GPR161 (NM_001267612) Human Tagged ORF Clone

CAT#: RC232654

GPR161 (Myc-DDK tagged) - Homo sapiens G protein-coupled receptor 161 (GPR161), transcript variant 5

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: GPR161
• Synonyms: RE2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC232654 representing NM_001267612
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGTGTACCCCATGAAGATCACAGGGAACCGGGCTGTGATGGCACTTGTCTACATCTGGCTTCACTCGC
  TCATCGGCTGCCTGCCACCCCTGTTTGGTTGGTCATCCGTGGAGTTTGACGAGTTCAAATGGATGTGTGT
  GGCTGCTTGGCACCGGGAGCCTGGCTACACGGCCTTCTGGCAGATCTGGTGTGCCCTCTTCCCCTTTCTG
  GTCATGCTGGTGTGCTATGGCTTCATCTTCCGCGTGGCCAGGGTCAAGGCACGCAAGGTGCACTGTGGCA
  CAGTCGTCATCGTGGAGGAGGATGCTCAGAGGACCGGGAGGAAGAACTCCAGCACCTCCACCTCCTCTTC
  AGGCAGCAGGAGGAATGCCTTTCAGGGTGTGGTCTACTCGGCCAACCAGTGCAAAGCCCTCATCACCATC
  CTGGTGGTCCTCGGTGCCTTCATGGTCACCTGGGGCCCCTACATGGTTGTCATCGCCTCTGAGGCCCTCT
  GGGGGAAAAGCTCCGTCTCCCCGAGCCTGGAGACTTGGGCCACATGGCTGTCCTTTGCCAGCGCTGTCTG
  CCACCCCCTGATCTATGGACTCTGGAACAAGACAGTTCGCAAAGAACTACTGGGCATGTGCTTTGGGGAC
  CGGTATTATCGGGAACCATTTGTGCAACGACAGAGGACTTCCAGGCTCTTCAGCATTTCCAACAGGATCA
  CAGACCTGGGCCTGTCCCCACACCTCACTGCGCTCATGGCAGGTGGACAGCCCCTGGGGCACAGCAGCAG
  CACGGGGGACACTGGCTTCAGCTGCTCCCAGGACTCAGGGACAGATATGATGCTGCTTGAGGACTACACG
  TCTGATGACAACCCTCCCTCTCACTGCACTTGCCCACCCAAGAGAAGGAGCTCGGTGACATTTGAGGATG
  AAGTGGAACAAATCAAAGAAGCTGCCAAGAACTCGATTCTTCATGTGAAAGCTGAAGTACACAAGTCCTT
  GGACAGTTACGCAGCAAGCTTGGCCAAAGCCATTGAGGCCGAAGCCAAAATCAACTTATTTGGGGAGGAG
  GCTTTGCCAGGGGTCTTGGTTACAGCACGGACTGTCCCGGGGGGCGGCTTCGGGGGCCGCCGAGGCAGCA
  GAACTCTTGTGAGCCAGAGGCTGCAGTTGCAGAGCATCGAAGAAGGAGATGTTTTAGCTGCCGAGCAGAG
  A
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC232654 representing NM_001267612
  Red=Cloning site Green=Tags(s)
  
  MVYPMKITGNRAVMALVYIWLHSLIGCLPPLFGWSSVEFDEFKWMCVAAWHREPGYTAFWQIWCALFPFL
  VMLVCYGFIFRVARVKARKVHCGTVVIVEEDAQRTGRKNSSTSTSSSGSRRNAFQGVVYSANQCKALITI
  LVVLGAFMVTWGPYMVVIASEALWGKSSVSPSLETWATWLSFASAVCHPLIYGLWNKTVRKELLGMCFGD
  RYYREPFVQRQRTSRLFSISNRITDLGLSPHLTALMAGGQPLGHSSSTGDTGFSCSQDSGTDMMLLEDYT
  SDDNPPSHCTCPPKRRSSVTFEDEVEQIKEAAKNSILHVKAEVHKSLDSYAASLAKAIEAEAKINLFGEE
  ALPGVLVTARTVPGGGFGGRRGSRTLVSQRLQLQSIEEGDVLAAEQR
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001267612
• ORF Size: 1191 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001267612.1, NP_001254541.1
• RefSeq Size: 7771
• RefSeq ORF: 1194
• Locus ID: 23432
• Protein Families: Druggable Genome, GPCR, Transmembrane
• MW: 44.4 kDa
• Gene Summary: The protein encoded by this gene is an orphan G protein-coupled receptor whose ligand is unknown. This gene is overexpressed in triple-negative breast cancer, and disruption of this gene slows the proliferation of basal breast cancer cells. Therefore, this gene is a potential drug target for triple-negative breast cancer. [provided by RefSeq, Mar 2017]