ADCY10 (NM_001167749) Human Tagged ORF Clone

CAT#: RC230718

ADCY10 (Myc-DDK-tagged)-Human adenylate cyclase 10 (soluble) (ADCY10), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: ADCY10
• Synonyms: HCA2; HEL-S-7a; hsAC; SAC; SACI; Sacy
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC230718 representing NM_001167749
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTTGGTCTTTGGAGATGAAACACACAGCCACTTTCTGGTGATTGGTCAGGCAGTGGACGATGTGCGCC
  TTGCCCAGAACATGGCTCAGATGAATGATGTTATTCTGTCACCAAACTGCTGGCAGCTCTGTGACCGGAG
  CATGATTGAAATTGAGAGTGTTCCAGATCAGAGAGCAGTTAAGGTTAACTTCTTAAAACCACCCCCCAAT
  TTTAATTTTGATGAATTTTTCACAAAGTGTACGACCTTCATGCATTATTATCCTTCTGGTGAGCACAAAA
  ACCTCCTGAGGCTTGCATGCACGCTGAAGCCTGATCCTGAACTGGAGATGTCCCTACAAAAGTATGTGAT
  GGAAAGCATTTTGAAGCAGATTGATAACAAACAGCTTCAGGGCTATTTATCTGAGCTTCGCCCAGTGACG
  ATTGTGTTTGTGAACCTGATGTTTGAAGACCAAGACAAAGCAGAAGAGATAGGCCCAGCCATCCAGGATG
  CCTATATGCACATCACTTCTGTCCTGAAGATCTTCCAAGGCCAAATCAATAAAGTCTTCATGTTTGACAA
  GGGCTGCTCTTTCCTCTGTGTCTTTGGCTTCCCTGGGGAAAAGGTACCTGACGAGCTCACTCATGCTCTG
  GAATGTGCTATGGATATATTTGACTTCTGCTCTCAAGTCCACAAAATCCAAACTGTATCCATCGGTGTTG
  CCAGTGGGATTGTCTTCTGTGGGATCGTTGGACACACTGTGAGACACGAGTACACAGTCATTGGTCAAAA
  AGTCAACTTAGCTGCCAGGATGATGATGTACTACCCAGGAATTGTGACCTGCGACTCTGTCACCTACAAT
  GGGAGCAACCTACCAGCGTACTTTTTTAAAGAGCTTCCAAAGAAAGTTATGAAAGGTGTTGCAGATTCTG
  GACCATTGTATCAGTATTGGGGCCGTACTGAGAAAGTCATGTTTGGTATGGCGTGCCTCATCTGCAACAG
  AAAGGAGGATTACCCTTTGCTGGGACGTAATAAAGAGATCAACTACTTCATGTATACTATGAAGAAATTT
  TTGATATCTAACAGCAGCCAAGTCTTAATGTATGAGGGATTACCAGGATATGGAAAAAGCCAGATACTTA
  TGAAAATTGAGTACCTGGCCCAAGGTAAGAATCACAGGATTATTGCCATTTCATTGAATAAGATCAGCTT
  CCATCAAACTTTCTATACCATCCAGATGTTCATGGCCAATGTCCTAGGCCTAGACACTTGTAAACATTAT
  AAAGAACGACAGACCAACCTTCGAAATAAAGTCATGACACTGTTGGATGAAAAGTTCTACTGTCTTCTTA
  ATGACATTTTCCATGTTCAGTTCCCTATTTCTCGGGAGATTTCCAGGATGAGCACCTTGAAAAAGCAAAA
  ACAATTGGAAATATTGTTTATGAAGATCTTGAAGCTGATAGTGAAAGAGGAAAGGATTATTTTTATCATT
  GATGAGGCCCAGTTTGTGGATTCGACCTCCTGGAGATTTATGGAGAAGCTTATCCGGACTCTTCCTATCT
  TCATCATTATGTCCCTGTGTCCCTTCGTTAACATTCCCTGTGCAGCTGCCAGGGCCGTAATAAAGAACAG
  GAACACCACCTACATTGTCATTGGTGCAGTACAGCCTAACGACATCTCCAACAAGATCTGTCTTGACCTC
  AATGTGAGCTGCATCTCCAAAGAACTGGACTCGTACCTGGGGGAGGGAAGCTGTGGGATTCCATTTTACT
  GTGAAGAATTGCTTAAAAACCTGGAACATCATGAGGTACTCGTTTTCCAACAAACGGAGTCTGAGGAAAA
  GACAAATAGGACCTGGAATAACCTGTTCAAGTATTCCATTAAGCTAACAGAGAAGTTAAACATGGTTACT
  CTCCATAGTGATAAGGAAAGTGAAGAAGTCTGTCACCTCACAAGTGGTGTCAGACTGAAAAACCTGTCAC
  CTCCAACGTCATTAAAAGAAATCTCTCTGATCCAGCTGGATAGCATGAGACTTTCCCACCAAATGCTGGT
  GAGATGTGCTGCCATCATTGGCCTGACCTTCACCACTGAGTTGTTGTTTGAGATTCTCCCCTGTTGGAAT
  ATGAAGATGATGATCAAGACCCTGGCAACCCTAGTGGAATCTAACATTTTTTATTGTTTCCGGAATGGCA
  AGGAGCTTCAAAAGGCCCTGAAACAGAATGATCCCTCATTTGAGGTGCACTATCGTTCCTTGTCTCTGAA
  GCCCAGTGAAGGGATGGATCACGGTGAAGAGGAACAGCTTCGTGAACTGGAGAATGAGGTGATCGAGTGC
  CACAGGATTCGATTCTGTAACCCTATGATGCAGAAAACAGCCTACGAGCTGTGGCTCAAGGACCAGAGAA
  AAGCCATGCACTTGAAATGTGCCCGCTTTTTAGAAGAAGATGCCCACAGATGTGACCACTGCCGAGGCAG
  GGACTTCATTCCCTATCATCACTTCACAGTGAATATTCGGCTCAACGCTTTAGACATGGATGCCATTAAA
  AAGATGGCTATGTCTCATGGATTTAAAACTGAAGAAAAGCTTATCTTGTCCAACTCAGAGATTCCTGAGA
  CATCTGCATTTTTTCCTGAAAATCGCAGTCCTGAAGAAATAAGAGAAAAGATCTTGAATTTCTTTGACCA
  CGTTTTAACAAAAATGAAGACATCTGACGAAGACATTATCCCTCTGGAATCTTGCCAGTGTGAAGAAATC
  CTAGAGATTGTCATCTTGCCTCTGGCCCACCATTTTCTGGCTTTGGGAGAAAATGACAAAGCCTTATATT
  ACTTCTTAGAAATTGCATCTGCTTATCTCATCTTTTGTGATAACTACATGGCATACATGTATTTGAATGA
  AGGACAGAAGTTGCTAAAAACTCTCAAGAAGGACAAATCTTGGAGCCAGACATTTGAGTCTGCCACCTTT
  TACAGCCTCAAAGGTGAGGTCTGTTTCAATATGGGCCAGATAGTGCTTGCCAAGAAAATGCTGAGGAAGG
  CACTGAAGCTCCTCAACCGAATCTTTCCTTACAACTTAATCTCCTTGTTTCTCCATATCCATGTCGAGAA
  AAACAGACACTTTCATTATGTGAATCGGCAGGCCCAAGAGAGCCCACCTCCAGGGAAGAAGAGGCTGGCA
  CAACTTTACCGGCAAACTGTCTGCCTTTCCTTGCTGTGGCGCATCTATAGCTACAGTTATCTTTTTCACT
  GCAAGTATTATGCCCACCTGGCAGTTATGATGCAAATGAATACTGCACTGGAAACTCAAAATTGTTTCCA
  GATCATTAAGGCTTACCTAGACTATTCGCTATACCACCACCTGGCTGGCTACAAAGGTGTGTGGTTCAAA
  TATGAAGTCATGGCCATGGAGCACATCTTCAACCTCCCCCTGAAAGGCGAGGGCATTGAAATCGTGGCAT
  ACGTGGCTGAGACACTGGTCTTCAACAAGCTCATAATGGGACACCTGGATTTGGCCATTGAGTTAGGCTC
  CCGAGCCCTTCAGATGTGGGCACTGCTCCAGAATCCCAACCGACATTATCAGTCCCTCTGCAGACTTAGC
  AGATGTCTCCTTCTGAACAGCAGATACCCGCAATTGATCCAGGTGCTGGGGCGGCTGTGGGAGCTTTCTG
  TAACACAGGAACACATCTTCAGCAAGGCATTTTTCTATTTTGTCTGCTTGGACATCCTGCTTTATTCTGG
  TTTTGTTTATAGAACATTTGAAGAATGTTTGGAATTCATACACCAATACGAAAACAACAGAATCCTCAAG
  TTCCACAGTGGACTCCTCCTGGGACTTTATTCCTCTGTAGCTATCTGGTATGCCAGACTTCAGGAATGGG
  ACAACTTTTACAAATTTTCCAATAGAGCTAAAAATCTTTTGCCAAGAAGAACCATGACACTTACTTACTA
  TGACGGAATATCTAGGTACATGGAGGGGCAAGTTCTTCACCTTCAAAAACAAATCAAAGAACAGTCAGAG
  AATGCCCAAGCCAGTGGGGAGGAGCTACTCAAGAACTTGGAGAATCTGGTGGCTCAAAATACCACTGGCC
  CTGTCTTTTGCCCAAGGCTCTACCACCTGATGGCTTACGTCTGTATATTAATGGGAGATGGGCAGAAATG
  TGGCCTCTTCCTGAACACAGCCTTGCGGCTCTCTGAAACACAGGGGAATATACTGGAGAAATGCTGGCTG
  AACATGAACAAAGAATCATGGTACTCAACCTCTGAGTTAAAAGAAGACCAATGGCTTCAGACGATCTTGA
  GTCTCCCATCATGGGAAAAAATTGTAGCAGGCAGGGTAAACATTCAGGATCTTCAAAAAAACAAATTCCT
  GATGAGAGCTAATACCGTGGACAATCATTTC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC230718 representing NM_001167749
  Red=Cloning site Green=Tags(s)
  
  MLVFGDETHSHFLVIGQAVDDVRLAQNMAQMNDVILSPNCWQLCDRSMIEIESVPDQRAVKVNFLKPPPN
  FNFDEFFTKCTTFMHYYPSGEHKNLLRLACTLKPDPELEMSLQKYVMESILKQIDNKQLQGYLSELRPVT
  IVFVNLMFEDQDKAEEIGPAIQDAYMHITSVLKIFQGQINKVFMFDKGCSFLCVFGFPGEKVPDELTHAL
  ECAMDIFDFCSQVHKIQTVSIGVASGIVFCGIVGHTVRHEYTVIGQKVNLAARMMMYYPGIVTCDSVTYN
  GSNLPAYFFKELPKKVMKGVADSGPLYQYWGRTEKVMFGMACLICNRKEDYPLLGRNKEINYFMYTMKKF
  LISNSSQVLMYEGLPGYGKSQILMKIEYLAQGKNHRIIAISLNKISFHQTFYTIQMFMANVLGLDTCKHY
  KERQTNLRNKVMTLLDEKFYCLLNDIFHVQFPISREISRMSTLKKQKQLEILFMKILKLIVKEERIIFII
  DEAQFVDSTSWRFMEKLIRTLPIFIIMSLCPFVNIPCAAARAVIKNRNTTYIVIGAVQPNDISNKICLDL
  NVSCISKELDSYLGEGSCGIPFYCEELLKNLEHHEVLVFQQTESEEKTNRTWNNLFKYSIKLTEKLNMVT
  LHSDKESEEVCHLTSGVRLKNLSPPTSLKEISLIQLDSMRLSHQMLVRCAAIIGLTFTTELLFEILPCWN
  MKMMIKTLATLVESNIFYCFRNGKELQKALKQNDPSFEVHYRSLSLKPSEGMDHGEEEQLRELENEVIEC
  HRIRFCNPMMQKTAYELWLKDQRKAMHLKCARFLEEDAHRCDHCRGRDFIPYHHFTVNIRLNALDMDAIK
  KMAMSHGFKTEEKLILSNSEIPETSAFFPENRSPEEIREKILNFFDHVLTKMKTSDEDIIPLESCQCEEI
  LEIVILPLAHHFLALGENDKALYYFLEIASAYLIFCDNYMAYMYLNEGQKLLKTLKKDKSWSQTFESATF
  YSLKGEVCFNMGQIVLAKKMLRKALKLLNRIFPYNLISLFLHIHVEKNRHFHYVNRQAQESPPPGKKRLA
  QLYRQTVCLSLLWRIYSYSYLFHCKYYAHLAVMMQMNTALETQNCFQIIKAYLDYSLYHHLAGYKGVWFK
  YEVMAMEHIFNLPLKGEGIEIVAYVAETLVFNKLIMGHLDLAIELGSRALQMWALLQNPNRHYQSLCRLS
  RCLLLNSRYPQLIQVLGRLWELSVTQEHIFSKAFFYFVCLDILLYSGFVYRTFEECLEFIHQYENNRILK
  FHSGLLLGLYSSVAIWYARLQEWDNFYKFSNRAKNLLPRRTMTLTYYDGISRYMEGQVLHLQKQIKEQSE
  NAQASGEELLKNLENLVAQNTTGPVFCPRLYHLMAYVCILMGDGQKCGLFLNTALRLSETQGNILEKCWL
  NMNKESWYSTSELKEDQWLQTILSLPSWEKIVAGRVNIQDLQKNKFLMRANTVDNHF
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001167749
• ORF Size: 4371 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001167749.1, NM_001167749.2, NP_001161221.1
• RefSeq Size: 4977
• RefSeq ORF: 4374
• Locus ID: 55811
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Purine metabolism
• MW: 169.7 kDa
• Gene Summary: The protein encoded by this gene belongs to a distinct class of adenylyl cyclases that is soluble and insensitive to G protein or forskolin regulation. Activity of this protein is regulated by bicarbonate. Variation at this gene has been observed in patients with absorptive hypercalciuria. Alternatively spliced transcript variants encoding different isoforms have been observed. There is a pseudogene of this gene on chromosome 6. [provided by RefSeq, Jul 2014]