IRG1 (ACOD1) (NM_001258406) Human Tagged ORF Clone
CAT#: RC232825L3
- LentiORF®
Lenti ORF clone of Human aconitate decarboxylase 1 (ACOD1), Myc-DDK-tagged
"NM_001258406" in other vectors (6)
Specifications
Product Data | |
Tag | Myc-DDK |
Symbol | IRG1 |
Synonyms | CAD; IRG1 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC232825).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_001258406 |
ORF Size | 1443 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001258406.1, NP_001245335.1 |
RefSeq Size | 2111 bp |
RefSeq ORF | 1446 bp |
Locus ID | 730249 |
UniProt ID | A6NK06 |
Cytogenetics | 13q22.3 |
MW | 53.1 kDa |
Gene Summary | Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC330681 | IRG1 (untagged) - Homo sapiens immunoresponsive 1 homolog (mouse) (IRG1) |
USD 480.00 |
|
RC232825 | IRG1 (Myc-DDK tagged) - Homo sapiens immunoresponsive 1 homolog (mouse) (IRG1) |
USD 420.00 |
|
RG232825 | IRG1 (GFP-tagged) - Homo sapiens immunoresponsive 1 homolog (mouse) (IRG1) |
USD 460.00 |
|
RC232825L1 | Lenti ORF clone of Human aconitate decarboxylase 1 (ACOD1), Myc-DDK-tagged |
USD 620.00 |
|
RC232825L2 | Lenti ORF clone of Human aconitate decarboxylase 1 (ACOD1), mGFP tagged |
USD 620.00 |
|
RC232825L4 | Lenti ORF clone of Human aconitate decarboxylase 1 (ACOD1), mGFP tagged |
USD 620.00 |
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