ADCY10 (NM_001167749) Human Tagged ORF Clone

CAT#: RC230718L4

Lenti-ORF clone of ADCY10 (mGFP-tagged)-Human adenylate cyclase 10 (soluble) (ADCY10), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: ADCY10
• Synonyms: HCA2; HEL-S-7a; hsAC; SAC; SACI; Sacy
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC230718).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_001167749
• ORF Size: 4371 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001167749.2, NP_001161221.1
• RefSeq Size: 4977
• RefSeq ORF: 4374
• Locus ID: 55811
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Purine metabolism
• MW: 169.7 kDa
• Gene Summary: The protein encoded by this gene belongs to a distinct class of adenylyl cyclases that is soluble and insensitive to G protein or forskolin regulation. Activity of this protein is regulated by bicarbonate. Variation at this gene has been observed in patients with absorptive hypercalciuria. Alternatively spliced transcript variants encoding different isoforms have been observed. There is a pseudogene of this gene on chromosome 6. [provided by RefSeq, Jul 2014]