TCTN1 (NM_001173975) Human Untagged Clone

CAT#: SC328876

TCTN1 (untagged)-Human tectonic family member 1 (TCTN1) transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TCTN1
• Synonyms: JBTS13; TECT1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001173975, the custom clone sequence may differ by one or more nucleotides
  ATGTGCCAGCTCCTGGAGTCCACAGTGATCCAACCTCAAGGGGACAGCCCCGTTGCTGTT
  CTCTGTGTCTGTGACTTATCCCCAGCACAGTGTGACATCAACTGCTGCTGTGATCCCGAC
  TGCAGCTCCGTGGATTTCAGTGTCTTTTCTGCCTGCTCAGTTCCAGTTGTCACGGGCGAC
  AGCCAGTTTTGTAGTCAAAAAGCAGTCATCTATTCATTGAATTTTACAGCAAACCCACCT
  CAAAGAGTATTTGAACTTGTTGACCAGATTAATCCATCTATTTTCTGCATTCATATTACA
  AACTATAAACCTGCATTATCCTTTATTAATCCAGAAGTACCTGATGAAAACAATTTTGAT
  ACATTGATGAAAACATCTGATGGTTTTACATTGAATGCTGAATCATATGTTTCCTTCACA
  ACCAAACTGGATATTCCTACTGCTGCTAAATATGAGTATGGGGTTCCTCTGCAGACTTCA
  GATTCGTTTCTGAGATTTCCTTCGTCCCTGACATCATCTCTGTGCACTGATAATAACCCT
  GCAGCGTTTCTGGTGAACCAGGCTGTTAAGTGCACCAGAAAAATAAATTTAGAACAGTGT
  GAAGAAATTGAAGCCCTCAGCATGGCTTTTTACAGCAGCCCGGAAATTCTGAGGGTACCT
  GATTCAAGAAAAAAGGTCCCTATCACTGTTCAGTCCATCGTCATTCAGTCTCTAAATAAA
  ACGCTCACCCGACGGGAGGACACTGATGTGCTGCAGCCGACTCTCGTCAACGCTGGACAC
  TTTAGCCTTTGCGTGAATGTTGTTCTTGAGGTAAAGTACAGCCTCACATACACAGATGCA
  GGTGAAGTCACCAAAGCTGATCTCTCATTCGTTCTGGGGACAGTTAGCAGCGTAGTGGTC
  CCACTGCAGCAAAAGTTTGAAATTCATTTTCTTCAGGAAAATACCCAGCCAGTCCCTCTC
  AGTGGAAACCCTGGTTATGTCGTGGGGCTCCCATTAGCTGCTGGATTCCAGCCTCATAAG
  GGGTCTGGGATTATTCAGACCACAAATAGATATGGACAGCTTACTATTCTTCATAGCACA
  ACTGAGCAAGACTGCTTAGCACTGGAGGGGGTCCGGACCCCAGTATTATTTGGTTACACT
  ATGCAATCTGGCTGTAAACTAAGACTGACTGGAGCTCTCCCGTGTCAGCTCGTAGCACAG
  AAGGTGAAGAGCCTGCTGTGGGGCCAGGGCTTCCCAGATTACGTGGCCCCTTTTGGAAAT
  TCCCAGGCCCAGGACATGCTGGACTGGGTGCCCATCCACTTCATCACCCAGTCATTCAAC
  AGGAAGGATTCCTGCCAGCTCCCAGGGGCTTTGGTTATAGAAGTGAAGTGGACTAAATAC
  GGATCCCTGCTGAATCCACAGGCCAAAATAGTCAATGTAACTGCAAATCTAATTTCATCC
  TCCTTTCCTGAGGCCAACTCAGGAAATGAAAGGACGATTCTTATTTCCACTGCGGTTACT
  TTTGTGGATGTGTCTGCACCTGCAGAGGCAGGCTTCAGAGCTCCACCAGCCATCAATGCC
  AGGCTGCCCTTTAACTTCTTCTTCCCGTTTGTTTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_001173975
• ORF Size: 1596 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001173975.1, NP_001167446.1
• RefSeq Size: 2006
• RefSeq ORF: 1596
• Locus ID: 79600
• Protein Families: Secreted Protein
• Gene Summary: This gene encodes a member of a family of secreted and transmembrane proteins. The orthologous gene in mouse functions downstream of smoothened and rab23 to modulate hedgehog signal transduction. This protein is a component of the tectonic-like complex, which forms a barrier between the ciliary axoneme and the basal body. A mutation in this gene was found in a family with Joubert syndrome-13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
  Transcript Variant: This variant (4) uses an alternate splice site in the 5' region, initiates translation at an alternate start codon, and uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The resulting isoform (4) has a distinct N-terminus and is shorter than isoform 1.