C1orf2 (FAM189B) (NM_001267608) Human Tagged ORF Clone

CAT#: RC234654

FAM189B (Myc-DDK tagged) - Homo sapiens family with sequence similarity 189, member B (FAM189B), transcript variant 3

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: FAM189B
• Synonyms: C1orf2; COTE1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC234654 representing NM_001267608
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGATGCCCTCGCCTAGTGACTCCAGCCGCTCGCTGACCAGCCGGCCCAGCACCAGGGGCCTTACCCACC
  TCCGCCTCCACCGACCCTGGCTGCAGGCCCTGCTTACGCTGGGGCTGGTCCAAGTGCTCCTGGGCATCCT
  GGTGGTCACCTTCAGCATGGTGGCCTCTTCCGTCACCACCACCGAGAGCATCAAGAGGTCCTGCCCGTCT
  TGGGCTGGGTTCTCGATCTCCTTCTTCTCCTTGCTTTCGGTGCTCTGTGTCATGCTTAGCATGGCTGGCT
  CTGTTCTCTCCTGTAAGAATGCTCAACTGGCCCGAGACTTCCAACAGTGCTCTCTGGAAGGAAAGGTCTG
  TGTGTGCTGTCCCTCTGTTCCCCTCCTCCGGCCCTGTCCAGAGTCGGGGCAGGAACTGAAAGTTGCCCCT
  AACTCCACCTGTGATGAAGCCCGAGGGGCCCTCAAGAACCTGCTCTTCAGCGTCTGTGGGCTCACCATTT
  GTGCCGCTATAATCTGTACACTCTCTGCTATTGTCTGCTGCATCCAAATCTTCTCCCTGGACCTCGTGCA
  TACGCAGCTGGCCCCTGAGCGGTCAGTCTCAGGCCCACTGGGACCTCTGGGCTGCACGTCCCCGCCCCCA
  GCCCCTCTCCTACACACCATGCTGGACCTGGAGGAATTTGTCCCGCCTGTGCCCCCACCGCCCTACTATC
  CCCCAGAGTATACCTGCAGCTCAGAAACAGATGCACAGAGCATCACGTACAATGGCTCCATGGACAGCCC
  AGTGCCCTTGTACCCTACCGATTGCCCCCCTTCTTATGAGGCAGTCATGGGACTACGAGGAGACAGCCAG
  GCCACTCTCTTTGACCCTCAGCTTCACGATGGCTCGTGCATCTGTGAACGAGTGGCCTCCATTGTAGACG
  TGTCCATGGACAGCGGGTCTCTGGTGCTGTCAGCCATTGGTGACCTCCCTGGGGGCTCTAGCCCGTCGGA
  GGACTCGTGCCTGCTGGAGCTGCAGGGCTCCGTGCGCTCCGTGGACTACGTTCTCTTTCGCTCCATCCAG
  CGCAGCCGTGCCGGCTACTGCCTCAGCCTGGACTGTGGCCTGCGGGGCCCCTTCGAGGAAAGCCCCCTGC
  CACGGCGCCCCCCACGGGCTGCCCGCTCCTATTCCTGCTCTGCCCCTGAAGCTCCACCCCCACTGGGTGC
  CCCCACAGCTGCCCGCAGCTGCCACCGGTTGGAGGGCTGGCCGCCCTGGGTGGGACCCTGCTTCCCCGAG
  CTGAGGCGGCGGGTCCCCCGGGGAGGGGGCCGCCCAGCCGCAGCCCCGCCCACCCGAGCCCCGACTCGTC
  GCTTCAGCGATAGCTCAGGTTCCCTCACCCCACCGGGGCACCGGCCTCCTCATCCGGCATCCCCACCACC
  GCTGCTGCTGCCACGGTCCCACAGCGACCCAGGCATCACGACCTCCAGTGACACTGCTGACTTCAGGGAC
  CTTTATACCAAAGTGCTTGAGGAAGAAGCTGCTTCTGTTTCCTCTGCAGATACAGGGCTCTGCTCTGAAG
  CCTGCCTCTTCCGCCTAGCCCGCTGCCCTTCCCCCAAGTTGCTACGTGCCCGGTCAGCCGAGAAACGGCG
  CCCTGTGCCCACCTTCCAAAAAGTTCCCCTGCCCTCGGGCCCTGCACCTGCCCACTCCCTGGGGGACCTA
  AAGGGCAGCTGGCCAGGTCGGGGCCTGGTCACTCGTTTCCTCCAGATATCCAGGAAAGCCCCAGACCCCA
  GTGGGACTGGAGCTCATGGACATAAGCAGGTGCCCCGGAGCCTGTGGGGCCGGCCTGGCCGAGAGAGCCT
  CCACCTTCGCAGCTGCGGAGATCTGAGCTCTAGCTCTTCCCTGCGGCGTCTCCTGTCTGGCCGCAGGCTG
  GAGCGTGGTACCCGCCCCCACAGCCTCAGCCTCAACGGGGGCAGCCGGGAGACTGGGCTC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC234654 representing NM_001267608
  Red=Cloning site Green=Tags(s)
  
  MMPSPSDSSRSLTSRPSTRGLTHLRLHRPWLQALLTLGLVQVLLGILVVTFSMVASSVTTTESIKRSCPS
  WAGFSISFFSLLSVLCVMLSMAGSVLSCKNAQLARDFQQCSLEGKVCVCCPSVPLLRPCPESGQELKVAP
  NSTCDEARGALKNLLFSVCGLTICAAIICTLSAIVCCIQIFSLDLVHTQLAPERSVSGPLGPLGCTSPPP
  APLLHTMLDLEEFVPPVPPPPYYPPEYTCSSETDAQSITYNGSMDSPVPLYPTDCPPSYEAVMGLRGDSQ
  ATLFDPQLHDGSCICERVASIVDVSMDSGSLVLSAIGDLPGGSSPSEDSCLLELQGSVRSVDYVLFRSIQ
  RSRAGYCLSLDCGLRGPFEESPLPRRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPE
  LRRRVPRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASPPPLLLPRSHSDPGITTSSDTADFRD
  LYTKVLEEEAASVSSADTGLCSEACLFRLARCPSPKLLRARSAEKRRPVPTFQKVPLPSGPAPAHSLGDL
  KGSWPGRGLVTRFLQISRKAPDPSGTGAHGHKQVPRSLWGRPGRESLHLRSCGDLSSSSSLRRLLSGRRL
  ERGTRPHSLSLNGGSRETGL
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001267608
• ORF Size: 1950 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001267608.1, NP_001254537.1
• RefSeq Size: 3154
• RefSeq ORF: 1953
• Locus ID: 10712
• Protein Families: Transmembrane
• MW: 69.9 kDa
• Gene Summary: This gene is located near the gene for the lysosomal enzyme glucosylceramidase; a deficiency in this enzyme is associated with Gaucher disease. The encoded protein has been identified as a potential binding partner of a WW domain-containing protein which is involved in apoptosis and tumor suppression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]