RIM1 (RIMS1) (NM_001168407) Human Tagged ORF Clone

CAT#: RC230619

RIMS1 (Myc-DDK-tagged)-Human regulating synaptic membrane exocytosis 1 (RIMS1), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: RIMS1
• Synonyms: CORD7; RAB3IP2; RIM; RIM1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC230619 representing NM_001168407
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTGTGCACCTGGGATTCATGTCTCTTCAGAAGGGTGGGAAGAAGTGAGGTCTGTTGATTCCGAAGAGG
  GAACAATTGAAGCTCGACGAGCAGTTGCTGGTGATTTGGATTATTACTGGTTGGATCCTGCCACGTGGCA
  CAGCCGGGAGACATCACCTATTAGTTCGCATCCTGTAACGTGGCAACCATCTAAAGAGGGGGACCGATTA
  ATTGGACGTGTTATTCTTAACAAGAGAACAACCATGCCCAAAGACTCAGGTGCATTGCTGGGTCTGAAAG
  TTGTTGGAGGAAAAATGACTGACTTAGGACGACTTGGTGCTTTCATCACCAAAGTAAAGAAGGGTAGCCT
  AGCAGATGTAGTTGGACACCTAAGAGCAGGGGATGAAGTTCTAGAATGGAATGGTAAACCCCTGCCGGGA
  GCTACAAATGAAGAAGTTTACAACATTATTTTAGAATCAAAATCAGAACCTCAAGTTGAAATTATTGTTT
  CAAGGCCTATTGGTGACATTCCCCGGATTCCTGAGAGCTCCCACCCTCCACTGGAGTCCAGTTCAAGTTC
  CTTTGAATCTCAGAAGATGGAAAGGCCTTCCATTTCTGTTATTTCTCCAACAAGTCCTGGAGCTCTAAAA
  GATGCCCCACAAGTCTTACCAGGGCAACTTTCTGTGAAGTTGTGGTATGATAAAGTGGGACACCAGCTGA
  TTGTAAATGTTCTGCAAGCAACAGATCTACCTGCTAGAGTAGATGGACGTCCTCGAAATCCCTATGTAAA
  AATGTATTTTCTTCCAGATAGAAGTGATAAAAGTAAAAGGAGGACCAAAACAGTAAAGAAAATACTAGAA
  CCAAAATGGAATCAAACTTTTGTCTATTCACATGTACATCGTAGAGATTTTAGAGAACGAATGTTAGAAA
  TAACTGTGTGGGACCAACCAAGAGTGCAAGAAGAAGAAAGTGAATTTCTTGGAGAGATCCTCATAGAATT
  GGAGACAGCGCTTTTAGATGATGAACCGCATTGGTATAAACTTCAGACACATGATGAGTCTTCACTACCT
  CTGCCTCAGCCATCACCTTTCATGCCAAGGCGACATATTCATGGAGAAAGCTCTAGCAAAAAGCTACAAA
  GATCTCAGCGAATCAGTGATAGTGACATCTCAGATTATGAGGTTGATGATGGTATTGGCGTAGTTCCTCC
  AGGCTATAGGTCTAGTGCTAGAGAAAGTAAATCTACAACATTAACTGTGCCAGAACAGCAAAGAACAACT
  CATCACCGCTCACGTTCAGTATCTCCTCATCGCGGCAATGATCAGGGAAAGCCGCGTTCACGTTTACCAA
  ATGTGCCATTACAGAGGAGTTTAGATGAAATTCATCCAACAAGAAGGTCACGTTCTCCAACCAGACACCA
  TGATGCCTCCCGAAGTCCAGTTGATCATAGAACCAGAGATGTGGATAGTCAGTATTTATCAGAACAAGAC
  AGTGAGCTTCTTATGCTGCCCAGAGCAAAACGAGGACGAAGTGCAGAATGCCTACATACTACCAGTGAAC
  TGCAGCCCTTTCTTGACAGGGCTAGGAGTGCTAGTACCAACTGCTTGAGACCAGATACTAGTTTGCATTC
  ACCAGAACGAGAAAGGCACTCCAGAAAGTCTGAAAGATCTAGCATCCAAAAACAGACTAGGAAAGGCACT
  GCCTCTGATGCAGAAAGAATGCACCGACAGAGAAGTCCAACACAATCTCCTCCAGCAGACACATCGTTCA
  GCAGTCGCAGGGGAAGACAGCTCCCACAAGTGCCAGTGAGAAGCGGCAGTATAGAACAAGCAAGCTTAGT
  AGTGGAGGAGCGAACAAGACAGATGAAAATGAAAGTGCATCGATTTAAGCAGACAACAGGGTCTGGTTCT
  AGTCAAGAACTTGATCGCGAGCAATATTCCAAGTATAACATACATAAAGATCAGTACAGAAGCTGTGATA
  ACGTCTCTGCCAAATCATCAGATAGTGATGTCAGTGATGTTTCCGCCATTTCCCGAACCAGCAGTGCCTC
  ACGCCTCAGCAGCACAAGCTTTATGTCAGAGCAATCTGAGCGCCCCAGGGGTAGAATCAGTTCATTTACC
  CCCAAAATGCAAGGCAGACGGATGGGGACTTCAGGAAGATCCATCATGAAGAGCACCAGTGTCAGTGGAG
  AGATGTACACACTGGAGCATAATGACGGCAGCCAGTCAGACACAGCTGTGGGTACAGTTGGAGCAGGTGG
  AAAGAAACGGAGATCCAGCCTTAGTGCCAAAGTGGTTGCCATAGTGTCTCGAAGGAGTAGAAGCACATCC
  CAGCTTAGTCAAACAGAGTCGGGCCACAAAAAGTTAAAAAGTACCATCCAGAGAAGCACAGAAACAGGCA
  TGGCAGCTGAAATGAGAAAGATGGTAAGGCAGCCGAGCCGAGAGTCTACTGATGGCAGCATCAACAGTTA
  CAGCTCTGAGGGCAATTTAATATTTCCTGGAGTGCGACTGGGAGCTGACAGTCAATTCAGTGATTTTCTT
  GATGGATTGGGACCAGCCCAGCTTGTTGGCCGCCAAACCCTTGCCACCCCTGCAATGGGTGATATACAAA
  TAGGAATGGAGGACAAAAAGGGCCAATTAGAAGTGGAAGTCATTAGAGCACGAAGCCTCACACAAAAGCC
  TGGTTCCAAATCTACACCTGCTCCATATGTCAAAGTATATCTTTTGGAAAATGGGGCCTGTATAGCCAAG
  AAGAAGACAAGAATTGCACGAAAAACCCTTGATCCTTTGTATCAGCAGTCTCTGGTTTTTGATGAAAGTC
  CACAGGGTAAAGTTCTTCAGGTGATTGTCTGGGGAGACTATGGCAGAATGGACCACAAATGCTTTATGGG
  TGTGGCTCAGATCTTGTTGGAAGAACTCGACCTGTCCAGCATGGTGATCGGATGGTACAAATTGTTCCCA
  CCGTCCTCACTGGTGGATCCCACACTCACTCCCCTCACCCGGCGGGCTTCCCAGTCATCTCTGGAAAGTT
  CAACTGGGCCTCCCTGTATTCGATCA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC230619 representing NM_001168407
  Red=Cloning site Green=Tags(s)
  
  MCAPGIHVSSEGWEEVRSVDSEEGTIEARRAVAGDLDYYWLDPATWHSRETSPISSHPVTWQPSKEGDRL
  IGRVILNKRTTMPKDSGALLGLKVVGGKMTDLGRLGAFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPG
  ATNEEVYNIILESKSEPQVEIIVSRPIGDIPRIPESSHPPLESSSSSFESQKMERPSISVISPTSPGALK
  DAPQVLPGQLSVKLWYDKVGHQLIVNVLQATDLPARVDGRPRNPYVKMYFLPDRSDKSKRRTKTVKKILE
  PKWNQTFVYSHVHRRDFRERMLEITVWDQPRVQEEESEFLGEILIELETALLDDEPHWYKLQTHDESSLP
  LPQPSPFMPRRHIHGESSSKKLQRSQRISDSDISDYEVDDGIGVVPPGYRSSARESKSTTLTVPEQQRTT
  HHRSRSVSPHRGNDQGKPRSRLPNVPLQRSLDEIHPTRRSRSPTRHHDASRSPVDHRTRDVDSQYLSEQD
  SELLMLPRAKRGRSAECLHTTSELQPFLDRARSASTNCLRPDTSLHSPERERHSRKSERSSIQKQTRKGT
  ASDAERMHRQRSPTQSPPADTSFSSRRGRQLPQVPVRSGSIEQASLVVEERTRQMKMKVHRFKQTTGSGS
  SQELDREQYSKYNIHKDQYRSCDNVSAKSSDSDVSDVSAISRTSSASRLSSTSFMSEQSERPRGRISSFT
  PKMQGRRMGTSGRSIMKSTSVSGEMYTLEHNDGSQSDTAVGTVGAGGKKRRSSLSAKVVAIVSRRSRSTS
  QLSQTESGHKKLKSTIQRSTETGMAAEMRKMVRQPSRESTDGSINSYSSEGNLIFPGVRLGADSQFSDFL
  DGLGPAQLVGRQTLATPAMGDIQIGMEDKKGQLEVEVIRARSLTQKPGSKSTPAPYVKVYLLENGACIAK
  KKTRIARKTLDPLYQQSLVFDESPQGKVLQVIVWGDYGRMDHKCFMGVAQILLEELDLSSMVIGWYKLFP
  PSSLVDPTLTPLTRRASQSSLESSTGPPCIRS
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001168407
• ORF Size: 3036 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001168407.1, NP_001161879.1
• RefSeq ORF: 3039
• Locus ID: 22999
• MW: 113.4 kDa
• Gene Summary: The protein encoded by this gene is a RAS gene superfamily member that regulates synaptic vesicle exocytosis. This gene also plays a role in the regulation of voltage-gated calcium channels during neurotransmitter and insulin release. Mutations have suggested a role cognition and have been identified as the cause of cone-rod dystrophy type 7. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012]