTGTTCTTGAGGTAAAGTACAGCCTCACATACACAGATGCA
  GGTGAAGTCACCAAAGCTGATCTCTCATTCGTTCTGGGGACAGTTAGCAGCGTAGTGGTCCCACTGCAGC
  AAAAGTTTGAAATTCATTTTCTTCAGGAAAATACCCAGCCAGTCCCTCTCAGTGGAAACCCTGGTTATGT
  CGTGGGGCTCCCATTAGCTGCTGGATTCCAGCCTCATAAGGGGTCTGGGATTATTCAGACCACAAATAGA
  TATGGACAGCTTACTATTCTTCATAGCACAACTGAGCAAGACTGCTTAGCACTGGAGGGGGTCCGGACCC
  CAGTATTATTTGGTTACACTATGCAATCTGGCTGTAAACTAAGACTGACTGGAGCTCTCCCGTGTCAGCT
  CGTAGCACAGAAGGTGAAGAGCCTGCTGTGGGGCCAGGGCTTCCCAGATTACGTGGCCCCTTTTGGAAAT
  TCCCAGGCCCAGGACATGCTGGACTGGGTGCCCATCCACTTCATCACCCAGTCATTCAACAGGAAGGATT
  CCTGCCAGCTCCCAGGGGCTTTGGTTATAGAAGTGAAGTGGACTAAATACGGATCCCTGCTGAATCCACA
  GGCCAAAATAGTCAATGTAACTGCAAATCTAATTTCATCCTCCTTTCCTGAGGCCAACTCAGGAAATGAA
  AGGACGATTCTTATTTCCACTGCGGTTACTTTTGTGGATGTGTCTGCACCTGCAGAGGCAGGCTTCAGAG
  CTCCACCAGCCATCAATGCCAGGCTGCCCTTTAACTTCTTCTTCCCGTTTGTT
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC230238 representing NM_001173975
  Red=Cloning site Green=Tags(s)
  
  MCQLLESTVIQPQGDSPVAVLCVCDLSPAQCDINCCCDPDCSSVDFSVFSACSVPVVTGDSQFCSQKAVI
  YSLNFTANPPQRVFELVDQINPSIFCIHITNYKPALSFINPEVPDENNFDTLMKTSDGFTLNAESYVSFT
  TKLDIPTAAKYEYGVPLQTSDSFLRFPSSLTSSLCTDNNPAAFLVNQAVKCTRKINLEQCEEIEALSMAF
  YSSPEILRVPDSRKKVPITVQSIVIQSLNKTLTRREDTDVLQPTLVNAGHFSLCVNVVLEVKYSLTYTDA
  GEVTKADLSFVLGTVSSVVVPLQQKFEIHFLQENTQPVPLSGNPGYVVGLPLAAGFQPHKGSGIIQTTNR
  YGQLTILHSTTEQDCLALEGVRTPVLFGYTMQSGCKLRLTGALPCQLVAQKVKSLLWGQGFPDYVAPFGN
  SQAQDMLDWVPIHFITQSFNRKDSCQLPGALVIEVKWTKYGSLLNPQAKIVNVTANLISSSFPEANSGNE
  RTILISTAVTFVDVSAPAEAGFRAPPAINARLPFNFFFPFV
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001173975
• ORF Size: 1593 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001173975.1, NM_001173975.2, NP_001167446.1
• RefSeq ORF: 1596
• Locus ID: 79600
• Protein Families: Secreted Protein
• MW: 58.5 kDa
• Gene Summary: This gene encodes a member of a family of secreted and transmembrane proteins. The orthologous gene in mouse functions downstream of smoothened and rab23 to modulate hedgehog signal transduction. This protein is a component of the tectonic-like complex, which forms a barrier between the ciliary axoneme and the basal body. A mutation in this gene was found in a family with Joubert syndrome-13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]